Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sharon, Bisaha"'
Autor:
Saleem, Ahmad, William N, Washburn, Andres S, Hernandez, Sharon, Bisaha, Khehyong, Ngu, Wei, Wang, Mary Ann, Pelleymounter, Daniel, Longhi, Neil, Flynn, Anthony V, Azzara, Kenneth, Rohrbach, James, Devenny, Suzanne, Rooney, Michael, Thomas, Susan, Glick, Helen, Godonis, Susan, Harvey, Hongwei, Zhang, Brian, Gemzik, Evan B, Janovitz, Christine, Huang, Lisa, Zhang, Jeffrey A, Robl, Brian J, Murphy
Publikováno v:
Journal of medicinal chemistry. 59(19)
The potent MCHR1 in vitro and in vivo antagonist activity of a series of cyclic tertiary alcohols derived from compound 2b is described. Subsequent pharmacokinetic and pharmacodynamic studies identified BMS-814580 (compound 10) as a highly efficaciou
Autor:
Natesan Murugesan, Zhengxiang Gu, Philip D. Stein, Sharon Bisaha, Steve Spergel, Ravi Girotra, Ving G. Lee, John Lloyd, Raj N. Misra, Joan Schmidt, Arvind Mathur, Leslie Stratton, Yolanda F. Kelly, Eileen Bird, Tom Waldron, Eddie C.-K. Liu, Rongan Zhang, Helen Lee, Randy Serafino, Benoni Abboa-Offei, Parker Mathers, Mary Giancarli, Andrea Ann Seymour, Maria L. Webb, Suzanne Moreland, Joel C. Barrish, John T. Hunt
Publikováno v:
Journal of Medicinal Chemistry. 41:5198-5218
Substitution at the ortho position of N-(3,4-dimethyl-5-isoxazolyl) benzenesulfonamide led to the identification of the biphenylsulfonamides as a novel series of endothelin-A (ETA) selective antagonists. Appropriate substitutions on the pendant pheny
Autor:
Saleem Ahmad, Cort S. Madsen, Philip D. Stein, Evan Janovitz, Christine Huang, Khehyong Ngu, Sharon Bisaha, Lawrence J. Kennedy, Bang-Chi Chen, Rulin Zhao, Doree Sitkoff, Hossain Monshizadegan, Xiaohong Yin, Carol S. Ryan, Rongan Zhang, Mary Giancarli, Eileen Bird, Ming Chang, Xing Chen, Robert Setters
Publikováno v:
Journal of Medicinal Chemistry; Apr2008, Vol. 51 Issue 9, p2722-2733, 12p