Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sharon Grehan"'
Autor:
Joseph B. Muhlestein, Sharon Grehan
Publikováno v:
Drugs in R&D
Background Chronic stable angina negatively affects quality of life (QoL). American College of Cardiology/American Heart Association guidelines highlight maintaining/restoring a level of activity, functional capacity, and QoL that is satisfactory to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aff8f71a9f868954bab9bbbe6e75e74
https://doi.org/10.1007/s40268-013-0026-4
https://doi.org/10.1007/s40268-013-0026-4
Publikováno v:
European Journal of Immunology. 27:2593-2599
An inflammatory response was induced in C57BL/6 mice using silver nitrate. Co-administration of a recombinant mouse interleukin-1 receptor antagonist (rmIL-1ra) significantly reduced the magnitude of hepatic induction of the mRNA specifying the serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae0d1a85776818a430be7649dd09b20
https://doi.org/10.1002/eji.1830271019
https://doi.org/10.1002/eji.1830271019
Autor:
Alexander S. Whitehead, Alexander Steinkasserer, Sharon Grehan, Clarissa M. Uhlar, Diana M. Steel
Publikováno v:
Journal of Immunological Methods. 203:123-130
A cytokine responsive construct, pGL2-SAA2pt, was generated by cloning the acute phase promoter of human serum amyloid A2 (SAA2) upstream of a luciferase reporter gene. The construct responds to the inflammatory mediators MoCM, IL-1 beta, TNF-alpha,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acaf1283e775f8bbbde525198fed8658
https://doi.org/10.1016/s0022-1759(96)00220-7
https://doi.org/10.1016/s0022-1759(96)00220-7
Publikováno v:
The Journal of investigative dermatology. 116(1)
A distal enhancer that specifies apolipoprotein E gene expression in the skin was identified and characterized by in situ hybridization in transgenic mice generated with constructs of the human apolipoprotein E/C-I/C-IV/C-II gene cluster. Transgene c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb19f5e9e94767785b00b4b6a3ce2d4
https://pubmed.ncbi.nlm.nih.gov/11168801
https://pubmed.ncbi.nlm.nih.gov/11168801
Two distal downstream enhancers controlling astrocyte expression of the human apolipoprotein E (apoE) gene in the brain were identified by analysis of transgenic mice generated with various constructs of the apoE/C-I/C-IV/C-II gene cluster. In wild-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d173f84ea98f0299b288cf48cc9a1c
https://europepmc.org/articles/PMC6762321/
https://europepmc.org/articles/PMC6762321/
Autor:
Sharon Grehan, Elizabeth Tse, John M. Taylor, Charles M. Allan, Shyh-Jen Shih, Cathal J. Moran
Publikováno v:
The Journal of biological chemistry. 275(41)
Two distal enhancers that specify apolipoprotein (apo) E gene expression in isolated macrophages and adipose tissue were identified in transgenic mice that were generated with constructs of the human apoE/C-I/C-I′/C-IV/C-II gene cluster. One of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54669c6cca2e2e4b22a0f2882924046
https://pubmed.ncbi.nlm.nih.gov/10893248
https://pubmed.ncbi.nlm.nih.gov/10893248