Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Sharon E, Murphy"'
Autor:
Dorothy K. Hatsukami, Joni A. Jensen, Dana Mowls Carroll, Xianghua Luo, Lori G. Strayer, Qing Cao, Stephen S. Hecht, Sharon E. Murphy, Steven G. Carmella, Rachel L. Denlinger-Apte, Suzanne Colby, Andrew A. Strasser, F. Joseph McClernon, Jennifer Tidey, Neal L. Benowitz, Eric C. Donny
Publikováno v:
The Lancet Regional Health. Americas, Vol 35, Iss , Pp 100796- (2024)
Summary: Background: Reducing cigarette addictiveness has the potential to avert millions of yearly tobacco-related deaths worldwide. Substantially reducing nicotine in cigarettes decreases cigarette consumption, but no large clinical trial has deter
Externí odkaz:
https://doaj.org/article/6a4dde46962446d29ed25eb6a4cf33b4
Autor:
James W. Baurley, Andrew W. Bergen, Carolyn M. Ervin, Sung-shim Lani Park, Sharon E. Murphy, Christopher S. McMahan
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background There is a need to match characteristics of tobacco users with cessation treatments and risks of tobacco attributable diseases such as lung cancer. The rate in which the body metabolizes nicotine has proven an important predictor
Externí odkaz:
https://doaj.org/article/cec72d3c51bf441289d989f835ab5d26
Autor:
Margaret R Karagas, Janet L Peacock, Sharon E Murphy, Thomas J Palys, Yuliya Halchenko, Vicki Sayarath, Cindy A Takigawa, Lisa A Peterson, Emily R Baker
Publikováno v:
BMJ Open, Vol 12, Iss 2 (2022)
Objectives Accurate assessment of tobacco smoke exposure is key to evaluate its effects. We sought to validate and establish cut-offs for self-reported smoking and secondhand smoke (SHS) exposure during pregnancy using urinary cotinine and 4-(methyln
Externí odkaz:
https://doaj.org/article/b8b648c3c6c94b27a78f918b3ecb1268
Autor:
Linda B. von Weymarn, Xiaotong Lu, Nicole M. Thomson, Loic LeMarchand, Sungshim L. Park, Sharon E. Murphy
Publikováno v:
Chem Res Toxicol
Smoking intensity varies across smokers and is influenced by individual variability in the metabolism of nicotine, the major addictive agent in tobacco. Therefore, lung cancer risk, which varies by racial ethnic group is influenced by the primary cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e900c73b74bcfb72af3742a167c07a6b
https://doi.org/10.1021/acs.chemrestox.2c00413
https://doi.org/10.1021/acs.chemrestox.2c00413
Autor:
Sungshim L. Park, Yesha M. Patel, Lenora W. M. Loo, Daniel J. Mullen, Ite A. Offringa, Alika Maunakea, Daniel O. Stram, Kimberly Siegmund, Sharon E. Murphy, Maarit Tiirikainen, Loïc Le Marchand
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Lung cancer is the leading cause of cancer-related death. While cigarette smoking is the primary cause of this malignancy, risk differs across racial/ethnic groups. For the same number of cigarettes smoked, Native Hawaiians compar
Externí odkaz:
https://doaj.org/article/67c88d458b6545b0886b02eff2c43a85
Autor:
Stephen S. Hecht, Dorothy Hatsukami, Mimi C. Yu, Heather H. Nelson, Mindy S. Kurzer, Chap Le, Pramod Upadhyaya, Jennifer Adams-Haduch, Lori Strayer, Joni Jensen, Sharon Allen, Renwei Wang, Sharon E. Murphy, Irina Stepanov, Jian-Min Yuan
2-Phenethyl isothiocyanate (PEITC), a natural product found as a conjugate in watercress and other cruciferous vegetables, is an inhibitor of the metabolic activation and lung carcinogenicity of the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8477cdbacdf5ee39f778650a5a69684
https://doi.org/10.1158/1940-6207.c.6547427.v1
https://doi.org/10.1158/1940-6207.c.6547427.v1
Nicotine replacement therapy is often used to maintain smoking cessation. However, concerns exist about the safety of long-term nicotine replacement therapy use in ex-smokers and its concurrent use in smokers. In this study, we determined the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d077e894dee27aac70d563d3143563fe
https://doi.org/10.1158/1940-6207.c.6544277
https://doi.org/10.1158/1940-6207.c.6544277
Autor:
Stephen S. Hecht, Dorothy Hatsukami, Heather H. Nelson, Steven G. Carmella, Renwei Wang, Irina Stepanov, Sharon E. Murphy, Jian-Min Yuan
Cigarette smoke contains relatively large quantities of volatile organic toxicants or carcinogens such as benzene, acrolein, and crotonaldehyde. Among their detoxification products are mercapturic acids formed from glutathione conjugation, catalyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::727f06e1260b789eeed906df3bc0ec9f
https://doi.org/10.1158/1940-6207.c.6547301.v1
https://doi.org/10.1158/1940-6207.c.6547301.v1
Autor:
Stephen S. Hecht, Dorothy Hatsukami, Mimi C. Yu, Heather H. Nelson, Mindy S. Kurzer, Chap Le, Pramod Upadhyaya, Jennifer Adams-Haduch, Lori Strayer, Joni Jensen, Sharon Allen, Renwei Wang, Sharon E. Murphy, Irina Stepanov, Jian-Min Yuan
Table S1. Number of [pyridine-D4]NNK cigarettes smoked per day by study participants by treatment sequence groups and treatment period, The PEITC Intervention Study 2008-2013 Table S2. Spearman correlation coefficients between number of cigarettes pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec0f812350946da1d06a3ea6ccd361c
https://doi.org/10.1158/1940-6207.22534253
https://doi.org/10.1158/1940-6207.22534253
Perspectives on This Article from Chronic Nicotine Consumption Does Not Influence 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone–Induced Lung Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc7fcc7976dc15558627c4f64a734c8
https://doi.org/10.1158/1940-6207.22524494.v1
https://doi.org/10.1158/1940-6207.22524494.v1