Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sharmila Nair"'
Autor:
Sharmila Nair, Luciano Mazzoccoli, Arijita Jash, Jennifer Govero, Sachendra S. Bais, Tong Hu, Camila R. Fontes-Garfias, Chao Shan, Hideho Okada, Sujan Shresta, Jeremy N. Rich, Pei-Yong Shi, Michael S. Diamond, Milan G. Chheda
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
Glioblastoma multiforme (GBM) is a fatal human cancer in part because GBM stem cells are resistant to therapy and recurrence is inevitable. Previously, we demonstrated Zika virus (ZIKV) targets GBM stem cells and prevents death of mice with gliomas.
Externí odkaz:
https://doaj.org/article/cc0774b684754a278d9b7e4db97ef179
Autor:
Sharmila Nair, Kristin Michaelsen-Preusse, Katja Finsterbusch, Sabine Stegemann-Koniszewski, Dunja Bruder, Martina Grashoff, Martin Korte, Mario Köster, Ulrich Kalinke, Hansjörg Hauser, Andrea Kröger
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1003999 (2014)
The innate immune system protects cells against invading viral pathogens by the auto- and paracrine action of type I interferon (IFN). In addition, the interferon regulatory factor (IRF)-1 can induce alternative intrinsic antiviral responses. Althoug
Externí odkaz:
https://doaj.org/article/4dfad22e1beb411696a0d2407fd0e664
Autor:
Broc T. McCune, Annette Robichaud, Shamus P. Keeler, Natasha M. Kafai, Adam L. Bailey, Richard D. Head, Julie M. Fox, Sharmila Nair, Jinsheng Yu, Michael S. Diamond, Rita E. Chen, Liang I. Kang, James T. Earnest, Sarah Dort, Michael J. Holtzman, Jon H. Ritter, Emma S. Winkler
Publikováno v:
Nature Immunology
Nature immunology
Nature immunology
Although animal models have been evaluated for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, none have fully recapitulated the lung disease phenotypes seen in humans who have been hospitalized. Here, we evaluate transgenic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec14b98b901bb86331fa418c0e022b1b
https://doi.org/10.1038/s41590-020-0778-2
https://doi.org/10.1038/s41590-020-0778-2
Publikováno v:
Malaysian Online Journal of Educational Management. 8:82-102
Financial literacy is an important but often ignored skill that is vital for the young. Lack of knowledge and understanding of financial literacy will directly affect the well-being of the individual. Research indicates that due to low financial lite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be7ca2d84af8e28808209d10c9232ce5
https://doi.org/10.22452/mojem.vol8no3.5
https://doi.org/10.22452/mojem.vol8no3.5
Autor:
Ashwani Kesarwani, Sachendra Singh Bais, Sharmila Nair, Amanda Andrade De Costa, Tong Hu, Pei-Yong Shi, Michael S Diamond, Milan G Chheda
Publikováno v:
Neuro-Oncology. 24:vii214-vii214
We are developing ZIKV as a therapy for GBM. We previously demonstrated ZIKV specifically kills GBM stem cells. Using GL261 and CT2A mouse models, ZIKV induces a CD8+ T-cell mediated anti-tumor response and leads to 65% and 40% long term survivors, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4370a7cbebf07aadc4a374de6bb7b48
https://doi.org/10.1093/neuonc/noac209.821
https://doi.org/10.1093/neuonc/noac209.821
Publikováno v:
Journal of Pediatric Health Care. 33:296-308
Introduction Asthma is underdiagnosed, particularly for children younger than 5 years old. Clinical practice guidelines have been shown to improve asthma diagnosis and management, but are underutilized. This evidence-based practice project aimed to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff605a470302ed7e54894e642675d07
https://doi.org/10.1016/j.pedhc.2018.10.003
https://doi.org/10.1016/j.pedhc.2018.10.003
Autor:
Tong Hu, Luciano Mazzoccoli, Jeremy N. Rich, Sachendra S. Bais, Michael S. Diamond, Milan G. Chheda, Hideho Okada, Pei Yong Shi, Arijita Jash, Jennifer Govero, Camila R. Fontes-Garfias, Sujan Shresta, Sharmila Nair, Chao Shan
Publikováno v:
JCI insight, vol 6, iss 1
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
Glioblastoma multiforme (GBM) is a fatal human cancer in part because GBM stem cells are resistant to therapy and recurrence is inevitable. Previously, we demonstrated Zika virus (ZIKV) targets GBM stem cells and prevents death of mice with gliomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70a1ddc1d5cb1ac10ad87cd9a425e2b
https://escholarship.org/uc/item/00x665sr
https://escholarship.org/uc/item/00x665sr
Autor:
Pei Yong Shi, Michael P. Diamond, Luciano Mazzoccoli, Sujan Shresta, Sharmila Nair, Milan G. Chheda, Jeremy N. Rich, Tong Hu, Arijita Jash, Jennifer Govero
Publikováno v:
Neuro Oncol
GBM is a hallmark example of an immunotherapy-resistant tumor. Previously, we discovered that Zika virus (ZIKV) has a natural honing capacity to specifically kill GBM stem cells (GSCs). Using two syngeneic glioma models, GL261 and CT2A, we found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855625f38ba3c6f6bd2a397755514743
https://europepmc.org/articles/PMC7651684/
https://europepmc.org/articles/PMC7651684/
Autor:
James T. Earnest, Julie M. Fox, Jon H. Ritter, Rita E. Chen, Natasha M. Kafai, Richard D. Head, Annette Robichaud, Broc T. McCune, Adam L. Bailey, Sarah Dort, Michael J. Holtzman, Shamus P. Keeler, Emma S. Winkler, Liang I. Kang, Michael S. Diamond, Jinsheng Yu, Sharmila Nair
Publikováno v:
Nature Immunology
Although animal models have been evaluated for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, none have fully recapitulated the lung disease phenotypes seen in humans who have been hospitalized. Here, we evaluate transgenic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7e955026766c5e9b59df413a25fe97
Autor:
Natasha M. Kafai, Richard D. Head, Jon H. Ritter, Michael J. Holtzman, Jinsheng Yu, Michael S. Diamond, Julie M. Fox, Sarah Dort, Shamus P. Keeler, Emma S. Winkler, Liang I. Kang, Adam L. Bailey, Broc T. McCune, Annette Robichaud, James T. Earnest, Sharmila Nair, Rita E. Chen
Publikováno v:
bioRxiv
Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2) emerged in late 2019 and has spread worldwide resulting in the Coronavirus Disease 2019 (COVID-19) pandemic. Although animal models have been evaluated for SARS-CoV-2 infection, none have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fa13eba483c631914704fca91ca4be
https://doi.org/10.1101/2020.07.09.196188
https://doi.org/10.1101/2020.07.09.196188