Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sharon J Busby"'
Autor:
Eileen R. Mulvihill, Donna E. Prunkard, D. Rao, P Lioubin, L Halfpap, Cindy A. Sprecher, J Gambee, Mark D. Heipel, Sharon J Busby, Kumar A Ashok
Publikováno v:
Journal of Biological Chemistry. 266:15286-15292
We present evidence that over-expression of human plasminogen, the precursor to the serine protease plasmin, can be cytotoxic to mammalian cells. When an expression vector containing plasminogen cDNA is transfected into baby hamster kidney cells, the
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
The vitamin K-dependent plasma proteins demonstrate remarkable similarities in their structures: all have multiple domains in common and extensive homology is observed within many of these domains. In order to investigate the structure-function relat
Autor:
Sharon J. Busby, Ronald H. Reeder
Publikováno v:
Developmental biology. 91(2)
We have followed the fate of two components of extrachromosomal nucleoli, amplified ribosomal DNA (rDNA) and 7.5 kb precursor rRNA, during early embryogenesis of Xenopus laevis . Other workers have shown that the amount of amplified rDNA accumulated
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
We have investigated the effect of altering the leader sequence of human factor VII on its biological activity. Factor VII is a vitamin K-dependent blood coagulation protein whose activity depends on the presence of gamma-carboxyglutamic acid (gla) r
Autor:
Michael Joseph, Maggie Insley, Sharon J Busby, Richard G Woodbury, Laurel Halfpap, Kotoku Kurachi, Kathleen L. Berkner, Kumar A Ashok
Publikováno v:
Nature. 316(6025)
Factor IX is the precursor of a serine protease that functions in the intrinsic blood clotting pathway1. Deficiencies in this plasma glycoprotein result in haemophilia B (or Christmas disease) and occur in about 1 in 30,000 males2. Patients are curre
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
Factor IX, a plasma protein, plays a critical role in blood coagulation. The biological activity of factor IX as well as several other plasma proteins depends on the presence of gamma-carboxy glutamic acid (Gla) residues in their amino terminal regio
Publikováno v:
Fibrinolysis. 2:64