Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sharon J. Feng"'
Autor:
Beeke Wienert, David N. Nguyen, Alexis Guenther, Sharon J. Feng, Melissa N. Locke, Stacia K. Wyman, Jiyung Shin, Katelynn R. Kazane, Georgia L. Gregory, Matthew A. M. Carter, Francis Wright, Bruce R. Conklin, Alex Marson, Chris D. Richardson, Jacob E. Corn
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Altering cellular responses to double-strand breaks in DNA could rebalance CRISPRediting outcomes. Here, the authors use a pooled CRISPR screen to identify inhibition of CDC7 as a strategy to improve HDR outcomes.
Externí odkaz:
https://doaj.org/article/6ea294e461964f21b3fa07be064041d4
Autor:
Stephen Leong, Sharon J. Feng, Aykut Aksit, Elizabeth S. Olson, Jeffrey W. Kysar, Anil K. Lalwani
Publikováno v:
Otology & Neurotology. 44:513-519
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c26105dff4181b0129903b1cd63f4740
https://doi.org/10.1097/mao.0000000000003845
https://doi.org/10.1097/mao.0000000000003845
Publikováno v:
Journal of clinical medicine. 11(18)
Objectives: Precision medicine for inner ear disorders has seen significant advances in recent years. However, unreliable access to the inner ear has impeded diagnostics and therapeutic delivery. The purpose of this review is to describe the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e0f73598d4b6ec9fe00c228d666bcb
https://pubmed.ncbi.nlm.nih.gov/36143121
https://pubmed.ncbi.nlm.nih.gov/36143121
Autor:
Stephen Leong, Aykut Aksit, Betsy Szeto, Sharon J. Feng, Xiang Ji, Rajesh K. Soni, Elizabeth S. Olson, Jeffrey W. Kysar, Anil K. Lalwani
Publikováno v:
Hearing Research. 432:108739
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9298cc424452e323e1955d9bea76046
https://doi.org/10.1016/j.heares.2023.108739
https://doi.org/10.1016/j.heares.2023.108739
Autor:
Alexis Guenther, Francis Wright, Katelynn R. Kazane, Sharon J. Feng, Matthew Carter, Jiyung Shin, Jacob E. Corn, David N. Nguyen, Alexander Marson, Melissa N. Locke, Beeke Wienert, Bruce R. Conklin, Stacia K. Wyman, Christopher D. Richardson, Georgia L. Gregory
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, 11 (1)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications, 11 (1)
Nature Communications
Nature communications, vol 11, iss 1
Repair of double strand DNA breaks (DSBs) can result in gene disruption or gene modification via homology directed repair (HDR) from donor DNA. Altering cellular responses to DSBs may rebalance editing outcomes towards HDR and away from other repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e530bb12790f0bbfa3ab639984899f7c
https://doaj.org/article/6ea294e461964f21b3fa07be064041d4
https://doaj.org/article/6ea294e461964f21b3fa07be064041d4
Autor:
Erik Nohr, Helio A. Costa, Carol D. Jones, Eula Fung, Shirley Sutton, Linda Gojenola, James L. Zehnder, Carlos Bustamante, Hongbo Zhu, Christian A. Kunder, Sharon J. Feng
RNA sequencing is emerging as a powerful technique to detect a diverse array of fusions in human neoplasia, but few clinically validated assays have been described to date. We designed and validated a hybrid-capture RNAseq assay for FFPE tissue (Fusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0e1ff636bf278e0803848865469836
https://doi.org/10.1101/870634
https://doi.org/10.1101/870634
Autor:
Sharon J. Feng, Stacia K. Wyman, Katelynn R. Kazane, Alexander Marson, Melissa N. Locke, Christopher D. Richardson, Jacob E. Corn, David N. Nguyen, Beeke Wienert
Repair of double strand DNA breaks (DSBs) can result in gene disruption or precise gene modification via homology directed repair (HDR) from a templating donor DNA. During genome editing, altering cellular responses to DSBs may be an effective strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a8569ed561bddca06cc44dcf01e54f
https://doi.org/10.1101/500462
https://doi.org/10.1101/500462
Autor:
Nicholas L. Bray, Katelynn R. Kazane, Stephen N. Floor, Jacob E. Corn, Christopher D. Richardson, Sharon J. Feng, Axel J. Schäfer, Elena Zelin
Publikováno v:
Nature genetics. 50(8)
CRISPR–Cas genome editing creates targeted DNA double-strand breaks (DSBs) that are processed by cellular repair pathways, including the incorporation of exogenous DNA via single-strand template repair (SSTR). To determine the genetic basis of SSTR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b62f9506cab75e0dc5da86ef59e458
https://pubmed.ncbi.nlm.nih.gov/30054595
https://pubmed.ncbi.nlm.nih.gov/30054595
Autor:
Axel J. Schaefer, Stephen N. Floor, Christopher D. Richardson, Jacob E. Corn, Nicholas L. Bray, Sharon J. Feng, Katelynn R. Kazane
CRISPR-Cas9 genome editing creates targeted double strand breaks (DSBs) in eukaryotic cells that are processed by cellular DNA repair pathways. Co-administration of single stranded oligonucleotide donor DNA (ssODN) during editing can result in high-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eba775a98084c7f4d9e3b9519f4a0a9
https://doi.org/10.1101/136028
https://doi.org/10.1101/136028