Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sharon Isern"'
Autor:
Nathan D. Grubaugh, Karthik Gangavarapu, Joshua Quick, Nathaniel L. Matteson, Jaqueline Goes De Jesus, Bradley J. Main, Amanda L. Tan, Lauren M. Paul, Doug E. Brackney, Saran Grewal, Nikos Gurfield, Koen K. A. Van Rompay, Sharon Isern, Scott F. Michael, Lark L. Coffey, Nicholas J. Loman, Kristian G. Andersen
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract How viruses evolve within hosts can dictate infection outcomes; however, reconstructing this process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to demonstrate how virus concentration, sequencing coverage, prime
Externí odkaz:
https://doaj.org/article/24ff68cedc704adfa9db1173d023ac4c
Autor:
Shee-Mei Lok, Joshua M Costin, Yancey M Hrobowski, Andrew R Hoffmann, Dawne K Rowe, Petra Kukkaro, Heather Holdaway, Paul Chipman, Krystal A Fontaine, Michael R Holbrook, Robert F Garry, Victor Kostyuchenko, William C Wimley, Sharon Isern, Michael G Rossmann, Scott F Michael
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50995 (2012)
Dengue virus infects approximately 100 million people annually, but there is no available therapeutic treatment. The mimetic peptide, DN59, consists of residues corresponding to the membrane interacting, amphipathic stem region of the dengue virus en
Externí odkaz:
https://doaj.org/article/bdc87599a35e4f68be5cecd625da32e3
Autor:
Joshua M Costin, Ekachai Jenwitheesuk, Shee-Mei Lok, Elizabeth Hunsperger, Kelly A Conrads, Krystal A Fontaine, Craig R Rees, Michael G Rossmann, Sharon Isern, Ram Samudrala, Scott F Michael
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 6, p e721 (2010)
Viral fusogenic envelope proteins are important targets for the development of inhibitors of viral entry. We report an approach for the computational design of peptide inhibitors of the dengue 2 virus (DENV-2) envelope (E) protein using high-resoluti
Externí odkaz:
https://doaj.org/article/f2a1eca4a9a5439db0bff740f5d6cbf3
Autor:
Amanda S. Graham, Catherine A. Pruszynski, Lawrence J. Hribar, David J. DeMay, Adriane N. Tambasco, Anne E. Hartley, Edsel M. Fussell, Scott F. Michael, Sharon Isern
Publikováno v:
Emerging Infectious Diseases, Vol 17, Iss 11, Pp 2074-2075 (2011)
Externí odkaz:
https://doaj.org/article/03994e4d2952425e9993fcb735166008
Autor:
Danielle A. Basore, Carolyn M. Barcellona, Thomas B. Jordan, Donna E. Crone, Sharon Isern, Scott F. Michael, Christopher Bystroff
The authors have withdrawn their manuscript as it was submitted and made public without the full consent of all the authors. Therefore, the authors do not wish this work to be cited as reference for the project. If you have any questions, please cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d6322e3c4b7e9444c3e82562b4089f5
https://doi.org/10.1101/2022.10.11.511616
https://doi.org/10.1101/2022.10.11.511616
Autor:
Sharon Isern, Onikepe A. Folarin, Philomena Eromon, Thiago Moreno L. Souza, Yasmine Rangel Vieira, Kimberly García, Christian B. Matranga, Douglas S. Kwon, Etienne Simon-Loriere, Shirlee Wohl, Ivette Lorenzana, Hayden C. Metsky, Patrick Brehio, Katherine J. Siddle, David K Yang, Scott F. Michael, Giselle Barbosa-Lima, Adrianne Gladden-Young, Leda Parham, Lauren M. Paul, Augustine Goba, Bjӧrn Corleis, Todd M. Allen, Andreas Gnirke, Pardis C. Sabeti, Scott Hennigan, Eva Harris, Jonathan A. Runstadler, Andrew Goldfarb, Lee Gehrke, Sandra Smole, Christian T. Happi, Amanda L Tan, Angel Balmaseda, Damien C. Tully, Anne Piantadosi, Fernando A. Bozza, Aaron E. Lin, Gregory D. Ebel, Daniel J. Park, Amber Carter, James Qu, Donald S. Grant, Ikponmwonsa Odia, Irene Bosch, Lisa E. Hensley, Kayla G. Barnes
Publikováno v:
Nature Biotechnology
Nature biotechnology
Nature biotechnology
Metagenomic sequencing has the potential to transform microbial detection and characterization, but new tools are needed to improve its sensitivity. Here we present CATCH, a computational method to enhance nucleic acid capture for enrichment of diver
Autor:
Jaqueline Goes de Jesus, Joshua Quick, Nathan D. Grubaugh, Bradley J. Main, Lark L. Coffey, Scott F. Michael, Doug E. Brackney, Kristian G. Andersen, Koen K. A. Van Rompay, Nikos Gurfield, Karthik Gangavarapu, Lauren M. Paul, Amanda L Tan, Nathaniel L. Matteson, Nicholas J. Loman, Sharon Isern, Saran Grewal
Publikováno v:
Genome Biology
Genome Biology, Vol 20, Iss 1, Pp 1-19 (2019)
Genome Biology, Vol 20, Iss 1, Pp 1-19 (2019)
How viruses evolves within hosts can dictate infection outcomes; however, accurately reconstructing this process is challenging from samples with low virus concentrations. We evaluated our highly multiplexed amplicon approach - PrimalSeq - to enrich
Autor:
Amanda L Tan, Matteson Nl, Glenn Oliveira, Scott F. Michael, Alexander Watts, Davidson H. Hamer, Sharon Isern, Chantal B.F. Vogels, Saraf S, Landis, Nathan D. Grubaugh, Marshall R. Cone, Karthik Gangavarapu, Andrea Morrison, Leah D Gillis, Andrew C. Cannons, Kristian G. Andersen, Diogo M. Magnani, Blake Scott, Rachel J. Oidtman, Danielle Stanek, Jason T. Ladner, Lichtenberger Pk, Jaclyn Kwal, Stryker I, Michael J. Ricciardi, Alex Perkins T, Lea Heberlein-Larson, Kamran Khan, Deepit Bhatia, Moritz U. G. Kraemer, Gustavo Palacios, David I. Watkins, Guy Baele, Stephen White, Aaron Hentoff, Edgar W. Kopp, Lauren Gardner
The ongoing Zika epidemic in the Americas has challenged public health surveillance, response, and control systems. Even as the epidemic appears to be near its end in the Americas, it is unclear whether substantial Zika virus transmission may still b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e0702d21a8a0ed3d024d51f811c4fd
https://doi.org/10.1101/496901
https://doi.org/10.1101/496901
Autor:
Jamie C. Gaitor, Richard E. Sykora, Arsalan Mirjafari, Samuel Minkowicz, Stephen T. Nestor, Yinghong Sheng, Manuel Sanchez Zayas, Lauran M. Paul, Sharon Isern, Scott F. Michael, Richard A. O'Brien, Forrest A. Edhegard
Publikováno v:
New Journal of Chemistry. 40:7795-7803
We demonstrate herein a facile synthesis of a series of highly-ordered low-melting protic ionic liquids with linear C16–C20 side chains identical to natural fatty acids, which were produced by the S-alkylation of the 2-mercapto-1-methylimidazole (m
Autor:
Scott F. Michael, Sharon Isern, John H. Connor, Michaela J. Schultz, Amanda L Tan, C.N. Gray, Horacio M. Frydman
Publikováno v:
mBio
mBio, Vol 9, Iss 3 (2018)
mBio, Vol 9, Iss 3, p e00738-18 (2018)
mBio, Vol 9, Iss 3 (2018)
mBio, Vol 9, Iss 3, p e00738-18 (2018)
Mosquito-transmitted viruses are spread globally and present a great risk to human health. Among the many approaches investigated to limit the diseases caused by these viruses are attempts to make mosquitos resistant to virus infection. Coinfection o