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pro vyhledávání: '"Sharon, Wolda"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 8(2)
cAMP phosphodiesterase (PDE) 4 is a family of enzymes the inhibition of which induces chronic lymphocytic leukemia (CLL) apoptosis. However, leukemic cells from a subset of CLL patients are relatively resistant to treatment with the PDE4 inhibitor ro
Publikováno v:
International Journal of Impotence Research. Aug2005, Vol. 17 Issue 4, p320-325. 6p.
Autor:
Lavery, Danielle L., Davenport, Ian R., Turnbull, Yvonne D., Wheeler, Grant N., Hoppler, Stefan
Publikováno v:
Developmental Dynamics; Mar2008, Vol. 237 Issue 3, p768-779, 12p
Publikováno v:
Cell & Tissue Research; Jun2003, Vol. 312 Issue 3, p301-311, 11p
Publikováno v:
Journal of Neurochemistry; 5/15/2002, Vol. 81 Issue 4, p745-757, 13p, 7 Diagrams
Autor:
Lugnier, Claire
The multigenic family of cyclic nucleotide phosphodiesterases (PDEs) is now known to offer many new therapeutic possibilities through their influence over intracellular signaling, though their precise cell mechanisms to modulating that process remain