Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sharon J Gardiner"'
Autor:
Sharon J Gardiner, Philip G Drennan, Ronald Begg, Mei Zhang, Jared K Green, Heather L Isenman, Richard J Everts, Stephen T Chambers, Evan J Begg
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199370 (2018)
It is usually recommended that flucloxacillin is given on an empty stomach. The aim of this study was to compare total and free flucloxacillin concentrations after oral flucloxacillin, given with and without food, based on contemporary pharmacokineti
Externí odkaz:
https://doaj.org/article/ed5476a8638c4f73b05e60bf8a057552
Autor:
Stephen T. Chambers, Mei Zhang, Ronald Begg, Richard J. Everts, John D. Turnidge, Sharon J. Gardiner, Evan J. Begg
Publikováno v:
Journal of Infection. 83:182-189
Objectives: We evaluated the effects of probenecid on the Pharmaco Kinetics (PK) and pharmacodynamics (PD) of oral cephalexin in healthy volunteers. Methods: Cephalexin 1000 mg was administered orally to 11 healthy volunteers following a standardized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179b1ddeb3fc43ee945ed98cb4e61774
https://doi.org/10.1016/j.jinf.2021.05.037
https://doi.org/10.1016/j.jinf.2021.05.037
Autor:
Simon C. Dalton, Qian Yi Chuah, Paul K. L. Chin, Niall Hamilton, Sharon J. Gardiner, Sarah Metcalf
Publikováno v:
ACI Open. :e119-e125
Objectives The aim was to conduct a pilot study to determine staff resource requirements for an antimicrobial stewardship (AMS) ward round informed by electronic prescriptions, and the number of restricted antimicrobial prescriptions that would promp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb316cd73ebf5f23e9fb595be16bf98d
https://doi.org/10.1055/s-0040-1716749
https://doi.org/10.1055/s-0040-1716749
Autor:
Carl M. J. Kirkpatrick, Stephen T. Chambers, Jared Green, Richard J. Everts, Sarah Metcalf, Sharon J. Gardiner, Philip G. Drennan, Mei Zhang
Publikováno v:
British journal of clinical pharmacologyREFERENCES. 87(12)
Oral flucloxacillin may be coadministered with probenecid to reduce flucloxacillin clearance and increase attainment of pharmacokinetic-pharmacodynamic (PK/PD) targets. The aims of this study were to develop a population PK model of free flucloxacill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93401b5047809fd76e63018e6b3959b0
https://pubmed.ncbi.nlm.nih.gov/33963595
https://pubmed.ncbi.nlm.nih.gov/33963595
Autor:
Jared Green, Richard J. Everts, Sharon J. Gardiner, Mei Zhang, Sarah Metcalf, Philip G. Drennan, Stephen T. Chambers, Carl M. J. Kirkpatrick
Aim Oral flucloxacillin may be co-administered with probenecid to increase flucloxacillin concentrations and increase attainment of pharmacokinetic-pharmacodynamic (PK-PD) targets. The aims of this study were to describe outcomes of patients treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a4fcd91df9fa53de8f2933c45381c50
https://doi.org/10.22541/au.160918776.69793790/v1
https://doi.org/10.22541/au.160918776.69793790/v1
Autor:
Sharon J, Gardiner, Ari B, Basevi, Niall L, Hamilton, Sarah Cl, Metcalf, Stephen T, Chambers, Stephen G, Withington, Paul K, Chin, Joshua T, Freeman, Simon C, Dalton
Publikováno v:
The New Zealand medical journal. 133(1525)
To determine the nature and appropriateness of antimicrobial prescribing in adult inpatients at Canterbury District Health Board (CDHB).Multidisciplinary teams collected clinical details for all adult inpatients on antimicrobial therapy at three CDHB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60cb3e73d70eb21d0729cb4dd0743eab
https://pubmed.ncbi.nlm.nih.gov/33223545
https://pubmed.ncbi.nlm.nih.gov/33223545
Publikováno v:
The New Zealand medical journal. 133(1512)
To assess a persuasive multimodel approach to decreasing unnecessary intravenous (IV) clarithromycin use for community-acquired pneumonia (CAP) in Canterbury District Health Board (CDHB) hospitals.In December 2013, CDHB guidelines for empiric treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db11cbdb5065283f943c93c373a6ea4e
https://pubmed.ncbi.nlm.nih.gov/32242175
https://pubmed.ncbi.nlm.nih.gov/32242175
Autor:
Paul K. L. Chin, Philip G. Drennan, Simon C. Dalton, Stephen T. Chambers, Sharon J. Gardiner, Mei Zhang, Evan J. Begg
Publikováno v:
British Journal of Clinical Pharmacology. 84:2311-2316
AIMS Flucloxacillin dosing may be guided by measurement of its total plasma concentrations. Flucloxacillin is highly protein bound with fraction unbound in plasma (fu ) of around 0.04 in healthy individuals. The utility of measuring unbound flucloxac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc454195fb6907443892add31779be09
https://doi.org/10.1111/bcp.13673
https://doi.org/10.1111/bcp.13673
Autor:
Simon C. Dalton, Sharon J. Gardiner, Philip G. Drennan, Sarah Metcalf, Ma Yi, Stephen T. Chambers, Madeleine Long, Paul K. L. Chin
Publikováno v:
International Journal of Antimicrobial Agents. 55:105972
Vancomycin continuous infusion (VCI) is used to treat serious Gram-positive infections in outpatients. This study was conducted to retrospectively investigate the rate of nephrotoxicity and associated risk factors in out-patients on VCI between May 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387ceba38785b94696d007d716a821f5
https://doi.org/10.1016/j.ijantimicag.2020.105972
https://doi.org/10.1016/j.ijantimicag.2020.105972
Publikováno v:
International journal of antimicrobial agents. 53(4)
We have evaluated the literature to review optimal dosing and monitoring of intravenous vancomycin in adults, in response to evolving understanding of targets associated with efficacy and toxicity. The area under the total concentration-time curve (0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b43b64c49dea0bd842264a2a1b6fba
https://pubmed.ncbi.nlm.nih.gov/30599240
https://pubmed.ncbi.nlm.nih.gov/30599240