Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Sharon L, Hunt"'
Autor:
Mohamad Houry, Zahra Younoszai, Zobair M. Younossi, Sharon L. Hunt, Zachary Goodman, Otgonsuren Munkhzul, Ali Moosvi, Siddharth Hariharan, Li Zheng, Fanny Monge, Thomas Jeffers, Yousef Fazel, Azza Karrar
Publikováno v:
Medicine
The human leukocyte antigen (HLA) genes may play a role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and its progressive form, non-alcoholic steatohepatitis (NASH). The aim of this study was to assess the association of HLA class
Autor:
Michael P. Curry, Maria Stepanova, Robert S. Brown, Sharon L. Hunt, Jacqueline G. O'Leary, Michael Charlton, Zobair M. Younossi
Publikováno v:
The Lancet Gastroenterology & Hepatology. 1:122-132
Summary Background Hepatitis C virus (HCV) treatment regimens with direct-acting antivirals have not been extensively studied in patients with decompensated cirrhosis. We assessed patient-reported outcomes (PROs) in patients with decompensated cirrho
Autor:
Zobair M. Younossi, Matthew Paulson, Paul J. Clark, Maria Stepanova, Francesco Negro, Qinghua Song, John G. McHutchison, Luisa M. Stamm, Michael Estep, Diana M. Brainard, G. Mani Subramanian, Sharon L. Hunt, Keyur Patel
Publikováno v:
Journal of Hepatology, Vol. 64, No 1 (2016) pp. 29-36
Hepatitis C virus (HCV) modulates host lipid metabolism for its replication and lifecycle. Our aims were to assess changes in the serum lipid and distal (post-squalene) cholesterol biosynthesis metabolite profile of HCV genotypes (GT) 2 and 3 patient
Autor:
Zobair M. Younossi, Sharon L. Hunt, Stefan Zeuzem, Linda Henry, Patrick Marcellin, Maria Stepanova, Nezam H. Afdhal, Kris V. Kowdley
Publikováno v:
Journal of Hepatology. 63:337-345
Background & Aims New interferon-free anti-HCV regimens are highly efficacious with a favorable safety profile. We assessed health-related quality of life (HRQL) and work productivity in patients with different stages of hepatic fibrosis treated with
Autor:
Azza Karrar, Fanny Monge, Zobair M. Younossi, Zahra Younoszai, Elena Younossi, Li Zheng, Sneha Lingam, Lakshmi Alaparthi, Maria Stepanova, Khatera S. Malik, Sharon L. Hunt, Zachary Goodman
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:900-908
Background and Aim A significant number of autoantibodies have been reported in patients with non-alcoholic fatty liver disease (NAFLD) patients. In the present study, our aim was to assess the role of disease and cell-specific antibodies, namely ant
Autor:
Massimo Puoti, Maria Stepanova, Susanna Naggie, Sharon L. Hunt, Zobair M. Younossi, Chloe Orkin, Mark S. Sulkowski
Publikováno v:
Journal of Infectious Diseases. 212:367-377
Background. Sofosbuvir-containing regimens have been approved for treatment of hepatitis C virus (HCV) infection in human immunodeficiency virus (HIV)-infected patients. We assessed the effect of treatment with sofosbuvir and ribavirin on patient-rep
Autor:
Michael Estep, Elena Younossi, Linda Henry, Nayeem Hossain, Sharon L. Hunt, Zachary Goodman, Yun Fang, Zobair M. Younossi, Spencer Frost, Munkhzul Otgonsuren
Publikováno v:
Journal of Gastroenterology and Hepatology. 29:2006-2013
Background and Aim Non-alcoholic steatohepatitis (NASH) is the progressive form of non-alcoholic fatty liver disease (NAFLD). A liver biopsy is considered the “gold standard” for diagnosing/staging NASH. Identification of NAFLD/NASH using non-inv
Autor:
Munkhzul Otgonsuren, Zobair M. Younossi, Alita Mishra, Sharon L. Hunt, Chapy Venkatesan, Linda Henry
Publikováno v:
Digestive Diseases and Sciences. 60:320-332
The prevalence of advanced liver disease and its complications may be on the rise within the Medicare population. The study aim was trend assessment for prevalence, mortality and resource utilization of patients with advanced liver disease. A retrosp
Autor:
Spencer Frost, Maria Stepanova, Shirley Kalwaney, Zobair M. Younossi, S. Clement, Sammy Saab, Linda Henry, Sharon L. Hunt
Publikováno v:
Alimentary Pharmacology & Therapeutics. 40:686-694
Summary Background Type 2 diabetes is known to negatively impact the outcome of chronic liver disease. Aim To evaluate the impact of diabetes on the outcomes of liver transplants (LT). Methods Study cohort included adults (>18 years) who received LT
Autor:
Zahra Younoszai, Bryan Raybuck, E. Elsheikh, Munkhzul Otgonsuren, Sharon L. Hunt, Zobair M. Younossi
Publikováno v:
Journal of Gastroenterology and Hepatology. 29:1528-1534
Background Non-alcoholic fatty liver disease (NAFLD) has been associated with coronary artery disease (CAD) and cardiac-related mortality. Aim To assess the association between endothelial dysfunction markers (Endocan, high mobility group box 1 [HMGB