Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sharon A. Goble"'
Autor:
Brooke R. Daniel, Sharon A. Goble, Mark Keaton, Yvonne Manalo, Linda D. Bosserman, Denise A. Yardley, Martin J. Bury, David Drosick, Victor M. Priego, Howard A. Burris, Donald S. Gravenor, Robyn R. Young, Adam Brufsky, Fred J. Kudrik, Janice F. Eakle, William N. Harwin, Caryn Silver, Roger Inhorn, Jeffrey A. Bubis, John D. Hainsworth, Gladys Rodriguez, Edward Arrowsmith, Kelly Pendergrass
Publikováno v:
Breast Cancer Research and Treatment. 164:649-658
Ixabepilone is a microtubule stabilizer with activity in taxane-refractory metastatic breast cancer and low susceptibility to taxane-resistance mechanisms including multidrug-resistant phenotypes and high β-III tubulin expression. Since these resist
Autor:
Mark Robert Keaton, Howard A. Burris, Brooke R. Daniel, Mary Audrey Ackerman, Denise A. Yardley, Linda D. Bosserman, Emile Salloum, John D. Hainsworth, Sharon A. Goble, Dianna Shipley, William N. Harwin
Publikováno v:
Journal of Clinical Oncology. 33:1000-1000
1000 Background: Ixa is a microtubule stabilizer able to target mechanisms conferring taxane resistance including high b tubulin III expression, seen in TNBC. Here, we present preliminary results o...
Autor:
John D. Hainsworth, H. A. Burris, Brooke R. Daniel, Sharon A. Goble, D. A. Yardley, Paula L. Griner, D. R. Drosick, William N. Harwin, Dianna Shipley, M. A. Ackerman, S. Hanson
Publikováno v:
Journal of Clinical Oncology. 29:1103-1103
1103 Background: Ixabepilone (Ixa) is a potent tubulin polymerizer active in taxane refractory and locally advanced breast cancer as well as in TNBC. The clinical activity and toxicity profile of Ixa are similar to the taxanes with neuropathy and mye