Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sharon Illenye"'
Publikováno v:
BioTechniques, Vol 35, Iss 4, Pp 796-807 (2003)
Although bacterial artificial chromosomes (BACs) provide a well-characterized resource for the analysis of large chromosomal domains, low transfection rates have proven a significant limitation for their use in cell culture models. Using TP53 BAC clo
Externí odkaz:
https://doaj.org/article/38563fb7c28b4fa889ce28d087a85805
Autor:
Sharon Illenye, Erika Currier, Maria C. Mendonça, Akshita Dutta, Giselle Saulnier Sholler, Jeffrey P. Bond, Marni A Slavik, Julie A. Dragon, Stephen S. Roberts
Publikováno v:
Journal of cancer therapeuticsresearch. 2
In this study, we investigated the cytotoxic effects of a broad-spectrum histone deacetylase (HDAC) inhibitor, PCI-24781, alone and in combination with the proteasome inhibitor bortezomib in neuroblastoma cell lines. The combination was shown to indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d6cdac41e70754c787f0f67cacf5db
https://pubmed.ncbi.nlm.nih.gov/25520806
https://pubmed.ncbi.nlm.nih.gov/25520806
Publikováno v:
BioTechniques. 35:796-807
Although bacterial artificial chromosomes (BACs) provide a well-characterized resource for the analysis of large chromosomal domains, low transfection rates have proven a significant limitation for their use in cell culture models. Using TP53 BAC clo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d14c6144e2ae108f3765b380001c494
https://doi.org/10.2144/03354rr02
https://doi.org/10.2144/03354rr02
Autor:
Sharon Illenye, Nicholas H. Heintz, Young-Chae Chang, Jonathan M. Gilbert, Emily Coonrod, William J. Montigny, Christopher R. Houchens
Publikováno v:
Nucleic Acids Research. 29:1982-1988
Experimental studies of complete mammalian genes and other genetic domains are impeded by the difficulty of introducing large DNA molecules into cells in culture. Previously we have shown that GST–Z2, a protein that contains three zinc fingers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c0ca90e9951954dfc4aaf38342dd94
https://doi.org/10.1093/nar/29.9.1982
https://doi.org/10.1093/nar/29.9.1982
Publikováno v:
Molecular and Cellular Biology. 21:1121-1131
In mammalian cells reiterated binding sites for Sp1 and two overlapping and inverted E2F sites at the transcription start site regulate the dhfr promoter during the cell growth cycle. Here we have examined the contributions of the dhfr Sp1 and E2F si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee471bb1708c271dcc93ac553aa6aea
https://doi.org/10.1128/mcb.21.4.1121-1131.2001
https://doi.org/10.1128/mcb.21.4.1121-1131.2001
Autor:
Nicholas H. Heintz, Sharon Illenye, Young-Chae Chang, Yun-Sik Lee, Kiyoshi Sawai, Hiroo Nakajima, Ikuya Fujiwara, Nobuko Honjo, Junji Magae, Kaname Saida, Tazuko Makiyama, Youji Mitsui, Naruhiko Mizuta
Publikováno v:
Oncogene. 19:4713-4720
E2F is a family of transcription factors which regulates cell cycle and apoptosis of mammalian cells. E2F-1-3 localize in the nucleus, and preferentially bind pRb, while E2F-4 and 5 have no nuclear localization signal and preferentially bind p107/p13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268c625b223f382328fe8efcc7c23c21
https://doi.org/10.1038/sj.onc.1203833
https://doi.org/10.1038/sj.onc.1203833
Autor:
Keiji Tanaka, T Tejima, Sharon Illenye, Nicholas H. Heintz, Junji Magae, Young-Chae Chang, Omura S, Youji Mitsui
Publikováno v:
Oncogene. 15:759-769
The transcription factors p53 and E2F-1 play important roles in the control of cell cycle progression. In transient transfection experiments, expression of E2F-1, other E2F family members, or p53 squelched transcription from cotransfected plasmids in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09f8644334a392171a73ed5db537b11
https://doi.org/10.1038/sj.onc.1201251
https://doi.org/10.1038/sj.onc.1201251
Autor:
Giselle L. Saulnier Sholler, Rakesh K. Singh, Sharon Illenye, Angelica M. DeMartino, Erika Currier, Takamaru Ashikaga, Karen Koto, Lee Dorf, Kyu Kwang Kim, Laurent Brard
Publikováno v:
Cancer biologytherapy. 11(12)
Patients diagnosed with high-risk neuroblastoma (NB), an extracranial solid tumor in children, have metastases and low survival (30%) despite aggressive multi-modal therapy. Therefore new therapies are urgently needed. We show significant in vitro an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab6073ad8d6f8af27033959f96ff5d2
https://pubmed.ncbi.nlm.nih.gov/21532338
https://pubmed.ncbi.nlm.nih.gov/21532338
Autor:
Takamaru Ashikaga, Kyu Kwang Kim, Giselle L. Saulnier Sholler, Sharon Illenye, Karen Koto, Jeff Bond, Marni A Slavik, Rakesh K. Singh, Pamela J. Lescault, Laurent Brard
Publikováno v:
International Journal of Oncology. 38
Medulloblastoma, a neuroectodermal tumor arising in the cerebellum, is the most common brain tumor found in children. We recently showed that nifurtimox induces production of reactive oxygen species (ROS) and subsequent apoptosis in neuroblastoma cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a004051a6490210850473206ed967569
https://doi.org/10.3892/ijo.2011.971
https://doi.org/10.3892/ijo.2011.971
Publikováno v:
Nucleic Acids Research. 20:3485-3494
The polymerase chain reaction (PCR) represents an alternative to the current methods for investigating DNA damage and repair in specific genomic segments. In theory, any DNA lesion which blocks Taq polymerase can be measured by this assay. We used qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9d80e7425d6c0227519f1fb93c57cc
https://doi.org/10.1093/nar/20.13.3485
https://doi.org/10.1093/nar/20.13.3485