Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Sharmili Vidyadaran"'
Autor:
Mohd Amir Kamaruzzaman, Muhammad Hibatullah Romli, Razif Abas, Sharmili Vidyadaran, Mohamad Taufik Hidayat Baharuldin, Muhammad Luqman Nasaruddin, Vishnumukkala Thirupathirao, Sreenivasulu Sura, Kabul Warsito, Nurul Huda Mohd Nor, Muhammad Amsyar Azwaruddin, Mohammed Abdullah Alshawsh, Mohamad Aris Mohd Moklas
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objective: Over the last decade, researchers have sought to develop novel medications against dementia. One potential agent under investigation is cannabinoids. This review systematically appraised and meta-analyzed published pre-clinical research on
Externí odkaz:
https://doaj.org/article/3be6d49afeb049a39e0cce8e764df2c2
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2648 (2023)
(1) Background: The latest research illustrates that microglia phenotype is not the binary ‘resting’ and ‘activated’ profiles. Instead, there is wide diversity in microglia states. Similarly, when testing different stimulation protocols for B
Externí odkaz:
https://doaj.org/article/9df852dea14b4333850d0b7e2468d1a0
Autor:
Han-Chung Lee, Hamizun Hamzah, Melody Pui-Yee Leong, Hadri Md Yusof, Omar Habib, Shahidee Zainal Abidin, Eryse Amira Seth, Siong-Meng Lim, Sharmili Vidyadaran, Mohamad Aris Mohd Moklas, Maizaton Atmadini Abdullah, Norshariza Nordin, Zurina Hassan, Pike-See Cheah, King-Hwa Ling
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Ruxolitinib is the first janus kinase 1 (JAK1) and JAK2 inhibitor that was approved by the United States Food and Drug Administration (FDA) agency for the treatment of myeloproliferative neoplasms. The drug targets the JAK/STAT signalling pa
Externí odkaz:
https://doaj.org/article/b2cbcfa33d8b42fb93d9fbc95b27e345
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Phyllanthus amarus has been shown to attenuate lipopolysaccharide (LPS)-induced peripheral inflammation but similar studies in the central nervous system are scarce. The aim of the present study was to investigate the neuroprotect
Externí odkaz:
https://doaj.org/article/06124897944948a8bfb92155498e1355
Autor:
Neeranjini Nallathamby, Hariprasath Lakshmanan, Sharmili Vidyadaran, Sri Nurestri Abdul Malek, Chia-Wei Phan, Vikineswary Sabaratnam
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020)
Lignosus rhinocerotis (tiger milk mushroom) is widely used by the indigenous people of Malaysia as a traditional remedy. The present study was carried out in order to evaluate the antioxidant, cytotoxic and anti-neuroinflammatory activities of L. rhi
Externí odkaz:
https://doaj.org/article/8a72f7064e4b454886d01ac865da9cf2
Autor:
Maryam Maqbool, Satar Jabbar Rahi Algraittee, Mohadese Hashem Boroojerdi, Vahid Hosseinpour Sarmadi, Cini Mathew John, Sharmili Vidyadaran, Rajesh Ramasamy
Publikováno v:
Innate Immunity, Vol 26 (2019)
Although monocytes represent an essential part of the host defence system, their accumulation and prolonged stimulation could be detrimental and may aggravate chronic inflammatory diseases. The present study has explored the less-understood immunomod
Externí odkaz:
https://doaj.org/article/0246ce4d34354f2fb06c97948d3a8d56
Autor:
Noor Aishah Mohammed Izham, Jasmine Siew Min Chia, Sharmili Vidyadaran, Mohd Roslan Sulaiman, B. Hemabarathy Bharatham, Enoch Kumar Perimal
Publikováno v:
Life Sciences, Medicine and Biomedicine, Vol 2, Iss 3 (2018)
The human neuroblastoma cell line, SH-SY5Y cells, is commonly used as an in vitro model for neuroscience and neurobiology research. SH-SY5Y cells were established during the 1970’s from the parental metastatic bone tumor, SK-N-SH cell line. The uti
Externí odkaz:
https://doaj.org/article/719eaa8fe98440b89915acbb0e24b111
Publikováno v:
Biomedicines, Vol 5, Iss 4, p 68 (2017)
Astrocytes are known as structural and supporting cells in the central nervous system (CNS). Glutamate, as a main excitatory amino acid neurotransmitter in the mammalian central nervous system, can be excitotoxic, playing a key role in many chronic n
Externí odkaz:
https://doaj.org/article/7f72c8b565d143b7b4fe82a5af2caa8d
Publikováno v:
Exp Biol Med (Maywood)
Nitric oxide is a versatile mediator formed by enzymes called nitric oxide synthases. It has numerous homeostatic functions and important roles in inflammation. Within the inflamed brain, microglia and astrocytes produce large amounts of nitric oxide
Autor:
Rajesh Ramasamy, Satar Jabbar Rahi Algraittee, Mohadese Hashem Boroojerdi, Sharmili Vidyadaran, Vahid Hosseinpour Sarmadi, Cini Mathew John, Maryam Maqbool
Publikováno v:
Innate Immunity
Innate Immunity, Vol 26 (2019)
Innate Immunity, Vol 26 (2019)
Although monocytes represent an essential part of the host defence system, their accumulation and prolonged stimulation could be detrimental and may aggravate chronic inflammatory diseases. The present study has explored the less-understood immunomod