Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sharon L, Salmon"'
Autor:
Rae D. Record Ritchie, PhD, Sharon L. Salmon, BSc, Michael C. Hiles, PhD, Dennis W. Metzger, PhD
Publikováno v:
Surgery Open Science, Vol 10, Iss , Pp 83-90 (2022)
Background: Clinically useful biomaterials are derived from xenogeneic extracellular matrices, but extensive processes often used to remove all residual DNA are detrimental to their proper biological function. We hypothesized that deliberate and repe
Externí odkaz:
https://doaj.org/article/8e28ccf4173b4955ba0438c11f1faa4f
Autor:
Tarani Kanta Barman, Amit K. Singh, Jesse L. Bonin, Tanvir Noor Nafiz, Sharon L. Salmon, Dennis W. Metzger
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
Secondary infections are frequent complications of viral respiratory infections, but the potential consequence of SARS-CoV-2 coinfection with common pulmonary pathogens is poorly understood. We report that coinfection of human ACE2–transgenic mice
Externí odkaz:
https://doaj.org/article/03ba45e91b9c4372a8c1ea9c4ab5432f
Autor:
Tarani Kanta Barman, Rachael Racine, Jesse L Bonin, Danielle Califano, Sharon L Salmon, Dennis W Metzger
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009405 (2021)
Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections following influenza, but the relative roles of type-I versus type-II IFN remain poorly unders
Externí odkaz:
https://doaj.org/article/330e733cd7554e13bdb11b1f3afaac28
Autor:
Sean Roberts, Sharon L. Salmon, Donald J. Steiner, Clare M. Williams, Dennis W. Metzger, Yoichi Furuya
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Fatal outcomes following influenza infection are often associated with secondary bacterial infections. Allergic airway disease (AAD) is known to influence severe complications from respiratory infections, and yet the mechanistic effect of AA
Externí odkaz:
https://doaj.org/article/9dd5786ecf724d57874c90af930d89a7
Autor:
Sean Roberts, Clare M. Williams, Sharon L. Salmon, Jesse L. Bonin, Dennis W. Metzger, Yoichi Furuya
Publikováno v:
Vaccines, Vol 7, Iss 4, p 146 (2019)
Secondary bacterial pneumonia is responsible for significant morbidity and mortality during seasonal and pandemic influenza. Due to the unpredictability of influenza A virus evolution and the time-consuming process of manufacturing strain-specific in
Externí odkaz:
https://doaj.org/article/cc68d25350c148e0acb6948fa6b059b1
Autor:
Tarani Kanta Barman, Victor C. Huber, Jesse L. Bonin, Danielle Califano, Sharon L. Salmon, Andrew N. J. McKenzie, Dennis W. Metzger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(8)
SignificanceThe regulation of functional immune cell plasticity is poorly understood. Host environmental cues are critical, but the possible influence of pathogen-derived virulence factors has not been described. We have used reverse-engineered influ
Autor:
Yoichi Furuya, Andrea K M Furuya, Sean Roberts, Alan M Sanfilippo, Sharon L Salmon, Dennis W Metzger
Publikováno v:
PLoS Pathogens, Vol 11, Iss 9, p e1005180 (2015)
Asthma is believed to be a risk factor for influenza infection, however little experimental evidence exists to directly demonstrate the impact of asthma on susceptibility to influenza infection. Using a mouse model, we now report that asthmatic mice
Externí odkaz:
https://doaj.org/article/25588618c33c4cba9a685d60dcbf4d46
Autor:
Anthony L Steichen, Tanner J Simonson, Sharon L Salmon, Dennis W Metzger, Bibhuti B Mishra, Jyotika Sharma
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123573 (2015)
Sepsis is a complex immune disorder that is characterized by systemic hyperinflammation. Alarmins, which are multifunctional endogenous factors, have been implicated in exacerbation of inflammation in many immune disorders including sepsis. Here we s
Externí odkaz:
https://doaj.org/article/c0a58db273fa444fad022f7022430721
Autor:
Rachael Racine, Jesse L. Bonin, Sharon L. Salmon, Tarani Kanta Barman, Dennis W. Metzger, Danielle Califano
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009405 (2021)
PLoS Pathogens
PLoS Pathogens
Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections following influenza, but the relative roles of type-I versus type-II IFN remain poorly unders
Autor:
Lester Kobzik, Sharon L. Salmon, Glen M. DeLoid, Dennis W. Metzger, David Gregory, Igor Kramnik
Publikováno v:
FEBS Lett
Intracellular pathogens affect diverse host cellular defence and metabolic pathways. Here, we used infection with Francisella tularensis to identify SON DNA binding protein as a central determinant of macrophage activities. RNAi knockdown of SON incr