Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sharon, Weiss"'
Autor:
Moshe, Katz, Suraj, Subramaniam, Orna, Chomsky-Hecht, Vladimir, Tsemakhovich, Veit, Flockerzi, Enno, Klussmann, Joel A, Hirsch, Sharon, Weiss, Nathan, Dascal
Publikováno v:
Proc Natl Acad Sci U S A
L-type voltage-gated Ca(V)1.2 channels crucially regulate cardiac muscle contraction. Activation of β-adrenergic receptors (β-AR) augments contraction via protein kinase A (PKA)–induced increase of calcium influx through Ca(V)1.2 channels. To dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfe1fbaaeaf5c27c5ae0d16b6afd5c00
https://pubmed.ncbi.nlm.nih.gov/34001616
https://pubmed.ncbi.nlm.nih.gov/34001616
Autor:
Veit Flockerzi, Joel A. Hirsch, Moshe Katz, Vladimir Tsemakhovich, Enno Klussmann, Nathan Dascal, Suraj Subramaniam, Sharon Weiss, Orna Chomsky-Hecht
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Significance The strengthening of heart contraction by epinephrine (adrenaline) and norepinephrine starts with the activation of β-adrenergic receptors and culminates in a protein kinase A–mediated increase in Ca 2+ influx through the voltage-gate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd07fd936cf0ea43eb369f1c79860c90
https://doi.org/10.1073/pnas.2100021118
https://doi.org/10.1073/pnas.2100021118
Autor:
Anouar Belkacemi, Veit Flockerzi, Nathan Dascal, Enno Klussmann, Joel A. Hirsch, Orna Chomsky-Hecht, Vladimir Tsemakhovich, Suraj Subramaniam, Sharon Weiss, Moshe Katz
IntroductionCardiac L-type voltage-gated CaV1.2 channels are crucial in physiological regulation of cardiac excitation-contraction coupling. Adrenergic modulation of CaV1.2 starts with activation of β-adrenergic receptors (AR) and culminates in prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716531c0ead077833279590f7a581ff8
https://doi.org/10.1101/2020.11.30.403964
https://doi.org/10.1101/2020.11.30.403964
Autor:
Sharon Weiss, Masha Gouzman Allouche
Publikováno v:
INTED Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a7541e9ffd91e5ed3bad305bfda11f5
https://doi.org/10.21125/inted.2020.0524
https://doi.org/10.21125/inted.2020.0524
Autor:
Nathan Dascal, Tal Keren Raifman, Prabodh Kumar, Sharon Weiss, Enno Klussmann, Hannelore Haase
Publikováno v:
Channels. 11:604-615
L-type-voltage-dependent Ca2+ channels (L-VDCCs; CaV1.2, α1C), crucial in cardiovascular physiology and pathology, are modulated via activation of G-protein-coupled receptors and subsequently protein kinase C (PKC). Despite extensive study, key aspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bfc68e7353896c3a4b372a8c8e0759
https://doi.org/10.1080/19336950.2017.1369636
https://doi.org/10.1080/19336950.2017.1369636
Autor:
Sharon Weiss, Nathan Dascal
Publikováno v:
Current Molecular Pharmacology. 8:43-53
Ca(2+) influx via L-type Ca(2+) channel (L-VDCC; CaV1.2) is required for cardiac and smooth muscle contraction. These channels are located in the plasma membrane and along the T-tubules (in cardiomyocytes), along with various scaffold and trafficking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede9cd491c922ba9898df0abd5b45a76
https://doi.org/10.2174/1874467208666150507094733
https://doi.org/10.2174/1874467208666150507094733
Publikováno v:
Circulation Research. 113:617-631
In the heart, adrenergic stimulation activates the β-adrenergic receptors coupled to the heterotrimeric stimulatory G s protein, followed by subsequent activation of adenylyl cyclase, elevation of cyclic AMP levels, and protein kinase A (PKA) activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34ca1ac4049c540a088fa179e8bf7283
https://doi.org/10.1161/circresaha.113.301781
https://doi.org/10.1161/circresaha.113.301781
Publikováno v:
Channels
L-type voltage dependent Ca(2+) channels (L-VDCCs; Ca(v)1.2) are crucial in cardiovascular physiology. In heart and smooth muscle, hormones and transmitters operating via G(q) enhance L-VDCC currents via essential protein kinase C (PKC) involvement.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831e2220ccc64b2527f4872b41565058
https://doi.org/10.4161/chan.22016
https://doi.org/10.4161/chan.22016
Autor:
Sharon Weiss, Kenneth Martin, Jeff Schmeckpeper, Noel M. Caplice, Pat Metharom, Arun H.S. Kumar
Publikováno v:
The FASEB Journal. 24:81-92
Smooth muscle cells play a major role in numerous vascular diseases that contribute to remodeling, repair after injury, and arteriogenesis, and the source of these cells is thought to lie within the vessel wall and the circulating blood. Currently, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152c52085c5a0dbf8311cf80dddb35a9
https://doi.org/10.1096/fj.09-132225
https://doi.org/10.1096/fj.09-132225
Autor:
Jeffrey Schmeckpeper, Pat Metharom, Brian G. Hynes, Kenneth Martin, Sharon Weiss, John F. O'Sullivan, Noel M. Caplice
Publikováno v:
Circulation Research. 105:214-218
Rationale: Smooth muscle precursor cells have previously been reported to reside in bone marrow and in the circulation, but little is currently known regarding the proximate stimuli for smooth muscle cell differentiation of these putative progenitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53687e2751beb5cc459ec196896db2f2
https://doi.org/10.1161/circresaha.109.199984
https://doi.org/10.1161/circresaha.109.199984