Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sharon J. Archer"'
Autor:
Zhongren J. Wu, Daniel M. Camac, Peter J. Domaille, Zelda R. Wasserman, Sharon J. Archer, Lawrence J. Mersinger, Charles A. Kettner, Christopher J. Rizzo, Marina Bukhtiyarova, Sharada Jagannathan, Neil A. Farrow
Publikováno v:
Chemistry & Biology. 9(1):79-92
NMR spectroscopy was used to characterize the hepatitis C virus (HCV) NS3 protease in a complex with the 24 residue peptide cofactor from NS4A and a boronic acid inhibitor, Ac-Asp-Glu-Val-Val-Pro-boroAlg-OH. Secondary-structure information, NOE const
Publikováno v:
FEBS Letters. 337:145-151
The multifunctional protein profilin is one of the most abundant proteins in the cytoplasm and is thought to regulate actin assembly and the phosphoinositide signaling pathway. Profilin binds to several different ligands including actin, poly-l-proli
Publikováno v:
Journal of Magnetic Resonance (1969). 97:602-606
Recently Bax and colleagues ( 1) have shown that one avoids the problem of baseline distortion when acquiring complex data by using a sampling delay of one-half the dwell time. In addition, aliased signals, that lie outside the spectral window, are e
Publikováno v:
Journal of Magnetic Resonance (1969). 95:636-641
Values of ’ 5N‘H spin-spin coupling constants can be measured in a quantitative manner by recording ‘H‘H TOCSY /HOHAHA or NOESY spectra of a 15N-enriched protein in the absence of 15N decoupling (I ). Although this technique is elegant and po
Publikováno v:
Biophysical Journal. 60:389-398
Two spin-labeled derivatives of the ion conductive peptide alamethicin were synthesized and used to examine its binding and state of aggregation. One derivative was spin labeled at the C-terminus and the other, a leucine analogue, was spin labeled at
Autor:
Sharon J. Archer, David S. Cafiso
Publikováno v:
Biophysical Journal. 60:380-388
The ion currents induced by alamethicin were investigated in unilamellar vesicles using electron paramagnetic resonance probe techniques. The peptide induced currents were examined as a function of the membrane bound peptide concentration, and as a f
Autor:
Anita B. Roberts, Monica L.-S. Tsang, Sharon J. Archer, Su Wen Qian, Roger C. Lucas, Andrew P. Hinck, James A. Weatherbee, Michael B. Sporn, Dennis A. Torchia, Jeff Wenker, Bo Ling Zhang
Publikováno v:
Biochemistry. 35(26)
The three-dimensional solution structure of human transforming growth factor beta 1 (TGF-beta 1) has been determined using multinuclear magnetic resonance spectroscopy and a hybrid distance geometry/ simulated annealing algorithm. It represents one o
Publisher Summary Isotopic enrichment has made nuclear magnetic resonance (NMR) amenable to larger proteins and has proven particularly powerful for studying proteins, ligands, and protein-ligand complexes in solution. NMR spectroscopy of 13 C, 15 N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0130efcf7d33a804f73c1bf652bfdc5
https://doi.org/10.1016/s0065-7743(08)60469-8
https://doi.org/10.1016/s0065-7743(08)60469-8
Publikováno v:
Biochemistry. 32(26)
The protein profilin binds to both actin and the head groups of poly)phosphoinositide)s and may regulate both actin assembly and the phosphoinositide signaling pathway. As a first step in understanding the activity of profilin at the molecular level,
Autor:
Ogawa Y, Zheng Bl, Monica L.-S. Tsang, Sharon J. Archer, Piez Ka, Roger C. Lucas, Michael B. Sporn, Ad Bax, James A. Weatherbee, Anita B. Roberts
Publikováno v:
Biochemistry. 32(4)
The transforming growth factor 8s are a homologous family of multifunctional cytokines that regulate cell growth and differentiation. As a prelude to studies of the solution structure and dynamics of TGF-81, we report virtually complete assignment of