Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sharon E. Pursglove"'
Autor:
Maria Sunnerhagen, Pär Säfsten, Sharon E. Pursglove, Ahmad Moshref, Kaisong Zhou, Malin Fladvad
Publikováno v:
Journal of Molecular Biology. 346:175-189
The proto-oncogene c-myc governs the expression of a number of genes targeting cell growth and apoptosis, and its expression levels are distorted in many cancer forms. The current investigation presents an analysis by proteolysis, circular dichroism,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c77f761f3b31da32680455e5b9d864
https://doi.org/10.1016/j.jmb.2004.11.029
https://doi.org/10.1016/j.jmb.2004.11.029
Autor:
Sharon E. Pursglove, Jannette Carey, Ahmad Moshref, Marie Henriksson, Massimo Bellanda, Malin Fladvad, Maria Sunnerhagen
Publikováno v:
Biochemical and Biophysical Research Communications. 323:750-759
The Max protein is the central dimerization partner in the Myc-Max-Mad network of transcriptional regulators, and a founding structural member of the family of basic-helix-loop-helix (bHLH)-leucine zipper (Zip) proteins. Biologically important region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b30b28e5f66578ce76d6207190a839
https://doi.org/10.1016/j.bbrc.2004.08.166
https://doi.org/10.1016/j.bbrc.2004.08.166
Autor:
Anna Bergman, Lars Lannfelt, Mark R. Farmery, Johan Lundkvist, Emil M. Hansson, Jan Näslund, Sharon E. Pursglove, Urban Lendahl
Publikováno v:
Journal of Biological Chemistry. 279:16744-16753
The gamma-secretase complex catalyzes intramembrane proteolysis of a number of transmembrane proteins, including amyloid precursor protein, Notch, ErbB4, and E-cadherin. gamma-Secretase is known to contain four major protein constituents: presenilin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94635bbee84cf822f44ca80f6e3beddf
https://doi.org/10.1074/jbc.m313999200
https://doi.org/10.1074/jbc.m313999200
Publikováno v:
FEBS Letters. 524:159-162
A cell-free protein expression system was established that provides protein samples of adequate concentration and purity for direct NMR analysis. The Escherichia coli peptidyl–prolyl cis–trans isomerase PpiB was expressed in this system with dual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98f0081d041381c3d059b39bb4e0afb
https://doi.org/10.1016/s0014-5793(02)03048-x
https://doi.org/10.1016/s0014-5793(02)03048-x
Autor:
Jacqueline A. Wilce, Jason W. Schmidberger, Corrine Joy Porter, Sharon E. Pursglove, Stephanie C. Pero, Jacaqueline M Matthews, Peter J. Leedman, Matthew C.J. Wilce, David N. Krag, Joel P. Mackay
Publikováno v:
BMC Structural Biology
BMC Structural Biology, Vol 7, Iss 1, p 58 (2007)
BMC Structural Biology, Vol 7, Iss 1, p 58 (2007)
Background Human g rowth factor r eceptor b ound protein 7 (Grb7) is an adapter protein that mediates the coupling of tyrosine kinases with their downstream signaling pathways. Grb7 is frequently overexpressed in invasive and metastatic human cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a938ed281094ecbe53a1677653f2350
https://pubmed.ncbi.nlm.nih.gov/17894853
https://pubmed.ncbi.nlm.nih.gov/17894853
Autor:
Maria Ankarcrona, Richard F. Cowburn, Camilla A. Hansson, Sharon E. Pursglove, Johan Thyberg, Akira Ito, Camilla Nilsberth, Mark R. Farmery, Susanne Frykman, Bengt Winblad, Lars O. Tjernberg
Publikováno v:
The Journal of biological chemistry. 279(49)
Mitochondria are central in the regulation of cell death. Apart from providing the cell with ATP, mitochondria also harbor several death factors that are released upon apoptotic stimuli. Alterations in mitochondrial functions, increased oxidative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d61b008a90b6a113d23b4ebe9bfdd1
https://pubmed.ncbi.nlm.nih.gov/15456764
https://pubmed.ncbi.nlm.nih.gov/15456764
Autor:
Lars O. Tjernberg, Anna Bergman, Sharon E. Pursglove, Mark R. Farmery, Bengt Winblad, Jan Näslund
Publikováno v:
The Journal of biological chemistry. 278(27)
One characteristic feature of Alzheimer's disease is the deposition of amyloid beta-peptide (Abeta) as amyloid plaques within specific regions of the human brain. Abeta is derived from the amyloid beta-peptide precursor protein (beta-APP) by the intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7840d16601c134301652f332bc87bc5
https://pubmed.ncbi.nlm.nih.gov/12697771
https://pubmed.ncbi.nlm.nih.gov/12697771
Publikováno v:
The Journal of biological chemistry. 277(1)
Tec is the prototypic member of a family of intracellular tyrosine kinases that includes Txk, Bmx, Itk, and Btk. Tec family kinases share similarities in domain structure with Src family kinases, but one of the features that differentiates them is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b764f28c115d0ccfecd61e8174d670af
https://pubmed.ncbi.nlm.nih.gov/11684687
https://pubmed.ncbi.nlm.nih.gov/11684687
Publikováno v:
Journal of Biomolecular NMR. 12:461-462
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::def50db165a3da5ed487fbf93e474619
https://doi.org/10.1023/a:1008307417981
https://doi.org/10.1023/a:1008307417981
Publikováno v:
Seibutsu Butsuri. 42:S149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff69ed3572705b00f9853894d13921db
https://doi.org/10.2142/biophys.42.s149_1
https://doi.org/10.2142/biophys.42.s149_1