The Expression and Regulation of Adrenomedullin in the Human Endometrium: A Candidate for Endometrial Repair

Autor: Henry N. Jabbour, Sharon Battersby, Hilary O. D. Critchley, Jacqueline A. Maybin, Nikhil Hirani, Leonid L. Nikitenko

Publikováno v: Endocrinology
Maybin, J A, Battersby, S, Hirani, N, Nikitenko, L L, Critchley, H O D & Jabbour, H N 2011, ' The expression and regulation of adrenomedullin in the human endometrium : a candidate for endometrial repair ', Endocrinology, vol. 152, no. 7, pp. 2845-2856 . https://doi.org/10.1210/en.2010-1256

After menstruation, the endometrium has a remarkable capacity for repair, but the factors involved remain undefined. We hypothesize adrenomedullin (AM) plays a role in this process. Premenstrually progesterone levels decline, stimulating prostaglandi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7737c80f416e2aa6eefb614acdff723
http://europepmc.org/articles/PMC3192419

Serotonin transporter 5HTTLPR polymorphism and affective disorders: no evidence of association in a large European multicenter study

Autor: Alessandro Serretti, Julien Mendlewicz, Jurgen Del-Favero, Ronen Segman, Roberta Lilli, Markus M. Nöthen, Miro Jakovljević, Lilijana Oruc, Walter J. Muir, Marcella Rietschel, Sharon Battersby, Beny Lerer, Isabelle Massat, Douglas Blackwood, Daniel Souery, Christine Van Broeckhoven, Radka Kaneva, Christian Lorenzi, Vihra Milanova, Sladana Ivezic

Publikováno v: European journal of human genetics

The available data from preclinical and pharmacological studies on the role of the serotonin transporter (5-HTT) support the hypothesis that a dysfunction in brain serotonergic system activity contributes to the vulnerability to affective disorders (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98abe32fe91f9cbdb0cf4cc2c69bec2b
https://doi.org/10.1038/sj.ejhg.5201149

Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition

Autor: Sharon Battersby, Filiberto Maria Severi, Jane E. Norman, Romina Novembri, Michela Torricelli, Felice Petraglia, Chiara Voltolini

Publikováno v: Endocrinology. 156(2)

The purpose of the study was to investigate urocortin (Ucn)2 involvement in placental and myometrial inflammatory pathways associated with parturition by evaluating: 1) Ucn2 and its receptor, CRH-receptor type 2 (CRH-R2), expression in laboring/nonla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ab0b420134d9597e9e172e9a3630a5
https://pubmed.ncbi.nlm.nih.gov/25426872

Refined mapping of the human serotonin transporter (SLC6A4) gene within 17q11 adjacent to the CPD and NF1 genes

Autor: Elma Clark, Molly Weaver, Anthony J. Harmar, Karen Stephens, Sanbing Shen, Sharon Battersby

Publikováno v: European Journal of Human Genetics. 8:75-78

The SLC6A4 gene encodes the serotonin transporter, the target of an important class of antidepressant drugs (serotonin selective reuptake inhibitors). Polymorphisms in the SLC6A4 gene have been reported to be associated with susceptibility to depress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0273d8060ec8bb2362abe84b5ed0865e
https://doi.org/10.1038/sj.ejhg.5200400

Structure of a variable number tandem repeat of the serotonin transporter gene and association with affective disorder

Autor: D. H. R. Blackwood, Walter J. Muir, John P. Quinn, C A D Smith, George Fink, A J Harmar, Alan D. Ogilvie, G M Goodwin, Sharon Battersby

Publikováno v: Scopus-Elsevier

We have recently reported an association between a polymorphism of a variable number tandem repeat (VNTR) region of the serotonin transporter gene and susceptibility to major depressive disorder. We identified three alleles containing respectively 9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd19695d743ed6c46636cbd6e7089d4
https://doi.org/10.1097/00041444-199624000-00001