Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shariqa Aisha"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer treatment strategies are evolving due to innate and acquired resistance capacity, governed by genetic, epigenetic, proteomic, metabolic, or microenvironmental
Externí odkaz:
https://doaj.org/article/9d7fbf06779c4a2da350eb7763adea4c
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 4, Iss , Pp 100037- (2022)
Background: Baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, member of the inhibitor of apoptosis (IAP), is a multitasking protein and among the top 100 deregulated genes in breast cancer patients. It negatively regulates apoptosis of
Externí odkaz:
https://doaj.org/article/75657d24563d40378ff33b6a2fc366a3
Publikováno v:
Medical oncology (Northwood, London, England). 40(1)
Cellular ROS production participates in various cellular functions but its accumulation decides the cell fate. Malignant cells have higher levels of ROS and active antioxidant machinery, a characteristic hallmark of cancer with an outcome of activati
Autor:
Hina Qayoom, Umar Mehraj, Shazia Sofi, Shariqa Aisha, Abdullah Almilaibary, Mustfa Alkhanani, Manzoor Ahmad Mir
Publikováno v:
Medical Oncology. 39
The CDKs are known to play a critical role in cell cycle regulation process. Among the different groups of CDKs, CDK4 overexpression/hyperactivation is found to be present in many cancers and a specific CDK4 inhibitor, palbociclib has been recently a
Autor:
Shazia Sofi, Umar Mehraj, Hina Qayoom, Shariqa Aisha, Abdullah Almilaibary, Mustfa Alkhanani, Manzoor Ahmad Mir
Publikováno v:
Medical Oncology. 39
Cell cycle dysregulation is a characteristic hallmark of malignancies, which results in uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 (CDK1) is a member of the family of cell cycle regulatory proteins involve
Autor:
Shazia Sofi, Umar Mehraj, Hina Qayoom, Shariqa Aisha, Syed Mohammad Basheeruddin Asdaq, Abdullah Almilaibary, Manzoor A. Mir
Publikováno v:
Medical oncology (Northwood, London, England). 39(6)
Presently, breast cancer (BC) is one of the most common malignancies diagnosed and the leading cause of tumor-related deaths among women worldwide. Cell cycle dysregulation is one of the hallmarks of cancer, resulting in uncontrolled cell proliferati