Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Sharon Byers"'
Autor:
Matthew Prideaux, Christian S. Wright, Megan L. Noonan, Xin Yi, Erica L. Clinkenbeard, Elsa Mevel, Jonathan A. Wheeler, Sharon Byers, Asiri R. Wijenayaka, Stan Gronthos, Uma Sankar, Kenneth E. White, Gerald J. Atkins, William R. Thompson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Mesenchymal progenitors differentiate into several tissues including bone, cartilage, and adipose. Targeting these cells in vivo is challenging, making mesenchymal progenitor cell lines valuable tools to study tissue development. Mesenchymal
Externí odkaz:
https://doaj.org/article/f7398838cd214c8aba8d0dac83a09d11
Autor:
Rebecca J. Lehmann, Lachlan A. Jolly, Brett V. Johnson, Megan S. Lord, Ha Na Kim, Jennifer T. Saville, Maria Fuller, Sharon Byers, Ainslie L.K. Derrick-Roberts
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 29, Iss , Pp 100811- (2021)
Mucopolysaccharidosis type IIIA (MPS IIIA) is characterised by a progressive neurological decline leading to early death. It is caused by bi-allelic loss-of-function mutations in SGSH encoding sulphamidase, a lysosomal enzyme required for heparan sul
Externí odkaz:
https://doaj.org/article/af43741fe8bf40afb6575ab48eb56474
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 25, Iss , Pp 100668- (2020)
Bone elongation is driven by chondrocyte proliferation and hypertrophy in the growth plate. Both processes are modulated by multiple signaling pathways including the Indian Hedgehog (IHH) signaling pathway. Mucopolysaccharidoses (MPS) are a group of
Externí odkaz:
https://doaj.org/article/39b91f4575ef480ba7c8e5b2231827fc
Publikováno v:
Diseases, Vol 5, Iss 1, p 5 (2017)
Mucopolysaccharidosis type I (MPS I) is the most common form of the MPS group of genetic diseases. MPS I results from a deficiency in the lysosomal enzyme α-l-iduronidase, leading to accumulation of undegraded heparan and dermatan sulphate glycosami
Externí odkaz:
https://doaj.org/article/0b98d3909f0341459ba9eda401fb0aea
Autor:
Wan Chin Liaw, Janice M. Fletcher, Peter Sharp, Matilda R. Jackson, Xiaodan Ding, Chun Ong, Xenia Kaidonis, Enzo Ranieri, Sharon Byers, Ainslie L.K. Derrick-Roberts
Publikováno v:
Molecular Genetics and Metabolism. 131:197-205
The cause of neurodegeneration in MPS mouse models is the focus of much debate and what the underlying cause of disease pathology in MPS mice is. The timing of development of pathology and when this can be reversed or impacted is the key to developin
Autor:
Jennifer T. Saville, Ainslie L. K. Derrick-Roberts, Brett V. Johnson, Megan S. Lord, Maria Fuller, Ha Na Kim, Lachlan A. Jolly, Rebecca J. Lehmann, Sharon Byers
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 29, Iss, Pp 100811-(2021)
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports
Mucopolysaccharidosis type IIIA (MPS IIIA) is characterised by a progressive neurological decline leading to early death. It is caused by bi-allelic loss-of-function mutations in SGSH encoding sulphamidase, a lysosomal enzyme required for heparan sul
Autor:
Xin Yi, Matthew Prideaux, Erica L. Clinkenbeard, Asiri R. Wijenayaka, Sharon Byers, Uma Sankar, Gerald J. Atkins, Kenneth E. White, Jonathan A. Wheeler, Megan L. Noonan, William R. Thompson, Stan Gronthos, Christian S. Wright, Elsa Mevel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Mesenchymal progenitors differentiate into several tissues including bone, cartilage, and adipose. Targeting these cells in vivo is challenging, making mesenchymal progenitor cell lines valuable tools to study tissue development. Mesenchymal stem cel
Autor:
Xin Yi, William R. Thompson, Matthew Prideaux, Erica L. Clinkenbeard, Uma Sankar, Sharon Byers, Jonathan A. Wheeler, Christian S. Wright, Elsa Mevel, Kenneth E. White, Megan L. Noonan, Gerald J. Atkins
Differentiation of multi-potent mesenchymal progenitor cells give rise to several tissue types including bone, cartilage, and adipose. In addition to the complication arising from the numerous spatial, temporal, and hormonal factors that regulate lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242a99bcf843943c8a502e2fb8f2d509
https://doi.org/10.1101/2020.11.19.385138
https://doi.org/10.1101/2020.11.19.385138
Publikováno v:
Curr Osteoporos Rep
PURPOSE OF REVIEW: The mucopolysaccharidoses (MPS) are a group of inherited lysosomal storage disorders characterized by abnormal accumulation of glycosaminoglycans (GAGs) in cells and tissues. MPS patients frequently exhibit failures of endochondral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216c506d40fb8965a604056e21f165b8
https://europepmc.org/articles/PMC7736118/
https://europepmc.org/articles/PMC7736118/
Autor:
Ainslie Derrick-Roberts, Xenia Kaidonis, Matilda R. Jackson, Wan Chin Liaw, XiaoDan Ding, Chun Ong, Enzo Ranieri, Peter Sharp, Janice Fletcher, Sharon Byers
Publikováno v:
Molecular Genetics and Metabolism. 135:114