Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sharon Avkin"'
Autor:
Ofer Levy, Assaf Marcus, Michal Golan Mashiach, Sharon Avkin Nachum, Jitka Sagiv, Reut Nave, Dor Shimon, Shiran Barber Zuker, Chen Harush, Megi Cemel David, Maayan Shamsian, Gil Friedman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b7eee47bb7684e1492f4557793e43af5
Autor:
Hagar Kalinski, Dina Polyak, Lorenzo Albertazzi, Anna Scomparin, Sharon Avkin-Nachum, Ronit Satchi-Fainaro, Natàlia Feiner Gracia, Paula Ofek, Shay Eliyahu, Adva Krivitsky, Galia Tiram
RNAi therapeutics carried a great promise to the area of personalized medicine: the ability to target "undruggable" oncogenic pathways. Nevertheless, their efficient tumor targeting via systemic administration had not been resolved yet. Amphiphilic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8b742c3da2ece9ad63953bfffc62c7
http://hdl.handle.net/2318/1691446
http://hdl.handle.net/2318/1691446
Autor:
Asaf Ori, Anna Scomparin, Sharon Avkin-Nachum, Ronit Satchi-Fainaro, Dina Polyak, Shay Eliyahu, Vadim Krivitsky, Adva Krivitsky
Publikováno v:
Biomacromolecules. 17(9)
It has been two decades since cationic polymers were introduced to the world of oligonucleotides delivery. However, the optimal physicochemical properties to make them a successful delivery vehicle are yet unknown. An ideal system became particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0773309caa07c1ff1b9241bca291570e
https://pubmed.ncbi.nlm.nih.gov/27377188
https://pubmed.ncbi.nlm.nih.gov/27377188
Autor:
Dina Polyak, Hagar Kalinski, Shay Eliyahu, Adva Krivitsky, Anna Scomparin, Sharon Avkin-Nachum, Ronit Satchi-Fainaro
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 257
Small interfering RNA (siRNA) can silence the expression of a targeted gene in a process known as RNA interference (RNAi). As a consequence, RNAi has immense potential as a novel therapeutic approach in cancer targeted therapy. However, successful ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8875f6d0f170ca2ee58b3a37819f0eca
https://pubmed.ncbi.nlm.nih.gov/27356019
https://pubmed.ncbi.nlm.nih.gov/27356019
Autor:
Sharon Avkin, Nicholas E. Geacintov, Stephen G. Chaney, Leanne Toube, Zvi Livneh, Moshe Oren, Ziv Sevilya
Publikováno v:
Molecular Cell. 22(3):407-413
Regulation of mutation rates is critical for maintaining genome stability and controlling cancer risk. A special challenge to this regulation is the presence of multiple mutagenic DNA polymerases in mammals. These polymerases function in translesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e85d67395732ae6f18f153b2bc55356
Autor:
Nicholas E. Geacintov, Zvi Livneh, Susana Velasco-Miguel, Sharon Avkin, Moshe Goldsmith, Errol C. Friedberg
Publikováno v:
Journal of Biological Chemistry. 279:53298-53305
Replication across unrepaired DNA lesions in mammalian cells is effected primarily by specialized, low fidelity DNA polymerases. We studied translesion DNA synthesis (TLS) across a benzo[a]pyrene-guanine (BP-G) adduct, a major mutagenic DNA lesion ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e56f6f18c5fb2abb4f50f05a65172add
https://doi.org/10.1074/jbc.m409155200
https://doi.org/10.1074/jbc.m409155200
Publikováno v:
Proceedings of the National Academy of Sciences. 99:3764-3769
Mutations in oncogenes and tumor suppressor genes are critical in the development of cancer. A major pathway for the formation of mutations is the replication of unrepaired DNA lesions. To better understand the mechanism of translesion replication (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc585e715ff4852ee15572b4ffd8fc0
https://doi.org/10.1073/pnas.062038699
https://doi.org/10.1073/pnas.062038699
Autor:
Isabel Muñoz-Barroso, Robert Blumenthal, Yechiel Shai, Yossef Kliger, Sergio G. Peisajovich, Stephen A. Gallo, Sharon Avkin
Publikováno v:
Journal of Biological Chemistry. 276:1391-1397
DP178, a synthetic peptide corresponding to a segment of the transmembrane envelope glycoprotein (gp41) of human immunodeficiency virus, type 1 (HIV-1), is a potent inhibitor of viral infection and virus-mediated cell-cell fusion. Nevertheless, DP178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7944bd8756058c13245a5f3c9d5c8e2
https://doi.org/10.1074/jbc.m004113200
https://doi.org/10.1074/jbc.m004113200
Autor:
Sharon, Avkin, Moshe, Goldsmith, Susana, Velasco-Miguel, Nicholas, Geacintov, Errol C, Friedberg, Zvi, Livneh
Publikováno v:
The Journal of biological chemistry. 279(51)
Replication across unrepaired DNA lesions in mammalian cells is effected primarily by specialized, low fidelity DNA polymerases. We studied translesion DNA synthesis (TLS) across a benzo[a]pyrene-guanine (BP-G) adduct, a major mutagenic DNA lesion ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ee008d6bd74c8156b0f213dbf305624
https://pubmed.ncbi.nlm.nih.gov/15475561
https://pubmed.ncbi.nlm.nih.gov/15475561
Autor:
Zvi Livneh, Sharon Avkin
Publikováno v:
Mutation research. 510(1-2)
The oxidation product of guanine, 8-oxoguanine, is a major lesion formed in DNA by intracellular metabolism, ionizing radiation, and tobacco smoke. Using a recently developed method for the quantitative analysis of translesion replication, we have st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e5fe4ff0d314bd1ab8887feede574d
https://pubmed.ncbi.nlm.nih.gov/12459445
https://pubmed.ncbi.nlm.nih.gov/12459445