Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sharon Bloch"'
Autor:
W. Barry Edwards, Walter J. Akers, Yunpeng Ye, Philip P. Cheney, Sharon Bloch, Baogang Xu, Richard Laforest, Samuel Achilefu
Publikováno v:
Molecular Imaging, Vol 8 (2009)
Integrins, particularly the α v β 3 heterodimers, play important roles in tumor-induced angiogenesis and invasiveness. To image the expression pattern of the α v β 3 integrin in tumors through a multimodality imaging paradigm, we prepared a cycli
Externí odkaz:
https://doaj.org/article/b34da44a26ea4b85a54ef91a7c3cb795
Autor:
Avik Som, Samuel Achilefu, Kevin Guo, Sid Kurkure, Rebecca C. Gilson, Baogang Xu, Dolonchampa Maji, Shaw-Wei D. Tsen, Yang Liu, Suman B. Mondal, LeMoyne Habimana-Griffin, Walter J. Akers, Alexander Seidel, Christopher Egbulefu, Duanwen Shen, Sharon Bloch, Zohar Nussinov, Kexian Liang, Shunqiang Li, Gail Sudlow, Rui Tang
Publikováno v:
Nature Biomedical Engineering. 4:298-313
The heterogeneity and continuous genetic adaptation of tumours complicate their detection and treatment via the targeting of genetic mutations. However, hallmarks of cancer such as aberrant protein phosphorylation and calcium-mediated cell signalling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b115c306fa5c620c92be7127f409af78
https://doi.org/10.1038/s41551-020-0528-7
https://doi.org/10.1038/s41551-020-0528-7
Autor:
Jinda Fan, Pratim Biswas, Samuel Achilefu, Charles A. Odonkor, Kexian Liang, Sharon Bloch, Baogang Xu, W. B. Edwards, Soubir Basak, Rachel L. Mintz, Philip P. Cheney
Publikováno v:
Curr Anal Chem
Background: Gold nanoparticles (AuNPs) are commonly used in nanomedicine because of their unique spectral properties, chemical and biological stability, and ability to quench the fluorescence of organic dyes attached to their surfaces. However, the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bd064963b3caeaca62cb132ca86866
https://europepmc.org/articles/PMC8356907/
https://europepmc.org/articles/PMC8356907/
Autor:
Samuel Achilefu, Steven L. Brody, Mikhail Y. Berezin, Natalia G. Zhegalova, Sharon Bloch, Sean P. Gunsten, Walter J. Akers, J. Christopher Holley, William C. Eades, Haiying Zhou, Daniel Schweppe
Publikováno v:
Cytometry Part A. 87:419-427
In vivo optical imaging with near-infrared (NIR) probes is an established method of diagnostics in preclinical and clinical studies. However, the specificities of these probes are difficult to validate ex vivo due to the lack of NIR flow cytometry. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eecbb0c6a97ffb4e41a9414005faddc
https://doi.org/10.1002/cyto.a.22658
https://doi.org/10.1002/cyto.a.22658
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:5405-5409
A new near-infrared fluorescent compound containing two cyclic RGD motifs, cypate-[c(RGDfK)](2) (1), was synthesized based on a carbocyanine fluorophore bearing two carboxylic acid groups (cypate) for integrin α(v)β(3)-targeting. Compared with its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f910a042b604750463d763acd57879
https://doi.org/10.1016/j.bmcl.2012.07.044
https://doi.org/10.1016/j.bmcl.2012.07.044
Publikováno v:
Journal of Microscopy. 247:202-207
Although single-photon fluorescence lifetime imaging microscopy (FLIM) is widely used to image molecular processes using a wide range of excitation wavelengths, the captured emission of this technique is confined to the visible spectrum. Here, we exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2c150f54b00c0923850d81e28ab8d0e
https://doi.org/10.1111/j.1365-2818.2012.03634.x
https://doi.org/10.1111/j.1365-2818.2012.03634.x
Publikováno v:
Bioconjugate Chemistry. 16:1232-1239
Diagnosis of diseases by different imaging methods can provide complementary information about the functional status of diseased tissues or organs. To overcome the current difficulties in coregistering images from different imaging modalities with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ec2c64709e4ef543ab3c5f6c794a93
https://doi.org/10.1021/bc050136s
https://doi.org/10.1021/bc050136s
Autor:
Mary A. Markiewicz, Samuel Achilefu, Sharon Bloch, Britton Chance, Richard B. Dorshow, Kexian Liang, Yunpeng Ye, Tuoxiu Zhong
Publikováno v:
Proceedings of the National Academy of Sciences. 102:7976-7981
Integrins mediate many biological processes, including tumor-induced angiogenesis and metastasis. The arginine–glycine–aspartic acid (RGD) peptide sequence is a common recognition motif by integrins in many proteins and small peptides. While eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b60411ac87cc84a1448b1b4c38bb8d
https://doi.org/10.1073/pnas.0503500102
https://doi.org/10.1073/pnas.0503500102
Publikováno v:
Bioconjugate Chemistry. 16:51-61
Synergistic multivalent interactions can amplify desired chemical or biological molecular recognitions. We report a new class of multicarboxylate-containing carbocyanine dye constructs for use as optical scaffolds that not only serve as fluorescent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183f46781924aa1f9e449300b597af33
https://doi.org/10.1021/bc049790i
https://doi.org/10.1021/bc049790i