Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sharon J. Sequeira"'
Autor:
Deirdre A. Nelson, Charles Manhardt, Vidya Kamath, Yunxia Sui, Alberto Santamaria-Pang, Ali Can, Musodiq Bello, Alex Corwin, Sean R. Dinn, Michael Lazare, Elise M. Gervais, Sharon J. Sequeira, Sarah B. Peters, Fiona Ginty, Michael J. Gerdes, Melinda Larsen
Publikováno v:
Biology Open, Vol 2, Iss 5, Pp 439-447 (2013)
Summary Epithelial organ morphogenesis involves reciprocal interactions between epithelial and mesenchymal cell types to balance progenitor cell retention and expansion with cell differentiation for evolution of tissue architecture. Underlying subman
Externí odkaz:
https://doaj.org/article/f330b71b1b6944f7b3adfcb8fde714e6
Autor:
Stanley Abraham, Janice H. Kim, Sharon J. Sequeira, Elise M. Gervais, Melinda Larsen, Daniel Leonard, Kara A. DeSantis, Weihao Wang
Publikováno v:
Organogenesis. 12(4)
The salivary epithelium initiates as a solid mass of epithelial cells that are organized into a primary bud that undergoes morphogenesis and differentiation to yield bilayered acini consisting of interior secretory acinar cells that are surrounded by
Autor:
Michael Lazare, Fiona Ginty, Vidya Pundalik Kamath, Alberto Santamaria-Pang, Deirdre A. Nelson, Ali Can, Corwin Alex D, Sarah B. Peters, Melinda Larsen, Charles Manhardt, Elise M. Gervais, Musodiq Bello, Sharon J. Sequeira, Yunxia Sui, Sean Richard Dinn, Michael J. Gerdes
Publikováno v:
Biology Open
Biology Open, Vol 2, Iss 5, Pp 439-447 (2013)
Biology Open, Vol 2, Iss 5, Pp 439-447 (2013)
Summary Epithelial organ morphogenesis involves reciprocal interactions between epithelial and mesenchymal cell types to balance progenitor cell retention and expansion with cell differentiation for evolution of tissue architecture. Underlying subman
Autor:
David A. Soscia, James Castracane, Melinda Larsen, Riffard Jean-Gilles, Shraddha I. Cantara, Sharon J. Sequeira
Publikováno v:
Biomaterials. 33:8372-8382
Epithelial cell types typically lose apicobasal polarity when cultured on 2D substrates, but apicobasal polarity is required for directional secretion by secretory cells, such as salivary gland acinar cells. We cultured salivary gland epithelial cell
Autor:
David A. Soscia, Sharon J. Sequeira, Kavitha Jayarathanam, Melinda Larsen, Shraddha I. Cantara, James Castracane, Robert A. Schramm
There is a need for an artificial salivary gland as a long-term remedy for patients suffering from salivary hypofunction, a leading cause of chronic xerostomia (dry mouth). Current salivary gland tissue engineering approaches are limited in that they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2a5778c334e79c4621dc143ec84829
https://europepmc.org/articles/PMC3755621/
https://europepmc.org/articles/PMC3755621/
Publikováno v:
Journal of Visualized Experiments.
Branching morphogenesis occurs during the development of many organs, and the embryonic mouse submandibular gland (SMG) is a classical model for the study of branching morphogenesis. In the developing SMG, this process involves iterative steps of epi
Autor:
Susan E. LaFlamme, Savitha Sambandamoorthy, Kevin Pumiglia, Bethsaida Nieves, Shomita S. Mathew, Melinda Larsen, Sharon J. Sequeira
Publikováno v:
Journal of Cell Science.
Cytokinesis is the final stage in cell division. Although integrins can regulate cytokinesis, the mechanisms involved are not fully understood. In this study, we demonstrate that integrin-regulated ERK (extracellular signal-related kinase) and RSK (p
Autor:
David A. Soscia, Basak Oztan, Riffard Jean-Gilles, Aaron P. Mosier, Bülent Yener, James Castracane, Nathaniel C. Cady, Melinda Larsen, Sharon J. Sequeira, Anand Gadre
Publikováno v:
Biomaterials. 33(11)
Nanofiber scaffolds have been useful for engineering tissues derived from mesenchymal cells, but few studies have investigated their applicability for epithelial cell-derived tissues. In this study, we generated nanofiber (250 nm) or microfiber (1200
Autor:
Michael Melfi, Melinda Larsen, James Castracane, Riffard Jean-Gilles, Sharon J. Sequeira, Anand Gadre, David A. Soscia
Publikováno v:
Journal of Nanotechnology in Engineering and Medicine. 1
Electrospun nanofibers have been utilized in many biomedical applications as biomimetics of extracellular matrix proteins that promote self-organization of cells into 3D tissue constructs. As progress toward an artificial salivary gland tissue constr
Publikováno v:
Frontiers of oral biology. 14
The interstitial extracellular matrix (ECM) and epithelial-cell associated basement membrane (BM) play critical roles in the morphogenesis and differentiation of developing salivary glands. Early studies used ex vivo organ culture and tissue recombin