Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sharon E. Groover"'
Publikováno v:
Journal of Chemical Education. 98:3011-3018
Traditional undergraduate biochemical laboratory curricula are confronted with challenges in improving student-learning outcomes while incorporating exciting and thought-provoking research-based laboratories due to limitations with time, increased st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb1227de946707eb12a69d7b5edd61d0
https://doi.org/10.1021/acs.jchemed.0c01473
https://doi.org/10.1021/acs.jchemed.0c01473
Autor:
Caleb K. Fan, Justin Legleiter, Sharon E. Groover, Maryssa Beasley, Katelyn Taylor, Adewale Adegbuyiro, Breanna L. Hodges, Chathuranga Siriwardhana, Alyssa R. Stonebraker
Publikováno v:
Colloids Surf B Biointerfaces
Huntington’s disease (HD) is a fatal neurodegenerative disease caused by an extended polyglutamine (polyQ) domain within the first exon of the huntingtin protein (htt). PolyQ expansion directly invokes the formation of a heterogenous mixture of tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7502d71cd85bf5c0322a2b25b82721d
https://europepmc.org/articles/PMC8429182/
https://europepmc.org/articles/PMC8429182/
Phosphomimetic Mutations Impact Huntingtin Aggregation in the Presence of a Variety of Lipid Systems
Publikováno v:
Biochemistry. 59(49)
Huntington's disease (HD) is a neurodegenerative disorder caused by the abnormal expansion of a polyglutamine (polyQ) tract in the first exon of the htt protein (htt). PolyQ expansion triggers the aggregation of htt into a variety of structures, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745b926803a6dd8edd764d077b3d3486
https://pubmed.ncbi.nlm.nih.gov/33256402
https://pubmed.ncbi.nlm.nih.gov/33256402
Publikováno v:
Biochim Biophys Acta Biomembr
Huntington's Disease is a fatal neurodegenerative disorder caused by expansion of a glutamine repeat region (polyQ) beyond a critical threshold within exon1 of the huntingtin protein (htt). As a consequence of polyQ expansion, htt associates into a v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71dfa28dc107a98aa92cce91d3801445
https://pubmed.ncbi.nlm.nih.gov/33130095
https://pubmed.ncbi.nlm.nih.gov/33130095
Autor:
Faezeh Sedighi, Barry J. Liang, Sharon E. Groover, Maryssa Beasley, Garima Agarwal, Alyssa R. Stonebraker, Iraj Hasan, Justin Legleiter, Kathryn L Kapp
Publikováno v:
Biochemistry
Several diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease (HD), are associated with specific proteins aggregating and depositing within tissues and/or cellular compartments. The aggregation of these proteins is ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf6742dee931f938ad4853f47bad9a4
https://pubmed.ncbi.nlm.nih.gov/31608620
https://pubmed.ncbi.nlm.nih.gov/31608620
Autor:
Blake Mertz, Stephen J. Valentine, Nicolas C. Frazee, Justin Legleiter, Maryssa Beasley, Sharon E. Groover
Publikováno v:
Biophysical Journal. 118:59a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6776d5cebc9f6ccc0b9cbce76f9a5821
https://doi.org/10.1016/j.bpj.2019.11.502
https://doi.org/10.1016/j.bpj.2019.11.502
Autor:
Sharon E. Groover, Adewale Adegbuyiro, Justin Legleiter, Faezeh Sedighi, Albert W. Pilkington
Several hereditary neurological and neuromuscular diseases are caused by an abnormal expansion of trinucleotide repeats. To date, there have been ten of these trinucleotide repeat disorders associated with an expansion of the codon CAG encoding gluta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588414cce1c8284bfbbf1e5a3d3d624d
https://europepmc.org/articles/PMC5727916/
https://europepmc.org/articles/PMC5727916/
Publikováno v:
Biophysical Journal. 116:369a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c14a91150300a2197b9a08868824fd8
https://doi.org/10.1016/j.bpj.2018.11.2009
https://doi.org/10.1016/j.bpj.2018.11.2009
Publikováno v:
Biophysical Journal. 116:455a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::703748dbf3811323f141e2119de5b920
https://doi.org/10.1016/j.bpj.2018.11.2457
https://doi.org/10.1016/j.bpj.2018.11.2457