Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sharmina Miller"'
Autor:
Pabitra K. Sahoo, Seung Joon Lee, Poonam B. Jaiswal, Stefanie Alber, Amar N. Kar, Sharmina Miller-Randolph, Elizabeth E. Taylor, Terika Smith, Bhagat Singh, Tammy Szu-Yu Ho, Anatoly Urisman, Shreya Chand, Edsel A. Pena, Alma L. Burlingame, Clifford J. Woolf, Mike Fainzilber, Arthur W. English, Jeffery L. Twiss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
G3BP1 is RasGAP SH3 domain binding protein 1 that interacts with 48S pre-initiation complex when translation is stalled. Here, Twiss and colleagues show that neuronal G3BP1 can negatively regulate axonal mRNA translation, and inhibit axonal regenerat
Externí odkaz:
https://doaj.org/article/54f17aef7ce54eff8c30573b11316ce9
Autor:
Zachary L Newman, Morton P Printz, Shihui Liu, Devorah Crown, Laura Breen, Sharmina Miller-Randolph, Pamela Flodman, Stephen H Leppla, Mahtab Moayeri
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000906 (2010)
Anthrax lethal toxin (LT) is a bipartite protease-containing toxin and a key virulence determinant of Bacillus anthracis. In mice, LT causes the rapid lysis of macrophages isolated from certain inbred strains, but the correlation between murine macro
Externí odkaz:
https://doaj.org/article/49fdeb7fc0964a4d91268c48cb24194f
Autor:
Priyanka Patel, Courtney N Buchanan, Matthew D Zdradzinski, Pabitra K Sahoo, Amar N Kar, Seung Joon Lee, Lauren S Vaughn, Anatoly Urisman, Juan Oses-Prieto, Michela Dell’Orco, Devon E Cassidy, Irene Dalla Costa, Sharmina Miller, Elizabeth Thames, Terika P Smith, Alma L Burlingame, Nora Perrone-Bizzozero, Jeffery L Twiss
Publikováno v:
Nucleic acids research. 50(10)
Axonally synthesized proteins support nerve regeneration through retrograde signaling and local growth mechanisms. RNA binding proteins (RBP) are needed for this and other aspects of post-transcriptional regulation of neuronal mRNAs, but only a limit
Autor:
Ashutosh Arora, Blake Jones, Austin Lewis, Sharmina Miller-Randolph, Jeffery Twiss, Pabitra Sahoo
Publikováno v:
Journal of Biological Chemistry. 299:104276
Autor:
Anatoly Urisman, Devon E. Cassidy, Courtney N Buchanan, Elizabeth Thames, Priyanka Patel, Terika P. Smith, Amar N. Kar, Seung Joon Lee, Michela Dell’Orco, Nora Perrone-Bizzozero, Jeffery L. Twiss, Juan A. Oses-Prieto, Pabitra K. Sahoo, Alma L. Burlingame, Sharmina Miller, Matthew D. Zdradzinski
Proteins generated by localized mRNA translation in axons support nerve regeneration through retrograde injury signaling and localized axon growth mechanisms. RNA binding proteins (RBP) are needed for this and other aspects of post-transcriptional co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e108920025afc89016486d81dcb3c3e7
https://doi.org/10.1101/2020.10.26.356162
https://doi.org/10.1101/2020.10.26.356162
Autor:
Riki Kawaguchi, Jeffery L. Twiss, David Oliver, Amar N. Kar, Pabitra K. Sahoo, Meir Rozenbaum, Ross J. Taylor, Alma L. Burlingame, Michael Shtutman, Seung Joon Lee, Hao Ji, Juan A. Oses-Prieto, Sharmina Miller-Randolph, Shreya Chand, Giovanni Coppola, Mike Fainzilber
Publikováno v:
Molecular & cellular proteomics : MCP, vol 17, iss 11
mRNA translation in axons enables neurons to introduce new proteins at sites distant from their cell body. mRNA-protein interactions drive this post-transcriptional regulation, yet knowledge of RNA binding proteins (RBP) in axons is limited. Here we
Autor:
Clifford J. Woolf, Edsel A. Peña, Stefanie Alber, Poonam B. Jaiswal, Alma L. Burlingame, Terika P. Smith, Jeffery L. Twiss, Amar N. Kar, Elizabeth E. Taylor, Arthur W. English, Pabitra K. Sahoo, Mike Fainzilber, Anatoly Urisman, Shreya Chand, Seung Joon Lee, Sharmina Miller-Randolph, Tammy Szu-Yu Ho, Bhagat Singh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature communications, vol 9, iss 1
Nature Communications
Nature communications, vol 9, iss 1
Nature Communications
Critical functions of intra-axonally synthesized proteins are thought to depend on regulated recruitment of mRNA from storage depots in axons. Here we show that axotomy of mammalian neurons induces translation of stored axonal mRNAs via regulation of
Autor:
Mike Fainzilber, Pabitra K. Sahoo, Marco Terenzio, Elizabeth Thames, Seung Joon Lee, Amar N. Kar, Blake N. Jones, Nitzan Samra, Giovanni Coppola, Jeffery L. Twiss, Riki Kawaguchi, Priyanka Patel, Sharmina Miller
Publikováno v:
SSRN Electronic Journal.
The main limitation on axon regeneration in the peripheral nervous system (PNS) is the slow rate of regrowth. We recently demonstrated that nerve regeneration can be accelerated by axonal G3BP1 aggregate disassembly, releasing axonal mRNAs for local
Autor:
Priyanka Patel, Amar N. Kar, Giovanni Coppola, Elizabeth Thames, Mike Fainzilber, Pabitra K. Sahoo, Jeffery L. Twiss, Marco Terenzio, Blake N. Jones, Nitzan Samra, Riki Kawaguchi, Seung Joon Lee, Sharmina Miller
Publikováno v:
Current Biology. 30:4882-4895.e6
The main limitation on axon regeneration in the peripheral nervous system (PNS) is the slow rate of regrowth. We recently reported that nerve regeneration can be accelerated by axonal G3BP1 granule disassembly, releasing axonal mRNAs for local transl
Autor:
Sharmina Miller-Randolph, Andrew P. Tosolini, Ryan Passino, Victor Wong, Giampietro Schiavo, Leif A. Havton, Roman J. Giger, James N. Sleigh, Amar N. Kar, Alicia L. Hawthorne, Paul Brito-Vargas, Cristina Picci, Seung Joon Lee, Jeffery L. Twiss, Deanna S. Smith, Brett Langley, John Craver, Liang Shi, Ashley L. Kalinski, Dianna E. Willis
Publikováno v:
The Journal of Cell Biology
Van Den Bosch highlights the discovery by Kalinski et al. of Miro1 as an HDAC6 substrate that regulates mitochondrial trafficking in neurons and axon regeneration.
Myelin-associated glycoprotein and chondroitin sulfate proteoglycans in the extra
Myelin-associated glycoprotein and chondroitin sulfate proteoglycans in the extra