Zobrazeno 1 - 10 of 46 pro vyhledávání: '"Sharon A. Jubrias"'
1
Skeletal Muscle Mitochondrial Function and Fatigability in Older Adults
Autor: Sharon A. Jubrias, Kevin E. Conley, Anne B. Newman, Robert M. Boudreau, Dawn C. Mackey, Paul M. Coen, Nancy W. Glynn, Bret H. Goodpaster, Adam J. Santanasto, Eleanor M. Simonsick, Elsa S. Strotmeyer, Francesca Amati
Publikováno v: The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 70, no. 11, pp. 1379-1385
Fatigability increases while the capacity for mitochondrial energy production tends to decrease significantly with age. Thus, diminished mitochondrial function may contribute to higher levels of fatigability in older adults. The relationship between
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f4251ad47560e88b02357faaad67dd
https://doi.org/10.1093/gerona/glu134
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2
Elevated energy coupling and aerobic capacity improves exercise performance in endurance-trained elderly subjects
Autor: Sharon A. Jubrias, M. Elaine Cress, Peter C. Esselman, Kevin E. Conley
Publikováno v: Experimental Physiology. 98:899-907
Increased maximal oxygen uptake (V(O(2)max)), mitochondrial capacity and energy coupling efficiency are reported after endurance training (ET) in adult subjects. Here we test whether leg exercise performance (power output of the legs, P(max), at V(O(
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f60cb7b6efb68f52dbc3d39e5fa34352
https://doi.org/10.1113/expphysiol.2012.069633
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3
CKD and Muscle Mitochondrial Energetics
Autor: Kevin E. Conley, Jonathan Himmelfarb, Bryan Kestenbaum, Ernest Ayers, Baback Roshanravan, Laura Curtin, Jorge L. Gamboa, Ian H. de Boer, Sharon A. Jubrias
Chronic kidney disease (CKD) leads to the retention of uremic solutes that disrupt skeletal muscle function1 leading to reduced physical performance and mobility limitation2. Disruption of muscle mitochondrial energetics in CKD may precede the onset
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57399a02a37324d3de56ff70d5db313b
https://europepmc.org/articles/PMC5063821/
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4
Mitochondrial NAD(P)H In vivo: Identifying Natural Indicators of Oxidative Phosphorylation in the 31P Magnetic Resonance Spectrum
Autor: Eric G. Shankland, Amir S. Ali, Kevin E. Conley, Brandon Flores, Sharon A. Jubrias
Publikováno v: Frontiers in Physiology, Vol 7 (2016)
Frontiers in Physiology
Natural indicators provide intrinsic probes of metabolism, biogenesis and oxidative protection. Nicotinamide adenine dinucleotide metabolites (NAD(P)) are one class of indicators that have roles as co-factors in oxidative phosphorylation, glycolysis,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98328db507ab1a8254a077a744627497
https://doi.org/10.3389/fphys.2016.00045
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5
Pioglitazone-induced improvements in insulin sensitivity occur without concomitant changes in muscle mitochondrial function
Autor: Sharon A. Jubrias, Lauren M. Sparks, Cecilia Gamboa, Steven R. Smith, Olga Sereda, Sudip Bajpeyi, Kori Murray, Bradley R. Newcomer, Kevin E. Conley, Magdalena Pasarica
Publikováno v: Metabolism: clinical and experimental. 69
Aims Pioglitazone (Pio) is known to improve insulin sensitivity in skeletal muscle. However, the role of Pio in skeletal muscle lipid metabolism and skeletal muscle oxidative capacity is not clear. The aim of this study was to determine the effects o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7082fdd6a422ab0bc892b953a808507e
https://pubmed.ncbi.nlm.nih.gov/28285649
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6
Skeletal Muscle Mitochondrial Capacity and Insulin Resistance in Type 2 Diabetes
Autor: Sharon A. Jubrias, Olga Sereda, Zhengyu Zhang, Steven R. Smith, Lise Kjems, Cedric Moro, David H. Burk, Alok Gupta, Sudip Bajpeyi, Kevin E. Conley, Magdalena Pasarica
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 96:1160-1168
The objective of this study was to determine the role of maximum mitochondrial capacity on the variation in insulin sensitivity within a population of patients with type 2 diabetes mellitus (T2DM).Fifty-eight participants enrolled in a cross-sectiona
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c90422519e6efb574d88cd87b2793fe
https://doi.org/10.1210/jc.2010-1621
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8
Second Annual Huntington Disease Clinical Research Symposium
Autor: Mark Guttman, David Eidelberg, D. J. Marcinek, S. Lessig, M. Delatycki, V. Collins, Lewis Maltby, B. Bartlett, Terrence Sills, R. C. Block, Anthony L. Vaccarino, D.R. Langbehn, J. H. Cha, Aileen Shinaman, A. Churchyard, Hans J. Johnson, P. Phan, Christopher A. Ross, O. Yastrubetskaya, Peter Como, E. Chiu, S. K. Kostyk, FuRST-pHD, C. A. Beck, C. Cimino, P. Chua, E. H. Aylward, D. A. Kegelmeyer, Charles Sabine, L. Tippett, K. Trembath, Henry L. Paulson, K. Rowe, Todd L. Richards, Kurt E. Weaver, Kenneth E. Evans, Kimberly A. Quaid, A. Goh, G. M. Peavy, A. D. Kloos, Chris C. Tang, V. Magnotta, O. Liang, William Adams, Richard Roxburgh, Dennis Velakoulis, Jess G. Fiedorowicz, P. Gilbert, Jan Bausch, J. C. Stout, Elizabeth Aylward, B. Stell, M. Pugliese, M. Jacobson, L. Veatch Goodman, Kevin Duff, J. Annis, K. L. Poston, L. J. Beglinger, Beth Borowsky, S. Christensen, Jody Goldstein, J. Sanchez-Ramos, E. Shankland, Guerry M. Peavy, M. McCall, A. Callazo, Elise Kayson, Jane S. Paulsen, E. Oster, F. Judd, D. van Kammen, E. R. Dorsey, A. Leserman, L. Ling, A. Feigin, Karen E. Anderson, London C Butterfield, Yilong Ma, E. Pirogovsky, Jody Corey-Bloom, Sharon A. Jubrias, Kevin E. Conley, Peg Nopoulos, David Oakes, V. Hogg, J. F. O’Rourke, Predict-Hd Investigators, J Giuliano, Ronald Pierson, Vijay Dhawan, A. Juhl, L. Oelke, C. Wang, D. Lovecky, C. Amara, B. Tress, Aileen K Ho, I. Shoulson, Z. Horton, D. R. Langbehn, J. S. Paulsen, J. Lloyd, Leon S. Dure, Christopher Steward, Patricia Desmond, Russell Katz
Publikováno v: Neurotherapeutics. 6:202-212
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86159a893c8dedf5609d7e33ae86e6aa
https://doi.org/10.1016/j.nurt.2008.09.004
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9
Contraction coupling efficiency of human first dorsal interosseous muscle
Autor: Sharon A. Jubrias, Nina K. Vøllestad, Rod K. Gronka, Martin J. Kushmerick
Publikováno v: The Journal of Physiology. 586:1993-2002
During working contractions, chemical energy in the form of ATP is converted to external work. The efficiency of this conversion, called ‘contraction coupling efficiency’, is calculated by the ratio of work output to energy input from ATP splitti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee4b93bcf4709530402f121e2ebfa7c9
https://doi.org/10.1113/jphysiol.2007.146829
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10
Mitochondrial function, fibre types and ageing: new insights from human musclein vivo
Autor: David J. Marcinek, Kevin E. Conley, Sharon A. Jubrias, Catherine E. Amara
Publikováno v: Experimental Physiology. 92:333-339
Mitochondrial changes are at the centre of a wide range of maladies, including diabetes, neurodegeneration and ageing-related dysfunctions. Here we describe innovative optical and magnetic resonance spectroscopic methods that non-invasively measure k
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f52daa6a23173f451110a007a7277ad
https://doi.org/10.1113/expphysiol.2006.034330
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