Výsledky vyhledávání - "Sharon, Kafka"

Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonists

Autor: James A, Hendrix, Stephen J, Shimshock, Gregory M, Shutske, John D, Tomer, Kevin J, Kapples, Mark G, Palermo, Thomas J Roy, Corbett, Hugo M, Vargas, Sharon, Kafka, Karen M, Brooks, Lynn, Laws-Ricker, David K H, Lee, Inez, de Lannoy, Michel, Bordeleau, Geihan, Rizkalla, Joshua, Owolabi, Rajender K, Kamboj

Publikováno v: Chembiochem : a European journal of chemical biology. 3(10)

A new class of potent dopamine D(4) antagonists was discovered with selectivity over dopamine D(2) and the alpha-1 adrenoceptor. The lead compound was discovered by screening our compound collection. The structure-activity relationships of substitute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff30dd173494c1d430b6e14da77e12fa
https://pubmed.ncbi.nlm.nih.gov/12362366

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