Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sharleen Day"'
Autor:
Indrajit Sahu, Sachitanand M. Mali, Prasad Sulkshane, Cong Xu, Andrey Rozenberg, Roni Morag, Manisha Priyadarsini Sahoo, Sumeet K. Singh, Zhanyu Ding, Yifan Wang, Sharleen Day, Yao Cong, Oded Kleifeld, Ashraf Brik, Michael H. Glickman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
The 20S particle is part of the 26S proteasome, but also exists as a free complex. Here, the authors outline signature activities of the 20S and combine chemical, structural, functional and proteomic assays to show that the 20S can degrade ubiquitin
Externí odkaz:
https://doaj.org/article/46cc92bf4c3f4fcfb5bb5b4fa465398a
Autor:
Cong Xu, Indrajit Sahu, Andrey Rozenberg, Roni Morag, Sumeet K. Singh, Yao Cong, Manisha Priyadarsini Sahoo, Sachitanand M. Mali, Michael H. Glickman, Zhanyu Ding, Sharleen Day, Prasad Sulkshane, Ashraf Brik, Oded Kleifeld, Yifan Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
The proteasome, the primary protease for ubiquitin-dependent proteolysis in eukaryotes, is usually found as a mixture of 30S, 26S, and 20S complexes. These complexes have common catalytic sites, which makes it challenging to determine their distincti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d4b8d1326c3cace48f1bd38a2e9fa4
Autor:
Mary E. Skinner, Adam B. Stein, David A. Sinclair, Anthony Andren, Maccani Mw, Angela H. Guo, David B. Lombard, Sharleen Day, Long Zhang, Costas A. Lyssiotis, Davis Nj, Michan S, Baliira Rk, Surinder Kumar
Heart failure (HF) is defined as an inability of the heart to pump blood adequately to meet the body’s metabolic demands. HF with reduced systolic function is characterized by cardiac hypertrophy, ventricular fibrosis and remodeling, and decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c312b2dcd2eba6b1efa0d2ea8e3ec38a
https://doi.org/10.1101/2021.06.15.448619
https://doi.org/10.1101/2021.06.15.448619
Autor:
Zhanyu Ding, Cong Xu, Indrajit Sahu, Sumeet K. Singh, Andrey Rozenberg, Manisha Priyadarsini Sahoo, Yifan Wang, Prasad Sulkshane, Sachitanand M. Mali, Roni Morag, Yao Cong, Michael H. Glickman, Sharleen Day, Ashraf Brik, Oded Kleifeld
Publikováno v:
BioRxIV
bioRxiv
bioRxiv
Careful removal of unwanted proteins is necessary for cell survival. The primary constitutive intracellular protease is the 26S proteasome complex, often found in equilibrium with its free catalytic subcomplex– the 20S core particle. Protein degrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c28de01de89fa73cc779b4f8d1e812a