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Autor:
Rodger J. Winn, Anthony J. Scalzo, Beth Bready, David R. Close, Richard Pazdur, James E. Brandof, Sharon Kolbye
Publikováno v:
Investigational New Drugs. 12:263-265
Piroxantrone, a synthetic intercalating agent, was studied in patients with advanced, measurable gastric adenocarcinoma who had not received prior chemotherapy. The starting piroxantrone dose was 150 mg/m2 given intravenously over 1 hour on day 1 and