Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sharon, Wein"'
Autor:
Francis Tsombeng Foguim, Hervé Bogreau, Mathieu Gendrot, Joel Mosnier, Isabelle Fonta, Nicolas Benoit, Rémy Amalvict, Marylin Madamet, Sharon Wein, Bruno Pradines, The French National Reference Centre for Imported Malaria Study Group
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background The Plasmodium falciparum chloroquine transporter gene (pfcrt) is known to be involved in chloroquine and amodiaquine resistance, and more particularly the mutations on the loci 72 to 76 localized within the second exon. Additiona
Externí odkaz:
https://doaj.org/article/14ed6ab795684d71810af423d7157a89
Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites.
Autor:
Elodie Gazanion, Laurent Lacroix, Patrizia Alberti, Pratima Gurung, Sharon Wein, Mingpan Cheng, Jean-Louis Mergny, Ana Rita Gomes, Jose-Juan Lopez-Rubio
Publikováno v:
PLoS Genetics, Vol 16, Iss 7, p e1008917 (2020)
Mechanisms of transcriptional control in malaria parasites are still not fully understood. The positioning patterns of G-quadruplex (G4) DNA motifs in the parasite's AT-rich genome, especially within the var gene family which encodes virulence factor
Externí odkaz:
https://doaj.org/article/ed2703436f1b408ea372dc26315b21b6
Autor:
Sharon Wein, Salma Ghezal, Corinne Buré, Marjorie Maynadier, Christian Périgaud, Henri J. Vial, Isabelle Lefebvre-Tournier, Kai Wengelnik, Rachel Cerdan
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 8, Pp 1461-1471 (2018)
The malaria parasite, Plasmodium falciparum, develops and multiplies in the human erythrocyte. It needs to synthesize considerable amounts of phospholipids (PLs), principally phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylse
Externí odkaz:
https://doaj.org/article/c8065df592284fee86fecc26d411e26d
Autor:
Mohamed D. M. Traoré, Vincent Zwick, Claudia A. Simões-Pires, Alessandra Nurisso, Mark Issa, Muriel Cuendet, Marjorie Maynadier, Sharon Wein, Henri Vial, Helene Jamet, Yung-Sing Wong
Publikováno v:
ACS Omega, Vol 2, Iss 4, Pp 1550-1562 (2017)
Externí odkaz:
https://doaj.org/article/ee61c804c38643ec997c1930494af5e4
Autor:
Sandrine Déchamps, Marjorie Maynadier, Sharon Wein, Laila Gannoun-Zaki, Eric Maréchal, Henri J. Vial
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 1, Pp 81-96 (2010)
Malaria, a disease affecting humans and other animals, is caused by a protist of the genus Plasmodium. At the intraerythrocytic stage, the parasite synthesizes a high amount of phospholipids through a bewildering number of pathways. In the human Plas
Externí odkaz:
https://doaj.org/article/eab8ce0ce7b149c285b260a505c9a289
Autor:
Rachel Cerdan, Thomas Cheviet, Gabriel Bourchenin, Christian Périgaud, Manon Lagacherie, Sharon Wein, Suzanne Peyrottes
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (15), pp.8069-8087. ⟨10.1021/acs.jmedchem.0c00131⟩
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (15), pp.8069-8087. ⟨10.1021/acs.jmedchem.0c00131⟩
Malaria is an infectious disease caused by a parasite of the genus Plasmodium, and the emergence of parasites resistant to all current antimalarial drugs highlights the urgency of having new classes of molecules. We developed an effective method for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bb5fb0627e01d1b5ef2a25164b9ae0
https://hal.archives-ouvertes.fr/hal-03007532
https://hal.archives-ouvertes.fr/hal-03007532
Autor:
Thomas, Cheviet, Sharon, Wein, Gabriel, Bourchenin, Manon, Lagacherie, Christian, Périgaud, Rachel, Cerdan, Suzanne, Peyrottes
Publikováno v:
Journal of medicinal chemistry. 63(15)
Malaria is an infectious disease caused by a parasite of the genus
Autor:
Jean-Louis Mergny, Laurent Lacroix, Patrizia Alberti, Jose-Juan Lopez-Rubio, Ana Rita Gomes, Pratima Gurung, Elodie Gazanion, Mingpan Cheng, Sharon Wein
Publikováno v:
PLoS Genetics
PLoS Genetics, Public Library of Science, 2020, 16 (7), pp.e1008917. ⟨10.1371/journal.pgen.1008917⟩
PLoS Genetics, 2020, 16 (7), pp.e1008917. ⟨10.1371/journal.pgen.1008917⟩
PLoS Genetics, Vol 16, Iss 7, p e1008917 (2020)
PLoS Genetics, Public Library of Science, 2020, 16 (7), pp.e1008917. ⟨10.1371/journal.pgen.1008917⟩
PLoS Genetics, 2020, 16 (7), pp.e1008917. ⟨10.1371/journal.pgen.1008917⟩
PLoS Genetics, Vol 16, Iss 7, p e1008917 (2020)
Mechanisms of transcriptional control in malaria parasites are still not fully understood. The positioning patterns of G-quadruplex (G4) DNA motifs in the parasite’s AT-rich genome, especially within the var gene family which encodes virulence fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e793c625a2e9c253e09b61361deb25
https://hal.umontpellier.fr/hal-03152243
https://hal.umontpellier.fr/hal-03152243
Autor:
Claudia A. Simões-Pires, Yung-Sing Wong, Mohamed Dit Mady Traoré, Vincent Zwick, Sharon Wein, Muriel Cuendet, Marjorie Maynadier, Mark E. Issa, Alessandra Nurisso, Henri Vial, Hélène Jamet
Publikováno v:
ACSOmega
ACS Omega
ACS Omega, Vol. 2, No 4 (2017) pp. 1550-1562
ACS Omega, Vol 2, Iss 4, Pp 1550-1562 (2017)
ACS Omega, ACS Publications, 2017, 2 (4), pp.1550-1562. ⟨10.1021/acsomega.6b00481⟩
ACS Omega
ACS Omega, Vol. 2, No 4 (2017) pp. 1550-1562
ACS Omega, Vol 2, Iss 4, Pp 1550-1562 (2017)
ACS Omega, ACS Publications, 2017, 2 (4), pp.1550-1562. ⟨10.1021/acsomega.6b00481⟩
Little is known about the biological and structural features that govern the isoform selectivity for class I histone deacetylases (HDACs) over HDAC6. In addition to that for known inhibitors, like benzamides, psammaplin A, and cyclodepsipeptide-deriv
Autor:
Sharon Wein, Thierry Durand, Françoise Bressolle, Séverine Denoyelle, Olivier Berger, Stéphanie Ortial, Henri Vial, Roger Escale, Yen Vo-Hoang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
Bioorganic & Medicinal Chemistry Letters, 2019, 29, pp.2203-2207. ⟨10.1016/j.bmcl.2019.06.045⟩
Bioorganic & Medicinal Chemistry Letters, 2019, 29, pp.2203-2207. ⟨10.1016/j.bmcl.2019.06.045⟩
Plasmodium falciparum is responsible for most of the cases of malaria and its resistance to established antimalarial drugs is a major issue. Thus, new chemotherapies are needed to fight the emerging multi-drug resistance of P. falciparum malaria, lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a801545a0604ede7f74093c0524614a
https://hal.archives-ouvertes.fr/hal-03488325
https://hal.archives-ouvertes.fr/hal-03488325