Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Sharon, O'Toole"'
Autor:
Joanna Lazniewska, Ka Lok Li, Ian R. D. Johnson, Alexandra Sorvina, Jessica M. Logan, Carmela Martini, Courtney Moore, Ben S.-Y. Ung, Litsa Karageorgos, Shane M. Hickey, Sarita Prabhakaran, Jessica K. Heatlie, Robert D. Brooks, Chelsea Huzzell, Nicholas I. Warnock, Mark P. Ward, Bashir Mohammed, Prerna Tewari, Cara Martin, Sharon O’Toole, Laura Bogue Edgerton, Mark Bates, Paul Moretti, Stuart M. Pitson, Stavros Selemidis, Lisa M. Butler, John J. O’Leary, Douglas A. Brooks
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Prostate cancer (PCa) development and progression relies on the programming of glucose and lipid metabolism, and this involves alterations in androgen receptor expression and signalling. Defining the molecular mechanism that underpins this m
Externí odkaz:
https://doaj.org/article/50253ef611194e4595e03d647adf9305
Autor:
Bashir M. Mohamed, Mark P. Ward, Mark Bates, Cathy D. Spillane, Tanya Kelly, Cara Martin, Michael Gallagher, Sheena Heffernan, Lucy Norris, John Kennedy, Feras Abu Saadeh, Noreen Gleeson, Doug A. Brooks, Robert D. Brooks, Stavros Selemidis, Sharon O’Toole, John J. O’Leary
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Circulating tumour cells (CTCs) are a critical intermediate step in the process of cancer metastasis. The reliability of CTC isolation/purification has limited both the potential to report on metastatic progression and the development of CTC
Externí odkaz:
https://doaj.org/article/8a0eceb23e854e889f86fef99c3b1ed3
Autor:
Jennifer Fortune, Jessica Burke, Conor Dillon, Sally Dillon, Sharon O’Toole, Ann Enright, Annmarie Flynn, Manjula Manikandan, Thilo Kroll, Grace Lavelle, Jennifer M. Ryan
Publikováno v:
Frontiers in Rehabilitation Sciences, Vol 3 (2022)
IntroductionDesign thinking is a human-centred process that aims to identify the needs of end-users and iteratively develop solutions. Involving end-users in the development and design of solutions may enhance effectiveness by increasing focus on the
Externí odkaz:
https://doaj.org/article/78c9dd071c1e480a9f9048a59964d801
Autor:
Osezua Oseghale, Stella Liong, Madison Coward-Smith, Eunice E To, Jonathan R Erlich, Raymond Luong, Felicia Liong, Mark Miles, Shaghayegh Norouzi, Cara Martin, Sharon O'Toole, Robert D Brooks, Steven Bozinovski, Ross Vlahos, John J O'Leary, Doug A Brooks, Stavros Selemidis
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8, p e1010703 (2022)
Influenza A virus (IAV) infection during pregnancy initiates significant aortic endothelial and vascular smooth muscle dysfunction, with inflammation and T cell activation, but the details of the mechanism are yet to be clearly defined. Here we demon
Externí odkaz:
https://doaj.org/article/87939b1b8d0043309e5d3dfd59bd4e58
Autor:
Roshni D. Kalachand, Ciaran O’Riain, Sinead Toomey, Aoife Carr, Kirsten M. Timms, Sharon O’Toole, Stephen Madden, Mark Bates, John J. O’Leary, Noreen Gleeson, Dearbhaile O’Donnell, Liam Grogan, Oscar Breathnach, Angela Farrelly, Britta Stordal, Bryan T. Hennessy
Publikováno v:
Obstetrics & Gynecology Science, Vol 63, Iss 5, Pp 643-654 (2020)
Objective The therapeutic benefits of poly(ADP-ribose) polymerase inhibitors highlight the need to evaluate BRCA1/2 defects in tubal/ovarian cancer (OC). We sought to determine the pattern and disease characteristics associated with tumor BRCA1/2 mut
Externí odkaz:
https://doaj.org/article/6cbb4fc095ea435da4eec3de790092e5
Autor:
Sarah Cooper, Tomás P. Carroll, Laura Gorman, Ann Cullen, Blánaid Mee, Billy McCann, Verena Murphy, Nicola Miller, Jackie O'Leary, Máiréad Murray, Niamh Clarke, Emma Snapes, Sharon O'Toole, Lydia O'Sullivan, Suzanne Bracken
Publikováno v:
HRB Open Research, Vol 4 (2022)
Biobanks are repositories of human biological samples and data. They are an important component of clinical research in many disease areas and often represent the first step toward innovative treatments. For biobanks to operate, researchers need huma
Externí odkaz:
https://doaj.org/article/f94d1368c55e45b0bcd2d85aa4e67444
Autor:
Bincy Jose, Rajani K. Vijayaraghavan, Lorcan Kent, Sharon O'Toole, John O'Leary, Robert J. Forster
Publikováno v:
Electrochemistry Communications, Vol 98, Iss , Pp 106-109 (2019)
The use of two-photon 3D printing to create templates for fabricating reproducible and tunable metallic nanostructures is described. The approach allows the structure of the template to be designed specifically for particular applications, e.g., flui
Externí odkaz:
https://doaj.org/article/651dcb0bbc684a68bbb768991953cf33
Autor:
Mark Bates, Cathy D Spillane, Michael F Gallagher, Amanda McCann, Cara Martin, Gordon Blackshields, Helen Keegan, Luke Gubbins, Robert Brooks, Doug Brooks, Stavros Selemidis, Sharon O'Toole, John J O'Leary
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243715 (2020)
Despite the use of front-line anticancer drugs such as paclitaxel for ovarian cancer treatment, mortality rates have remained almost unchanged for the past three decades and the majority of patients will develop recurrent chemoresistant disease which
Externí odkaz:
https://doaj.org/article/1b4173fb417c4b46a697ca0c7cfb267a
Autor:
Joanna Lazniewska, Ka Lok Li, Ian Johnson, Alexandra Sorvina, Jessica Logan, Carmela Martini, Courtney Moore, Ben Ung, Litsa Karageorgos, Sarita Prabhakaran, Jessica Heatlie, Robert Brooks, Shane Hickey, Chelsea Huzzell, Nicholas Warnock, Mark Ward, Bashir Mohammed, Prerna Tewari, Cara Martin, Sharon O'Toole, Laura Bogue Edgerton, Mark Bates, Paul Moretti, Stuart Pitson, Stavros Selemidis, Lisa Butler, John O'Leary, Douglas Brooks
Prostate cancer (PCa) development and progression relies on the programming of glucose and lipid metabolism, and this involves alterations in androgen receptor expression and signalling. Defining the molecular mechanism that underpins this metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19b5df1fe8c001595b38ee858101225c
https://doi.org/10.21203/rs.3.rs-2693853/v1
https://doi.org/10.21203/rs.3.rs-2693853/v1
Publikováno v:
Thrombosis Research. 207:25-32
Objective Gynaecological cancer surgery is associated with high rates of venous thromboembolism (VTE) despite recommended prophylaxis. We sought to investigate the impact of extended prophylaxis with fixed dose and weight based LMWH in patients under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd41766f8f0e728b4bdd8db8ceef608
https://doi.org/10.1016/j.thromres.2021.08.027
https://doi.org/10.1016/j.thromres.2021.08.027