Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sharon B. Williams"'
Autor:
Carol L. Delaney, Suzanne Moreland, Zhengxiang Gu, Tamara Dejneka, Ellen Sieber-McMaster, Thomas L. Waldron, Michael A. Poss, J.Eileen Bird, Edward W. Petrillo, Ervin R. Spitzmiller, Denis E. Ryono, Sharon B. Williams, T. R. Schaeffer, S.Anders Hedberg, Kenneth E.J. Dickinson, Joyce A. Reid
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:145-150
The syntheses and pharmacological activity of a series of 1,4-substituted indoles which function as nonpeptidic antagonists of the angiotensin II (AII) receptor are described. Compounds in this series are orally active and demonstrate long lasting an
Autor:
Robert V. Moquin, Suzanne Moreland, Carol L. Delaney, Sharon B. Williams, S. Skwish, S.Anders Hedberg, Kenneth E.J. Dickinson, Harold N. Weller, Robert Cohen, Arthur V. Miller
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:1115-1120
N-Biphenylmethyl benzothiadiazine dioxides were prepared as potential angiotensin-II receptor antagonists. Stability of the compounds is dependent upon the nature of the substituent at position 3 of the benzothiadiazine ring, while potency is depende