Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shariq Madha"'
Autor:
Elisa Manieri, Guodong Tie, Ermanno Malagola, Davide Seruggia, Shariq Madha, Adrianna Maglieri, Kun Huang, Yuko Fujiwara, Kevin Zhang, Stuart H. Orkin, Timothy C. Wang, Ruiyang He, Neil McCarthy, Ramesh A. Shivdasani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract PDGFRA-expressing mesenchyme supports intestinal stem cells. Stomach epithelia have related niche dependencies, but their enabling mesenchymal cell populations are unknown, in part because previous studies pooled the gastric antrum and corpu
Externí odkaz:
https://doaj.org/article/92ebc7cc83f44ff5aa700ded18055634
Autor:
Elisa Manieri, Guodong Tie, Davide Seruggia, Shariq Madha, Adrianna Maglieri, Kun Huang, Yuko Fujiwara, Kevin Zhang, Stuart H. Orkin, Ruiyang He, Neil McCarthy, Ramesh A. Shivdasani
SUMMARYPDGFRA-expressing mesenchyme provides a niche for intestinal stem cells. Corresponding compartments are unknown in the stomach, where corpus and antral glandular epithelia have similar niche dependencies but are structurally distinct from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8bb63223596a91568acc07d4162bda7
https://doi.org/10.1101/2023.02.11.527728
https://doi.org/10.1101/2023.02.11.527728
Autor:
Wei-Ting Kuo, Clara Abraham, Jerrold R. Turner, Gurminder Singh, Shariq Madha, Christine B. Gurniak, Li Zuo, Matthew A. Odenwald
Publikováno v:
Gastroenterology
Backgrounds & Aims Increased permeability is implicated in the pathogenesis of intestinal disease. In vitro and in vivo studies have linked down-regulation of the scaffolding protein ZO-1, encoded by the TJP1 gene, to increased tight junction permeab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b77176d0a61440b0d687818774421c8
https://doi.org/10.1053/j.gastro.2021.08.047
https://doi.org/10.1053/j.gastro.2021.08.047
Autor:
Giuseppe Tarantino, Cora A. Ricker, Annette Wang, Will Ge, Tyler J. Aprati, Amy Y. Huang, Shariq Madha, Jiajia Chen, Yingxiao Shi, Marc Glettig, Dennie T. Frederick, Samuel Freeman, Marta M. Holovatska, Michael P. Manos, Lisa Zimmer, Alexander Rösch, Anne Zaremba, Brendan Reardon, Jihye Park, Haitham A. Elmarakeby, Bastian Schilling, Anita Giobbie-Hurder, Natalie I. Vokes, Elizabeth I. Buchbinder, Keith T. Flaherty, Rizwan Haq, Catherine J. Wu, Genevieve M. Boland, F. Stephen Hodi, Eliezer M. Van Allen, Dirk Schadendorf, David Liu
While the introduction of immune checkpoint blockade (ICB) has dramatically improved clinical outcomes for patients with advanced melanoma, a significant proportion of patients develop resistance to therapy, and mechanisms of resistance are poorly el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12ad22537de16d7f90a4002341f3c264
https://doi.org/10.1101/2022.12.11.519808
https://doi.org/10.1101/2022.12.11.519808
Autor:
Giuseppe Tarantino, Cora A. Ricker, Annette Wang, Will Ge, Amy Y. Huang, Shariq Madha, Jiajia Chen, Yingxiao Shi, Dennie T. Frederick, Samuel Freeman, Marta M. Holovatska, Michael P. Manos, Lisa Zimmer, Alexander Rösch, Anne Zaremba, Brendan Reardon, Jihye Park, Haitham Elmarakeby, Bastian Schilling, Anita Giobbie-Hurder, Natalie Vokes, Elizabeth I. Buchbinder, Keith Flaherty, Rizwan Haq, Catherine Wu, Genevieve Boland, F. Stephen Hodi, Eliezer Van Allen, Dirk Schadendorf, David Liu
Publikováno v:
Cancer Research. 83:965-965
Background: Despite significant advances, only a subset of patients with advanced melanoma treated with immune checkpoint blockade (ICB) experience durable responses, and biomarkers to predict response are limited. Further, while combination ICB has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b6e01016d1ec9308e5043bf4e74a85f
https://doi.org/10.1158/1538-7445.am2023-965
https://doi.org/10.1158/1538-7445.am2023-965
Autor:
Neil McCarthy, Guodong Tie, Shariq Madha, Ruiyang He, Judith Kraiczy, Adrianna Maglieri, Ramesh A. Shivdasani
Publikováno v:
Developmental Cell. 58:550-564.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d595b14518f768fd9beaf2e30c865bd
https://doi.org/10.1016/j.devcel.2023.02.012
https://doi.org/10.1016/j.devcel.2023.02.012
Autor:
Judith Kraiczy, Neil McCarthy, Ermanno Malagola, Guodong Tie, Shariq Madha, Dario Boffelli, Daniel E. Wagner, Timothy C. Wang, Ramesh A. Shivdasani
Publikováno v:
Cell Stem Cell. 30:433-449.e8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f686035005056af2df2db37c5b806d95
https://doi.org/10.1016/j.stem.2023.03.004
https://doi.org/10.1016/j.stem.2023.03.004
Publikováno v:
Genesdevelopment. 36(11-12)
The progeny of intestinal stem cells (ISCs) dedifferentiate in response to ISC attrition. The precise cell sources, transitional states, and chromatin remodeling behind this activity remain unclear. In the skin, stem cell recovery after injury preser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc770b1164754e4d50e375667c264b4b
https://pubmed.ncbi.nlm.nih.gov/35738677
https://pubmed.ncbi.nlm.nih.gov/35738677
Autor:
Neil McCarthy, Guodong Tie, Shariq Madha, Judith Kraiczy, Adrianna Maglieri, Ramesh Shivdasani
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cb0555169ff8ae44e08006a6d8367ac
https://doi.org/10.2139/ssrn.4149949
https://doi.org/10.2139/ssrn.4149949
Autor:
Adrianna Maglieri, Judith Kraiczy, Shariq Madha, Neil McCarthy, Ramesh A. Shivdasani, Guodong Tie
Wnt and Rspondin (RSPO) signaling triggers proliferation, and bone morphogenetic protein inhibitors (BMPi) impede differentiation, of intestinal stem cells (ISCs). Here we report that the functional ISC niche is a complex, multi-layered mesenchymal s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8761ccac5ece0a6787278831b3087ded
https://doi.org/10.1101/2021.09.28.462142
https://doi.org/10.1101/2021.09.28.462142