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Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms
Autor:
Amandeep Kaur, Alexandra E. Rojek, Emily Symes, Mariam T. Nawas, Anand A. Patel, Jay L. Patel, Payal Sojitra, Barina Aqil, Madina Sukhanova, Megan E. McNerney, Leo P. Wu, Aibek Akmatbekov, Jeremy Segal, Melissa Y. Tjota, Sandeep Gurbuxani, Jason X. Cheng, Su-Yeon Yeon, Harini V. Ravisankar, Carrie Fitzpatrick, Angela Lager, Michael W. Drazer, Caner Saygin, Pankhuri Wanjari, Panagiotis Katsonis, Olivier Lichtarge, Jane E. Churpek, Sharmila B. Ghosh, Ami B. Patel, Madhu P. Menon, Daniel A. Arber, Peng Wang, Girish Venkataraman
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Current therapies for high-grade TP53-mutated myeloid neoplasms (≥10% blasts) do not offer a meaningful survival benefit except allogeneic stem cell transplantation in the minority who achieve a complete response to first line therapy (CR1
Externí odkaz:
https://doaj.org/article/c0e050742d8c498c9f4fc3640be68aa0