Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Sharon A. Chen"'
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Epstein-Barr virus (EBV) infection and EBV-associated post-transplant lymphoproliferative disorder (EBV/PTLD) is one of the most devastating complications occurring in pediatric solid organ transplant (SOT) recipients. Observations of SOT recipients
Externí odkaz:
https://doaj.org/article/9bca5d63c9c4441f98fd080d3b03161d
A laboratory framework for ongoing optimization of amplification-based genomic surveillance programs
Autor:
Connie Lam, Jessica Johnson-Mackinnon, Kerri Basile, Winkie Fong, Carl J.E. Suster, Mailie Gall, Jessica Agius, Shona Chandra, Jenny Draper, Elena Martinez, Alexander Drew, Qinning Wang, Sharon C. Chen, Jen Kok, Dominic E. Dwyer, Vitali Sintchenko, Rebecca J. Rockett
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Constantly evolving viral populations affect the specificity of primers and the quality of genomic surveillance. This study presents a framework for the continuous optimization of sequencing efficiency for public health surveillance based on
Externí odkaz:
https://doaj.org/article/c8506cf497274da69108601f2e1d8cca
Autor:
Germaine Wong, Matthew Rowlandson, Dharshana Sabanayagam, Andrew N. Ginn, Kathy Kable, Frederika Sciberras, Eric Au, Jenny Draper, Alicia Arnott, Vitali Sintchenko, Dominic E. Dwyer, Sharon C.A. Chen, Jen Kok
Publikováno v:
Transplantation. 106:1860-1866
Since November 2021, a new variant of concern (VOC), the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage B.1.1.529 (Omicron) has emerged as the dominant coronavirus disease 2019 (COVID-19) infection worldwide. We describe the cli
In 2020, the COVID-19 pandemic caused mandatory lockdowns around the world, which exacerbated mental health issues created by social isolation. To improve museum visitors' mental health and maintain engagement despite the physical closure of museums,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86bc75a63c5cab533758c6d5e4bb4ea2
https://doi.org/10.31234/osf.io/mkges
https://doi.org/10.31234/osf.io/mkges
Autor:
Karen Cornelissen, James G Wright, Andrew Cristinacce, Hal Galbraith, Roger Bruggemann, Johan A Maertens, George R Thompson, Sharon C Chen, John H Rex
Publikováno v:
Open Forum Infectious Diseases. 9
Background OLO is a novel antifungal active vs. Aspergillus (including azole-resistant strains), resistant moulds (e.g., Lomentospora prolificans), and dimorphic moulds. In preclinical PKPD studies, a plasma level ≥ 0.2 µg/mL was required for effi
Autor:
Johan A Maertens, Paul E Verweij, Evan F Lanuza, Emma L Harvey, Aaron Dane, Daniela Zinzi, John H Rex, Sharon C Chen
Publikováno v:
Open Forum Infectious Diseases. 9
Background Olorofim is a novel antifungal agent active against Aspergillus spp (including azole-resistant strains), rare, resistant moulds (e.g., Lomentospora prolificans) and dimorphic moulds. Serial images of Lomentospora prolificans infection foll
Autor:
Johan A Maertens, George R Thompson, Andrej Spec, Sarah P Hammond, Bart Rijnders, P Lewis White, Oliver A Cornely, Lesley Fitton, Aaron Dane, John H Rex, Sharon C Chen
Publikováno v:
Open Forum Infectious Diseases. 9
Background Olorofim, the first orotomide antifungal, selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in fungal pyrimidine biosynthesis. Olorofim is active against Aspergillus (including azole-resistant and cryptic speci
Autor:
Julia S. Bratic, Hayley A. Gans, Sharon F. Chen, Niaz Banaei, Erica M. Johnston, Katherine Sear, Sarah Samreth, Sruti S. Nadimpalli
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsREFERENCES. 22(12)
Pediatric solid organ transplant recipients (pSOTR) often demonstrate suboptimal vaccine responses and are not included in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine efficacy trials. This population has shown variable humora
Publikováno v:
Medical Mycology Case Reports, Vol 7, Iss C, Pp 12-14 (2015)
Immune reconstitution inflammatory syndrome (IRIS) can complicate antifungal treatment of cryptococcosis. There are limited data on managing cryptococcal-associated IRIS. We describe an immunocompetent patient who developed IRIS complicating Cryptoco
Externí odkaz:
https://doaj.org/article/b32e199e43a849a6883bf55039d1c1b9
Autor:
Lauren E. Kushner, Lauren Puckett, Joanne Lee, Torsten Joerger, Sharon F. Chen, Elizabeth Profita
Publikováno v:
Pediatric transplantationREFERENCES. 26(7)