Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Sharon L Reed"'
Autor:
Jair L Siqueira-Neto, Anjan Debnath, Laura-Isobel McCall, Jean A Bernatchez, Momar Ndao, Sharon L Reed, Philip J Rosenthal
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 8, p e0006512 (2018)
Cysteine proteases (CPs) play key roles in the pathogenesis of protozoan parasites, including cell/tissue penetration, hydrolysis of host or parasite proteins, autophagy, and evasion or modulation of the host immune response, making them attractive c
Externí odkaz:
https://doaj.org/article/6e7dfcafb6c748d985da28a4ff16d972
Autor:
Juan D Chaparro, Timmy Cheng, Uyen Phuong Tran, Rosa M Andrade, Sara B T Brenner, Grace Hwang, Shara Cohn, Ken Hirata, James H McKerrow, Sharon L Reed
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193982 (2018)
Although toxoplasmosis is one of the most common parasitic infections worldwide, therapeutic options remain limited. Cathepsins, proteases that play key roles in the pathogenesis of toxoplasmosis and many other protozoan infections, are important pot
Externí odkaz:
https://doaj.org/article/8010fa95326a4d13bbb16cb478193158
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e2973 (2014)
The mainstay of toxoplasmosis treatment targets the folate biosynthetic pathways and has not changed for the last 50 years. The activity of these chemotherapeutic agents is restricted to one lifecycle stage of Toxoplasma gondii, they have significant
Externí odkaz:
https://doaj.org/article/f888d5a5dbb642839ed61b21f53c138f
Autor:
Nathaniel L. Matteson, Gabriel W. Hassler, Ezra Kurzban, Madison A. Schwab, Sarah A. Perkins, Karthik Gangavarapu, Joshua I. Levy, Edyth Parker, David Pride, Abbas Hakim, Peter De Hoff, Willi Cheung, Anelizze Castro-Martinez, Andrea Rivera, Anthony Veder, Ariana Rivera, Cassandra Wauer, Jacqueline Holmes, Jedediah Wilson, Shayla N. Ngo, Ashley Plascencia, Elijah S. Lawrence, Elizabeth W. Smoot, Emily R. Eisner, Rebecca Tsai, Marisol Chacón, Nathan A. Baer, Phoebe Seaver, Rodolfo A. Salido, Stefan Aigner, Toan T. Ngo, Tom Barber, Tyler Ostrander, Rebecca Fielding-Miller, Elizabeth H. Simmons, Oscar E. Zazueta, Idanya Serafin-Higuera, Manuel Sanchez-Alavez, Jose L. Moreno-Camacho, Abraham García-Gil, Ashleigh R. Murphy Schafer, Eric McDonald, Jeremy Corrigan, John D. Malone, Sarah Stous, Seema Shah, Niema Moshiri, Alana Weiss, Catelyn Anderson, Christine M. Aceves, Emily G. Spencer, Emory C. Hufbauer, Justin J. Lee, Karthik S. Ramesh, Kelly N. Nguyen, Kieran Saucedo, Refugio Robles-Sikisaka, Kathleen M. Fisch, Steven L. Gonias, Amanda Birmingham, Daniel McDonald, Smruthi Karthikeyan, Natasha K. Martin, Robert T. Schooley, Agustin J. Negrete, Horacio J. Reyna, Jose R. Chavez, Maria L. Garcia, Jose M. Cornejo-Bravo, David Becker, Magnus Isaksson, Nicole L. Washington, William Lee, Richard S. Garfein, Marco A. Luna-Ruiz Esparza, Jonathan Alcántar-Fernández, Benjamin Henson, Kristen Jepsen, Beatriz Olivares-Flores, Gisela Barrera-Badillo, Irma Lopez-Martínez, José E. Ramírez-González, Rita Flores-León, Stephen F. Kingsmore, Alison Sanders, Allorah Pradenas, Benjamin White, Gary Matthews, Matt Hale, Ronald W. McLawhon, Sharon L. Reed, Terri Winbush, Ian H. McHardy, Russel A. Fielding, Laura Nicholson, Michael M. Quigley, Aaron Harding, Art Mendoza, Omid Bakhtar, Sara H. Browne, Jocelyn Olivas Flores, Diana G. Rincon Rodríguez, Martin Gonzalez Ibarra, Luis C. Robles Ibarra, Betsy J. Arellano Vera, Jonathan Gonzalez Garcia, Alicia Harvey-Vera, Rob Knight, Louise C. Laurent, Gene W. Yeo, Joel O. Wertheim, Xiang Ji, Michael Worobey, Marc A. Suchard, Kristian G. Andersen, Abraham Campos-Romero, Shirlee Wohl, Mark Zeller
SummaryThe maturation of genomic surveillance in the past decade has enabled tracking of the emergence and spread of epidemics at an unprecedented level. During the COVID-19 pandemic, for example, genomic data revealed that local epidemics varied con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56eb36f6e3f6f8a66062020bd8edb574
https://doi.org/10.1101/2023.03.14.23287217
https://doi.org/10.1101/2023.03.14.23287217
Autor:
Raymond T. Suhandynata, Kyle Lund, Nicholas J Bevins, Andrés Mauricio Caraballo-Rodríguez, Sharon L. Reed, Robert L. Fitzgerald, Pieter C. Dorrestein
Publikováno v:
Lab Med
Objective Antibiotic resistance by beta lactamase expression is a serious and growing threat. We aimed to determine whether beta-lactamase activity is detectable in urine specimens to enable faster identification of resistance. Methods Urine specimen
Publikováno v:
Pathogens, Vol 8, Iss 4, p 165 (2019)
This study aimed to determine the presence of giardiasis among HIV patients in San Diego, the rate of failure of metronidazole treatment, and factors associated with treatment failure. We used a 7 year retrospective single-center case series of HIV-i
Externí odkaz:
https://doaj.org/article/39cc40fd9f1047c0af3bef6dd4da2d6a
Publikováno v:
Mycoses. 63:553-557
Background Coccidioides spp. are dimorphic fungi endemic to parts of the United States, Mexico, Central and South America. Infection can cause a range of disease from self-limited acute pneumonia to severe disseminated disease. Methods We performed a
Publikováno v:
Journal of Infection. 78:249-259
Publikováno v:
Mycoses. 62:230-236
Background We compared new Aspergillus Galactomannan Lateral Flow Assay with the newly formatted Aspergillus-specific Lateral Flow device tests for the diagnosis of invasive pulmonary aspergillosis (IPA) in non-neutropenic patients. Methods We perfor
Autor:
Michael J. Kelner, Jenny Tuyet Tran, David Nemazee, James E. Voss, Deli Huang, Melissa A Hoffman, Raymond T. Suhandynata, Robert L. Fitzgerald, Ronald W. McLawhon, Sharon L. Reed
Publikováno v:
Clinical chemistry, vol 67, iss 2
Clinical Chemistry
Clinical Chemistry
BackgroundCurrently it is unknown whether a positive serology results correlates with protective immunity against SARS-CoV-2. There are also concerns regarding the low positive predictive value of SARS-CoV-2 serology tests, especially when testing po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bf61e9484594832362e1aef782584c
https://escholarship.org/uc/item/7m37937r
https://escholarship.org/uc/item/7m37937r