Zobrazeno 1 - 10 of 149 pro vyhledávání: '"Sharon J Pitteri"'
1
Akademický článek
AZGP1 deficiency promotes angiogenesis in prostate cancer
Autor: Ru M. Wen, Zhengyuan Qiu, G. Edward W. Marti, Eric E. Peterson, Fernando Jose Garcia Marques, Abel Bermudez, Yi Wei, Rosalie Nolley, Nathan Lam, Alex LaPat Polasko, Chun-Lung Chiu, Dalin Zhang, Sanghee Cho, Grigorios Marios Karageorgos, Elizabeth McDonough, Chrystal Chadwick, Fiona Ginty, Kyeong Joo Jung, Raghu Machiraju, Parag Mallick, Laura Crowley, Jonathan R. Pollack, Hongjuan Zhao, Sharon J. Pitteri, James D. Brooks
Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Loss of AZGP1 expression is a biomarker associated with progression to castration resistance, development of metastasis, and poor disease-specific survival in prostate cancer. However, high expression of AZGP1 cells in prostate ca
Externí odkaz: https://doaj.org/article/5a28bfe2f761406aa6383b764b9fb5d0
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2
Akademický článek
Identification and characterization of intact glycopeptides in human urine
Autor: Fernando Garcia-Marques, Keely Fuller, Abel Bermudez, Nikhiya Shamsher, Hongjuan Zhao, James D. Brooks, Mark R. Flory, Sharon J. Pitteri
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Glycoproteins in urine have the potential to provide a rich class of informative molecules for studying human health and disease. Despite this promise, the urine glycoproteome has been largely uncharacterized. Here, we present the analysis o
Externí odkaz: https://doaj.org/article/a59c996315e54c0a8cea97c2a56c91bd
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3
Akademický článek
Plasma proteome profiles associated with inflammation, angiogenesis, and cancer.
Autor: Karen S Kelly-Spratt, Sharon J Pitteri, Kay E Gurley, Denny Liggitt, Alice Chin, Jacob Kennedy, Chee-Hong Wong, Qing Zhang, Tina Busald Buson, Hong Wang, Samir M Hanash, Christopher J Kemp
Publikováno v: PLoS ONE, Vol 6, Iss 5, p e19721 (2011)
Tumor development is accompanied by a complex host systemic response, which includes inflammatory and angiogenic reactions. Both tumor-derived and systemic response proteins are detected in plasma from cancer patients. However, given their non-specif
Externí odkaz: https://doaj.org/article/ca0f0a69bff64f8fbe055b6d96b1ab09
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4
Akademický článek
Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery.
Autor: Sharon J Pitteri, Lellean JeBailey, Vitor M Faça, Jason D Thorpe, Melissa A Silva, Reneé C Ireton, Marc B Horton, Hong Wang, Liese C Pruitt, Qing Zhang, Kuang H Cheng, Nicole Urban, Samir M Hanash, Daniela M Dinulescu
Publikováno v: PLoS ONE, Vol 4, Iss 11, p e7916 (2009)
BACKGROUND:The complexity of the human plasma proteome represents a substantial challenge for biomarker discovery. Proteomic analysis of genetically engineered mouse models of cancer and isolated cancer cells and cell lines provide alternative method
Externí odkaz: https://doaj.org/article/93e2936741dc44f28aad14c4268b509d
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5
Akademický článek
A mouse to human search for plasma proteome changes associated with pancreatic tumor development.
Autor: Vitor M Faca, Kenneth S Song, Hong Wang, Qing Zhang, Alexei L Krasnoselsky, Lisa F Newcomb, Ruben R Plentz, Sushma Gurumurthy, Mark S Redston, Sharon J Pitteri, Sandra R Pereira-Faca, Renee C Ireton, Hiroyuki Katayama, Veronika Glukhova, Douglas Phanstiel, Dean E Brenner, Michelle A Anderson, David Misek, Nathalie Scholler, Nicole D Urban, Matt J Barnett, Cim Edelstein, Gary E Goodman, Mark D Thornquist, Martin W McIntosh, Ronald A DePinho, Nabeel Bardeesy, Samir M Hanash
Publikováno v: PLoS Medicine, Vol 5, Iss 6, p e123 (2008)
The complexity and heterogeneity of the human plasma proteome have presented significant challenges in the identification of protein changes associated with tumor development. Refined genetically engineered mouse (GEM) models of human cancer have bee
Externí odkaz: https://doaj.org/article/d24da75bd6e447fd91e328ee33f09d06
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6
Akademický článek
Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains.
Autor: Vitor M Faça, Aviva P Ventura, Mathew P Fitzgibbon, Sandra R Pereira-Faça, Sharon J Pitteri, Ann E Green, Renee C Ireton, Qing Zhang, Hong Wang, Kathy C O'Briant, Charles W Drescher, Michèl Schummer, Martin W McIntosh, Beatrice S Knudsen, Samir M Hanash
Publikováno v: PLoS ONE, Vol 3, Iss 6, p e2425 (2008)
BACKGROUND: Elucidation of the repertoire of secreted and cell surface proteins of tumor cells is relevant to molecular diagnostics, tumor imaging and targeted therapies. We have characterized the cell surface proteome and the proteins released into
Externí odkaz: https://doaj.org/article/4408807a7362412ebc75cf18ff14a7a6
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7
Akademický článek
Integrated transcriptome-proteome analyses of human stem cells reveal source-dependent differences in their regenerative signature
Autor: Abantika Ganguly, Ganesh Swaminathan, Fernando Garcia-Marques, Shobha Regmi, Reza Yarani, Rosita Primavera, Shashank Chetty, Abel Bermudez, Sharon J. Pitteri, Avnesh S. Thakor
Publikováno v: Stem Cell Reports, Vol 18, Iss 1, Pp 190-204 (2023)
Summary: Mesenchymal stem cells (MSCs) are gaining increasing prominence as an effective regenerative cellular therapy. However, ensuring consistent and reliable effects across clinical populations has proved to be challenging. In part, this can be a
Externí odkaz: https://doaj.org/article/d2c56875fa9044f5a1d84f044a7b1d8b
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