Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Sharon A. George"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Although moderate endurance exercise has been reported to improve cardiovascular health, its effects on cardiac structure and function are not fully characterized, especially with respect to sexual dimorphism. We aimed to assess the effect
Externí odkaz:
https://doaj.org/article/81be6f60bb1d4196bbe1ff2ecebfcce1
Autor:
Anna Gams, Alejandro Nevarez, Stephanie Perkail, Aileen Venegas, Sharon A. George, Tatiana Efimova, Igor R. Efimov
Publikováno v:
Physiological Reports, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract Abnormal heart rate variability (HRV) is commonly observed in cancer patients who have undergone targeted therapy and/or surgery, yet the effects of cancer itself on cardiac function remain underexplored. Specifically, there is limited knowl
Externí odkaz:
https://doaj.org/article/64547d8cd16c4133ae398ea5eda71d25
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Simultaneous triple-parametric optical mapping of transmembrane potential, intracellular calcium, and metabolic markers for cardiac physiology shows that metabolic changes precede the effects of ischemia on cardiac electrophysiology.
Externí odkaz:
https://doaj.org/article/54385f1a69904a2fab04152fd613bd38
Autor:
Joyce Lin, Anand Abraham, Sharon A. George, Amara Greer-Short, Grace A. Blair, Angel Moreno, Bridget R. Alber, Matthew W. Kay, Steven Poelzing
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Many cardiac pathologies are associated with reduced gap junction (GJ) coupling, an important modulator of cardiac conduction velocity (CV). However, the relationship between phenotype and functional expression of the connexin GJ family of proteins i
Externí odkaz:
https://doaj.org/article/b2e5d7cd1ef94b7482db1960752450e2
Publikováno v:
Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Abstract Introduction Doxorubicin (DOX), an anticancer drug used in chemotherapy, causes significant cardiotoxicity. This study aimed to investigate the effects of DOX on mouse cardiac electrophysiology, in conscious versus anesthetized state. Method
Externí odkaz:
https://doaj.org/article/a8aaff9e3db2441ea41cfc468f949b9f
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Background: Tumor Necrosis Factor α (TNFα) upregulation during acute inflammatory response has been associated with numerous cardiac effects including modulating Connexin43 and vascular permeability. This may in turn alter cardiac gap junctional (G
Externí odkaz:
https://doaj.org/article/8e7abd07ef3e421fb7e74e21b6381491
Autor:
Jeffrey Schmeckpeper, Kyungsoo Kim, Sharon A George, Dan Blackwell, Jaclyn A Brennan, Igor R Efimov, Bjorn C Knollmann
BackgroundVentricular tachycardia (VT) is responsible for sudden death in chronic ischemic heart disease (CIHD) patients. The cardiac ryanodine receptor (RyR2) releases Ca2+ from the sarcoplasmic reticulum (SR) and links electrical excitation to cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c888d76c54d2a4c1ab62a67793beb8f
https://doi.org/10.1101/2022.06.24.496861
https://doi.org/10.1101/2022.06.24.496861
Autor:
Joyce, Lin, Anand, Abraham, Sharon A, George, Amara, Greer-Short, Grace A, Blair, Angel, Moreno, Bridget R, Alber, Matthew W, Kay, Steven, Poelzing
Publikováno v:
Frontiers in Physiology. 13
Many cardiac pathologies are associated with reduced gap junction (GJ) coupling, an important modulator of cardiac conduction velocity (CV). However, the relationship between phenotype and functional expression of the connexin GJ family of proteins i
Autor:
Robert E. Simmons, Colleen L. Seymour, Sharon T. George, Koebraa Peters, Frances Morling, M. Justin O’Riain
Publikováno v:
Animals; Volume 13; Issue 6; Pages: 1013
Domestic cats (Felis catus) are amongst the most destructive invasive vertebrates globally, depredating billions of native animals annually. The size and seasonal variation of their geographical “footprint” is key to understanding their effects o
Autor:
Nikita S. D. Sahadeo, Soren Nicholls, Filipe R. R. Moreira, Áine O’Toole, Vernie Ramkissoon, Charles Whittaker, Verity Hill, John T. McCrone, Nicholas Mohammed, Anushka Ramjag, Arianne Brown Jordan, Sarah C. Hill, Risha Singh, Sue-Min Nathaniel-Girdharrie, Avery Hinds, Nuala Ramkissoon, Kris V. Parag, Naresh Nandram, Roshan Parasram, Zobida Khan-Mohammed, Lisa Edghill, Lisa Indar, Aisha Andrewin, Rhonda Sealey-Thomas, Pearl McMillan, Ayoola Oyinloye, Kenneth George, Irad Potter, John Lee, David Johnson, Shawn Charles, Narine Singh, Jacquiline Bisesor-McKenzie, Hazel Laws, Sharon Belmar-George, Simone Keizer-Beache, Sharra Greenaway-Duberry, Nadia Ashwood, Jerome E. Foster, Karla Georges, Rahul Naidu, Marsha Ivey, Stanley Giddings, Rajini Haraksingh, Adesh Ramsubhag, Jayaraj Jayaraman, Chinnaraja Chinnadurai, Christopher Oura, Oliver G. Pybus, Joy St. John, Gabriel Gonzalez-Escobar, Nuno R. Faria, Christine V. F. Carrington
Publikováno v:
PLOS Global Public Health. 3:e0001455
The COVID-19 pandemic highlighted the importance of global genomic surveillance to monitor the emergence and spread of SARS-CoV-2 variants and inform public health decision-making. Until December 2020 there was minimal capacity for viral genomic surv