Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sharon F. Cruse"'
Autor:
Mark A. Scheideler, Sharon F. Cruse, Inger Søtofte, Annemarie Varming, Debasis Ghosh, Li Liang, Cheryl Klein-Stevens, A. Michael Crider, Xiaodong Song
Publikováno v:
European Journal of Medicinal Chemistry. 34:487-503
cis- and trans-2,3,3a,4,5,9b-Hexahydro-1H-benz[e]indoles were synthesized as conformationally rigid analogues of 3-phenylpyrrolidine and evaluated for dopamine (DA) D2S and D3 receptor binding affinity. The tricyclic benz[e]indole nucleus was constru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d125bc742294cc19f74bff20d081d77
https://doi.org/10.1016/s0223-5234(99)80098-1
https://doi.org/10.1016/s0223-5234(99)80098-1
Autor:
David S. Roane, Bin Ho, Prabha Venkatarangan, A. M. Crider, Ahmad A. Adloo, Sharon F. Cruse, Christine N. Hinko, James P. Stables, Peter H. Andersen
Publikováno v:
European Journal of Medicinal Chemistry. 33:23-31
A variety of 2-piperidinecarboxamides were synthesized and evaluated for anticonvulsant activity using the MES and sc PTZ tests in mice and rats. Neurotoxicity was determined by the rotorod test. Several N-(benzyl)-2-piperidinecarboxamides exhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81f8cadfd2d9e6d9a23b8eb322eea73b
https://doi.org/10.1016/s0223-5234(99)80072-5
https://doi.org/10.1016/s0223-5234(99)80072-5
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3307f9d209f20f928a187ff06e7426d
https://doi.org/10.1002/chin.199502093
https://doi.org/10.1002/chin.199502093
Autor:
Sharon F. Cruse, Ahmad A. Adloo, James P. Stables, Christine N. Hinko, David S. Roane, Peter H. Andersen, Prabha Venkatarangan, Bin Ho, A. M. Crider
Publikováno v:
ChemInform. 29
A variety of 2-piperidinecarboxamides were synthesized and evaluated for anticonvulsant activity using the MES and sc PTZ tests in mice and rats. Neurotoxicity was determined by the rotorod test. Several N-(benzyl)-2-piperidinecarboxamides exhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef7958269e7b452c4f8584fd63787271
https://doi.org/10.1002/chin.199827162
https://doi.org/10.1002/chin.199827162
Autor:
Inger Soetofte, Sharon F. Cruse, Xiaodong Song, Annemarie Varming, Debasis Ghosh, Li Liang, Cheryl Klein-Stevens, Mark A. Scheideler, A. Michael Crider
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b42b02c3fb6b3b8773c24fd04e58862
https://doi.org/10.1002/chin.199948134
https://doi.org/10.1002/chin.199948134
Publikováno v:
European Journal of Medicinal Chemistry. 27:407-411
A variety of 3-phenylpyrrolidines were synthesized and evaluated for their dopamine binding affinity in rat striatal tissue in vitro using [3H] SCH 23390 and [3H] spiperone as the D1 and D2 selective radioligands, respectively. Maximal D1 and D2 rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af46bda10f6d43ca7aa2ce028547228
https://doi.org/10.1016/0223-5234(92)90155-t
https://doi.org/10.1016/0223-5234(92)90155-t
Autor:
Anders Fink-Jensen, Debasis Ghosh, A.Micheal Crider, Niels Korsgaard, Lars Naerum, Thomas S. Ludvigsen, Mark A. Scheideler, Sharon F. Cruse, Philip J. Larsen, Rolf Hohlweg, Jesper Skou Rasmussen, Joel Martin
Publikováno v:
European journal of pharmacology. 339(2-3)
The affinity, selectivity and agonistic properties of a constrained dopaminergic compound, the benz[e]indole cis-8-hydroxy-3-(n-propyl)1,2,3a.4,5,9b-hexahydro-1H-benz[e]indole (cis-8-OH-PBZI), for the dopamine D3 receptor were evaluated in competitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a419ca34116e6d86b495870b55eae0e8
https://pubmed.ncbi.nlm.nih.gov/9473144
https://pubmed.ncbi.nlm.nih.gov/9473144
Autor:
Cheryl L. Klein, Sharon F. Cruse, Ronald M. Dick, A. Michael Crider, Peter H. Andersen, Jennifer Lear
Publikováno v:
Journal of pharmaceutical sciences. 82(3)
cis-1,2,3a,4,5,9b-Hexahydro-3H-benz[e]indoles were synthesized and evaluated for in vitro dopamine D1 and D2 receptor binding affinity. The target compounds 21-25 were readily prepared by reduction of the air-sensitive tricyclic enamines 10-14. Reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2219678855ac918affbebfc8d483942f
https://pubmed.ncbi.nlm.nih.gov/8095545
https://pubmed.ncbi.nlm.nih.gov/8095545
Publikováno v:
Bulletin of environmental contamination and toxicology. 36(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6650c439154950152ef724f744f6c191
https://pubmed.ncbi.nlm.nih.gov/2423161
https://pubmed.ncbi.nlm.nih.gov/2423161