Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sharon L Gardner"'
Autor:
Nishanth S. Iyengar, Danielle Golub, Michelle W. McQuinn, Travis Hill, Karen Tang, Sharon L. Gardner, David H. Harter, Chandranath Sen, David A. Staffenberg, Kristen Thomas, Zachary Elkin, Irina Belinsky, Christopher William
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-8 (2020)
Abstract Inflammatory orbital lesions include a broad list of diagnoses, many of them with overlapping clinical and radiographic features. They often present a diagnostic conundrum, even to the most experienced orbital specialist, thus placing consid
Externí odkaz:
https://doaj.org/article/c615e156ebb04ca0afb3ed45e0aefa96
Autor:
Matija Snuderl, Kasthuri Kannan, Elke Pfaff, Shiyang Wang, James M. Stafford, Jonathan Serrano, Adriana Heguy, Karina Ray, Arline Faustin, Olga Aminova, Igor Dolgalev, Stacie L. Stapleton, David Zagzag, Luis Chiriboga, Sharon L. Gardner, Jeffrey H. Wisoff, John G. Golfinos, David Capper, Volker Hovestadt, Marc K. Rosenblum, Dimitris G. Placantonakis, Sarah E. LeBoeuf, Thales Y. Papagiannakopoulos, Lukas Chavez, Sama Ahsan, Charles G. Eberhart, Stefan M. Pfister, David T. W. Jones, Matthias A. Karajannis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pineoblastoma is a highly aggressive and rare childhood brain cancer, and the genetic drivers of sporadic pineoblastoma are unknown. Here, the authors genomically interrogated pediatric and adult pineoblastomas and found novel variants including recu
Externí odkaz:
https://doaj.org/article/ead93584496f48eaacd71d7cac4d1501
Autor:
A Samer Al-Homsi, Frank Cirrone, Stephanie Wo, Kelli Cole, J Andres Suarez-Londono, Sharon L Gardner, Jingmei Hsu, Kelsey Stocker, Benedetto Bruno, Judith D. Goldberg, Benjamin A Levinson, Maher Abdul-Hay
Publikováno v:
Blood Advances.
Reducing the incidence of graft-versus host disease (GvHD) following haploidentical hematopoietic stem cell transplantation (HSCT) is warranted. Post-transplant cyclophosphamide (PTCy) is the main agent used for GvHD prevention in this setting. It re
Autor:
A Samer Al-Homsi, Frank Cirrone, Kelli Cole, Jaime Andres Suarez-Londono, Sharon L. Gardner, Jingmei Hsu, Stephanie Wo, Kelsey Stocker, Benedetto Bruno, Judith Goldberg, Benjamin Levinson, Maher Abdul-Hay
Publikováno v:
Blood. 140:7628-7630
Autor:
Jessica Stiefel, Allyson M. Flower, Marissa Botwinick, Maegan Ford, Alycia Foti, Mital Gandhi, Justin Slovin, Elana Smilow, Ashley Bowers, Hannah Karpel, Leya Y Schwartz, Ellen Fraint, Lisa M. Gennarini, Sharon L. Gardner, Elizabeth A. Raetz, Niketa C. Shah, Jing Chen, Jennifer Krajewski, Nobuko Hijiya, Prakash Satwani, Jessica C Hochberg, Audrey Mauguen, Kevin J. Curran, Maria Luisa Sulis
Publikováno v:
Blood. 140:7763-7765
Autor:
Daniel C Bowers, Veena Rajaram, Matthias A Karajannis, Sharon L Gardner, Jack Meng-Fen Su, Patricia Baxter, Sonia Partap, Laura J Klesse
Publikováno v:
Neuro-Oncology Advances. 5
BackgroundPreclinical studies have suggested that mTOR pathway signaling may be a potential therapeutic target for childhood ependymoma.MethodsA phase II clinical trial (ClinicalTrials.gov identifier: NCT02155920) of single-agent everolimus was perfo
Autor:
Mekka R Garcia, Yang Feng, Varshini Vasudevaraja, Kristyn Galbraith, Jonathan Serrano, Cheddhi Thomas, Alireza Radmanesh, Eveline T Hidalgo, David H Harter, Jeffrey C Allen, Sharon L Gardner, Diana S Osorio, Christopher M William, David Zagzag, Daniel R Boué, Matija Snuderl
Publikováno v:
Journal of neuropathology and experimental neurology. 81(11)
Diffuse spinal cord gliomas (SCGs) are rare tumors associated with a high morbidity and mortality that affect both pediatric and adult populations. In this retrospective study, we sought to characterize the clinical, pathological, and molecular featu
Autor:
Evan Cantor, Kyle Wierzbicki, Rohinton S Tarapore, Karthik Ravi, Chase Thomas, Rodrigo Cartaxo, Viveka Nand Yadav, Ramya Ravindran, Amy K Bruzek, Jack Wadden, Vishal John, Clarissa May Babila, Jessica R Cummings, Abed Rahman Kawakibi, Sunjong Ji, Johanna Ramos, Alyssa Paul, Dustin Walling, Marcia Leonard, Patricia Robertson, Andrea Franson, Rajen Mody, Hugh J L Garton, Sriram Venneti, Yazmin Odia, Cassie Kline, Nicholas A Vitanza, Soumen Khatua, Sabine Mueller, Joshua E Allen, Sharon L Gardner, Carl Koschmann
Publikováno v:
Neuro Oncol
Background Diffuse Midline Glioma (DMG) with the H3K27M mutation is a lethal childhood brain cancer, with patients rarely surviving 2 years from diagnosis. Methods We conducted a multi-site Phase 1 trial of the imipridone ONC201 for children with H3K
Autor:
Sharon L Gardner, Rohinton S Tarapore, Jeffrey Allen, Susan L McGovern, Wafik Zaky, Yazmin Odia, Doured Daghistani, Zuanel Diaz, Matthew D Hall, Ziad Khatib, Carl Koschmann, Evan Cantor, Ryo Kurokawa, Tobey J MacDonald, Dolly Aguilera, Nicholas A Vitanza, Sabine Mueller, Cassie Kline, Guangrong Lu, Joshua E Allen, Soumen Khatua
Publikováno v:
Neuro-Oncology Advances. 4
Background ONC201, a dopamine receptor D2 (DRD2) antagonist and caseinolytic protease P (ClpP) agonist, has induced durable tumor regressions in adults with recurrent H3 K27M-mutant glioma. We report results from the first phase I pediatric clinical
Autor:
Yazmin Odia, Carl Johannes Koschmann, Rohinton Tarapore, Jeffrey Allen, Wafik Tharwat Zaky, Matthew David Hall, Doured Daghistani, Ziad Khatib, Dolly Aguilera, Tobey J. MacDonald, Peter de Blank, Susan L. McGovern, Sabine Mueller, Cassie Kline, Nicholas A. Vitanza, Joshua E. Allen, Sharon L. Gardner
Publikováno v:
Journal of Clinical Oncology. 40:TPS2082-TPS2082
TPS2082 Background: H3 K27M-mutant diffuse midline glioma is a universally fatal malignancy primarily affecting children and young adults; while radiotherapy (RT) provides transient benefit, no effective systemic therapy is currently available. ONC20