Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sharon Hom"'
Autor:
Colin L. Willis, Jeffrey J. Lochhead, Carolyn A. Quigley, William D. Staatz, Gwen McCaffrey, Thomas P. Davis, Nicole Nametz, Sharon Hom
Publikováno v:
Journal of Neurochemistry. 110:58-71
Hypoxic (low oxygen) and reperfusion (post-hypoxic reoxygenation) phases of stroke promote an increase in microvascular permeability at tight junctions (TJs) of the blood-brain barrier (BBB) that may lead to cerebral edema. To investigate the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381136868886742995ca2989354c4ff7
https://doi.org/10.1111/j.1471-4159.2009.06113.x
https://doi.org/10.1111/j.1471-4159.2009.06113.x
Publikováno v:
Brain Research. 1221:6-13
Previous studies by our group have shown that peripheral inflammatory insult, using the lambda-carrageenan inflammatory pain (CIP) model, induced alterations in the molecular and functional properties of the blood-brain barrier (BBB). The question re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf8bf7cc0b7e2e3a3253b3ccd8d86ef
https://doi.org/10.1016/j.brainres.2008.05.013
https://doi.org/10.1016/j.brainres.2008.05.013
Autor:
Brian T. Hawkins, Sharon Hom, Richard D. Egleton, Melissa A. Fleegal, Christopher R. Campos, Thomas P. Davis
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 292:R1881-R1892
Hypertension is involved in the exacerbation of stroke. It is unclear how blood-brain barrier (BBB) tight-junction (TJ) and ion transporter proteins critical for maintaining brain homeostasis contribute to cerebral infarction during hypertension deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15410d2aa944c12a63ef99da3c616f5
https://doi.org/10.1152/ajpregu.00761.2005
https://doi.org/10.1152/ajpregu.00761.2005
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 285:H2820-H2831
Cerebral microvessel endothelial cells that form the blood-brain barrier (BBB) have tight junctions (TJs) that are critical for maintaining brain homeostasis. The effects of initial reoxygenation after a hypoxic insult (H/R) on functional and molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a08a9e7d70a3bf5f18156058317fce
https://doi.org/10.1152/ajpheart.00589.2003
https://doi.org/10.1152/ajpheart.00589.2003
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 289(5)
The blood-brain barrier (BBB) is a metabolic and physiological barrier important for maintaining brain homeostasis. The aim of this study was to determine the role of PKC activation in BBB paracellular permeability changes induced by hypoxia and post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9614e7bc2bd4f9d992326f924c82a471
https://pubmed.ncbi.nlm.nih.gov/15994856
https://pubmed.ncbi.nlm.nih.gov/15994856
Autor:
Sharon Hom
Publikováno v:
Proceedings of the ASIL Annual Meeting. 89:165-167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79fe3984b08aba9985e2f2ac294e4ae2
https://doi.org/10.1017/s0272503700083981
https://doi.org/10.1017/s0272503700083981
Publikováno v:
Brain research. 890(1)
Pathological states (i.e. stroke, cardiac arrest) can lead to reduced blood flow to the brain potentially altering blood-brain barrier (BBB) permeability and regulatory transport functions. BBB disruption leads to increased cerebrovascular permeabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7f0bd2d177612010f8ab78c7432bb4
https://pubmed.ncbi.nlm.nih.gov/11164767
https://pubmed.ncbi.nlm.nih.gov/11164767
Publikováno v:
Peptides. 16(7)
Eight analogues of DYN A(1-11)-NH2 incorporating the nonhydrolyzable psi [CH2-NH] peptide bond surrogate were tested for their in vitro enzymatic stability in mouse brain homogenates. Results show that the Leu(5)-Arg6 and to a lesser extent the Arg(7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce21cd2e2f6d7fd9aede564fcf0b6a2b
https://pubmed.ncbi.nlm.nih.gov/8545241
https://pubmed.ncbi.nlm.nih.gov/8545241
Publikováno v:
Europe PubMed Central
Effects of inflammatory pain states on functional and molecular properties of the rat blood-brain barrier (BBB) were investigated. Inflammation was produced by subcutaneous injection of formalin, λ-carrageenan, or complete Freund's adjuvant (CFA) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e16872e6954ce8575eecc4685fd5202
http://europepmc.org/abstract/med/11179069
http://europepmc.org/abstract/med/11179069
