Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sharmila Venugopal"'
Autor:
Vada Andree Furlan, Daria MacAuslan, Khiem Ha, Nitish Patel, Shawn Adam, Beylem Zanagar, Sharmila Venugopal
Publikováno v:
Neuroglia, Vol 5, Iss 2, Pp 119-128 (2024)
Neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are clinically distinct, yet share synaptic dysfunction as a common brain pathophysiology. Neurodegenerative diseases such as Hunt
Externí odkaz:
https://doaj.org/article/8a71732f128845b4bfe2b6affea272e6
Autor:
Sharmila Venugopal, Zohal Ghulam-Jhelani, In Sook Ahn, Xia Yang, Martina Wiedau, Dwayne Simmons, Scott H. Chandler
Publikováno v:
Neurobiology of Disease, Vol 177, Iss , Pp 105992- (2023)
Amyotrophic Lateral Sclerosis (ALS) involves protracted pre-symptomatic periods of abnormal motor neuron (MN) excitability occurring in parallel with central and peripheral synaptic perturbations. Focusing on inhibitory control of MNs, we first compa
Externí odkaz:
https://doaj.org/article/38a64488b867408eb05971fb6145ea22
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 12, p e1009644 (2021)
Peristalsis, the coordinated contraction-relaxation of the muscles of the stomach is important for normal gastric motility and is impaired in motility disorders. Coordinated electrical depolarizations that originate and propagate within a network of
Externí odkaz:
https://doaj.org/article/73106c2e7ba049b7859973d2a52e5c2c
Autor:
Wenting Liu, Sharmila Venugopal, Sana Majid, In Sook Ahn, Graciel Diamante, Jason Hong, Xia Yang, Scott H. Chandler
Publikováno v:
Neurobiology of Disease, Vol 141, Iss , Pp 104877- (2020)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease in which motor neurons throughout the brain and spinal cord progressively degenerate resulting in muscle atrophy, paralysis and death. Recent studies using animal models of ALS implic
Externí odkaz:
https://doaj.org/article/384abdbbc8454564895a7c0c6ceb95c6
Autor:
Sharmila Venugopal, Soju Seki, David H Terman, Antonios Pantazis, Riccardo Olcese, Martina Wiedau-Pazos, Scott H Chandler
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 6, p e1007154 (2019)
Neurons utilize bursts of action potentials as an efficient and reliable way to encode information. It is likely that the intrinsic membrane properties of neurons involved in burst generation may also participate in preserving its temporal features.
Externí odkaz:
https://doaj.org/article/9be6bbeeb4bc43f49cc3eca91cea0662
Publikováno v:
Encyclopedia of Computational Neuroscience ISBN: 9781461473206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bf26187ccf833d5d462df7b0755e17
https://doi.org/10.1007/978-1-0716-1006-0_100695
https://doi.org/10.1007/978-1-0716-1006-0_100695
Pre-symptomatic studies in mouse models of the neurodegenerative motor neuron (MN) disease, Amyotrophic Lateral Sclerosis (ALS) highlight early alterations in intrinsic and synaptic excitability and have supported an excitotoxic theory of MN death. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a37da43cea7604acebccf5fa786d5893
https://doi.org/10.1101/2021.12.16.473041
https://doi.org/10.1101/2021.12.16.473041
Autor:
Riccardo Olcese, Igor Spigelman, Sharmila Venugopal, Scott H. Chandler, Martina Wiedau-Pazos, Toru Yamamoto, Kiara Quinn, Soju Seki, Antonios Pantazis
Publikováno v:
The Journal of Neuroscience. 39:8798-8815
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease in which motor neurons degenerate, resulting in muscle atrophy, paralysis, and fatality. Studies using mouse models of ALS indicate a protracted period of disease development with pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e47af76136c6fd3141df46fd4e497141
https://doi.org/10.1523/jneurosci.1214-19.2019
https://doi.org/10.1523/jneurosci.1214-19.2019
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 12, p e1009644 (2021)
PLoS Computational Biology, Vol 17, Iss 12, p e1009644 (2021)
Peristalsis, the coordinated contraction—relaxation of the muscles of the stomach is important for normal gastric motility and is impaired in motility disorders. Coordinated electrical depolarizations that originate and propagate within a network o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4109d82e949db4e02f23f6486275be88
https://pubmed.ncbi.nlm.nih.gov/34871315
https://pubmed.ncbi.nlm.nih.gov/34871315