Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sharon Colayco"'
Autor:
Yongmei Feng, Stefan Grotegut, Predrag Jovanovic, Valentina Gandin, Steven H. Olson, Rabi Murad, Anne Beall, Sharon Colayco, Paul De-Jesus, Sumit Chanda, Brian P. English, Robert H. Singer, Michael Jackson, Ivan Topisirovic, Ze’ev A. Ronai
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The translation initiation complex 4F (eIF4F) is a rate-limiting factor in protein synthesis. Alterations in eIF4F activity are linked to several diseases, including cancer and infectious diseases. To this end, coronaviruses require eIF4F complex act
Externí odkaz:
https://doaj.org/article/3f5893fb1bab4b94b39dab0daec38624
Autor:
Xochella Chan, Eduard Sergienko, David A Critton, Ekaterina V. Bobkova, Nicholas D. P. Cosford, Li Yang, Rebecca Page, Paul J. Lombroso, Brock Brown, Shyama Sidique, Justin Rascon, Stefan Vasile, Ying Su, Thomas D.Y. Chung, Russell Dahl, Tomas Mustelin, Hongbin Yuan, Sharon Colayco, Wallace Liu, Lutz Tautz, Jian Xu
Publikováno v:
ACS Chemical Biology. 7:367-377
The hematopoietic protein tyrosine phosphatase (HePTP) is implicated in the development of blood cancers through its ability to negatively regulate the mitogen-activated protein kinases (MAPKs) ERK1/2 and p38. Small-molecule modulators of HePTP activ
Autor:
Ekaterina V. Bobkova, Wallace Liu, Lutz Tautz, Xochella Chan, David A Critton, Stefan Vasile, Rebecca Page, Tomas Mustelin, Sharon Colayco, Thomas D.Y. Chung, Carlton Gasior, Ying Su, Justin Rascon, Russell Dahl, Eduard Sergienko
Publikováno v:
ACS Medicinal Chemistry Letters. 2:113-118
Protein tyrosine phosphatases (PTPs) have only recently become the focus of attention in the search for novel drug targets despite the fact that they play vital roles in numerous cellular processes and are implicated in many human diseases. The hemat