Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Sharmila Masli"'
Autor:
Sharmila Masli, Esen K. Akpek
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 1999-2009 (2022)
Abstract Differentiating patients with Sjögren's syndrome (SS)‐associated dry eye from non‐SS dry eye is critical for monitoring and appropriate management of possible sight‐ or life‐threatening extraglandular complications associated with S
Externí odkaz:
https://doaj.org/article/b6b071afcffa4459ad91b95faa26934e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Conjunctival epithelium forms a barrier between the ocular surface microbial flora and the ocular mucosa. In addition to secreting gel-forming mucins, goblet cells, located in the conjunctival epithelium, help maintain local immune homeostasis by sec
Externí odkaz:
https://doaj.org/article/052f0344241f4c53aa9acfd6f0d86a1f
Autor:
Laura Soriano-Romaní, Fayaz A. Mir, Niharika Singh, Ian Chin, Ali Hafezi-Moghadam, Sharmila Masli
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5705 (2022)
To address the conflicting role of thrombospondin (TSP)-1 reported in acute and chronic pathologies, this study investigated the role of TSP-1 in regulating leukocyte recruitment and regulation of VCAM-1 expression using mouse models of uveitis. The
Externí odkaz:
https://doaj.org/article/a81c28a8a72942f1b9147ce3891f3d59
Autor:
Sharmila Masli, Darlene A. Dartt
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9112 (2020)
Sjögren’s syndrome (SS) is a systemic rheumatic disease that predominantly affects salivary and lacrimal glands resulting in oral and ocular dryness, respectively, referred to as sicca symptoms. The clinical presentation of ocular dryness includes
Externí odkaz:
https://doaj.org/article/1aae2d4d6e734562baa1660c60bc3059
Autor:
Laura Soriano-Romaní, Laura Contreras-Ruiz, Antonio López-García, Yolanda Diebold, Sharmila Masli
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 9 (2018)
Chronic inflammation of the ocular surface poses a risk of vision impairment. The understanding of the molecular mechanisms that are involved in the inflammatory response is critical to identify novel molecular targets. Recently, thrombospondin-1 (TS
Externí odkaz:
https://doaj.org/article/170e9b58a5b54b2886c4880c6e54606d
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3117 (2018)
The risk of developing lymphoma in patients with Sjögren’s syndrome (SS) is 44 times higher than in the normal population with the most common lymphomas derived from marginal zone B (MZB) cells. Current understanding of the role of MZB cells in SS
Externí odkaz:
https://doaj.org/article/d61e2121af6245a3acb6c891921e0a65
Autor:
Yukako Tatematsu, Qalbi Khan, Tomas Blanco, Jeffrey A. Bair, Robin R. Hodges, Sharmila Masli, Darlene A. Dartt
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3191 (2018)
Thrombospondin-1-deficient (TSP-1−/−) mice are used as an animal model of Sjögren’s Syndrome because they exhibit many of the symptoms associated with the autoimmune type of dry eye found in primary Sjögren’s Syndrome. This type of dry eye
Externí odkaz:
https://doaj.org/article/0e1842f5894a4dbcb844b2c3e59c811b
Autor:
Laura Contreras-Ruiz, Sharmila Masli
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120284 (2015)
Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins. Loss of these cells is associated with several chronic inflammatory disorders
Externí odkaz:
https://doaj.org/article/f4fdaf2dbbff44c483b34123c0379b8b
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75937 (2013)
Lacrimal gland inflammation during autoimmune Sjögren's syndrome (SS) leads to ocular surface inflammation - Keratoconjunctivitis sicca (KCS). This condition afflicts both the cornea and conjunctiva that form the ocular surface. Thrombospondin-1 (TS
Externí odkaz:
https://doaj.org/article/80192409ced94bb68262a4ac0b9965ca
Publikováno v:
Cornea. 39:991-997
Purpose Systemic implications necessitate the identification of dry eye patients with Sjogren syndrome (SS). This study aims to explore the utility of tear MUC5AC and inflammatory cytokine levels in the differential diagnosis of SS-related dry eye. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488fc4221c6ee222b800b13bcfee5a50
https://doi.org/10.1097/ico.0000000000002299
https://doi.org/10.1097/ico.0000000000002299