Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sharina Reyes"'
Autor:
Marvin J Sklar, Santina Maiolatesi, Noelle Patterson, Martha Sedegah, Keith Limbach, Nimfa Teneza-Mora, Ilin Chuang, K Monique Hollis-Perry, Jo Glenna Banania, Ivelese Guzman, Harini Ganeshan, Sharina Reyes, Michael R Hollingdale, Mimi Wong, Ashley Lindstrom, Anatalio Reyes, Yolanda Alcorta, Lindsey Garver, Kelli Bankard, Arnel Belmonte, Maria Belmonte, Jun Huang, Kalpana Gowda, Sandra Inoue, Rachel Velasco, Elke Bergmann-Leitner, Jack Hutter, Tida Lee, Nehkonti Adams, Sidhartha Chaudhury, Devin Hunt, Cindy Tamminga, Eleanor Berrie, Duncan Bellamy, Mustapha Bittaye, Katie Ewer, Carter Diggs, Lorraine A Soisson, Alison Lawrie, Adrian Hill, Thomas L Richie, Eileen Villasante, Judith E Epstein, Christopher A Duplessis
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256980 (2021)
BackgroundA DNA-prime/human adenovirus serotype 5 (HuAd5) boost vaccine encoding Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP) and Pf apical membrane antigen-1 (PfAMA1), elicited protection in 4/15 (27%) of subjects against controlled h
Externí odkaz:
https://doaj.org/article/4dc547617946467c9611eaa99d4458b4
Autor:
Martha Sedegah, Michael R Hollingdale, Harini Ganeshan, Maria Belmonte, Jun Huang, Arnel Belmonte, Sandra Inoue, Rachel Velasco, Bradley Hickey, Nimfa Teneza-Mora, Joanne Lumsden, Sharina Reyes, Jo Glenna Banania, Anatalio Reyes, Ivelese Guzman, Thomas L Richie, Judith E Epstein, Eileen Villasante
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256396 (2021)
BackgroundImmunization with radiation-attenuated sporozoites (RAS) by mosquito bites provides >90% sterile protection against Plasmodium falciparum malaria in humans. We conducted a clinical trial based on data from previous RAS clinical trials that
Externí odkaz:
https://doaj.org/article/976cc23ed31b4e119cfee358be5ef4ee
Autor:
Bradley Hickey, Nimfa Teneza-Mora, Joanne Lumsden, Sharina Reyes, Martha Sedegah, Lindsey Garver, Michael R Hollingdale, Jo Glenna Banania, Harini Ganeshan, Megan Dowler, Anatalio Reyes, Cindy Tamminga, Alexandra Singer, Alicia Simmons, Maria Belmonte, Arnel Belmonte, Jun Huang, Sandra Inoue, Rachel Velasco, Steve Abot, Carlos S Vasquez, Ivelese Guzman, Mimi Wong, Patrick Twomey, Mariusz Wojnarski, James Moon, Yolanda Alcorta, Santina Maiolatesi, Michele Spring, Silas Davidson, Sidhartha Chaudhury, Eileen Villasante, Thomas L Richie, Judith E Epstein
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233840 (2020)
BackgroundImmunization with radiation-attenuated sporozoites (RAS) by mosquito bite provides >90% sterile protection against Plasmodium falciparum (Pf) malaria in humans. RAS invade hepatocytes but do not replicate. CD8+ T cells recognizing parasite-
Externí odkaz:
https://doaj.org/article/09a1bfbcaf43443593836d98e5b0ffa5
Autor:
Cindy Tamminga, Martha Sedegah, David Regis, Ilin Chuang, Judith E Epstein, Michele Spring, Jose Mendoza-Silveiras, Shannon McGrath, Santina Maiolatesi, Sharina Reyes, Victoria Steinbeiss, Charlotte Fedders, Kathryn Smith, Brent House, Harini Ganeshan, Jennylynn Lejano, Esteban Abot, Glenna J Banania, Renato Sayo, Fouzia Farooq, Maria Belmonte, Jittawadee Murphy, Jack Komisar, Jackie Williams, Meng Shi, Donald Brambilla, Nalini Manohar, Nancy O Richie, Chloe Wood, Keith Limbach, Noelle B Patterson, Joseph T Bruder, Denise L Doolan, C Richter King, Carter Diggs, Lorraine Soisson, Daniel Carucci, Gail Levine, Sheetij Dutta, Michael R Hollingdale, Christian F Ockenhouse, Thomas L Richie
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25868 (2011)
A protective malaria vaccine will likely need to elicit both cell-mediated and antibody responses. As adenovirus vaccine vectors induce both these responses in humans, a Phase 1/2a clinical trial was conducted to evaluate the efficacy of an adenoviru
Externí odkaz:
https://doaj.org/article/97a1ce60fb5e4006ae377a92a4081a31
Autor:
Sharina Reyes, Anatalio Reyes, Judith E. Epstein, Michael R. Hollingdale, Bradley Hickey, Sandra Inoue, Eileen Villasante, Nimfa Teneza-Mora, Jun Huang, Harini Ganeshan, Jo Glenna Banania, Arnel Belmonte, Ivelese Guzman, Maria Belmonte, Rachel Velasco, Thomas L. Richie, Martha Sedegah, Joanne M. Lumsden
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0256396 (2021)
PLoS ONE, Vol 16, Iss 8, p e0256396 (2021)
Background Immunization with radiation-attenuated sporozoites (RAS) by mosquito bites provides >90% sterile protection against Plasmodium falciparum malaria in humans. We conducted a clinical trial based on data from previous RAS clinical trials that
Autor:
Arnel Belmonte, Ivelese Guzman, D Bellamy, Cindy Tamminga, Michael R. Hollingdale, Eleanor Berrie, Jo Glenna Banania, Elke S. Bergmann-Leitner, Martha Sedegah, Judith E. Epstein, Maria Belmonte, Sharina Reyes, Eileen Villasante, Anatalio Reyes, Yolanda Alcorta, Tida Lee, Rachel Velasco, Devin Hunt, Katie J. Ewer, Thomas L. Richie, Keith Limbach, Kalpana Gowda, Alison M. Lawrie, Jack Hutter, Marvin J Sklar, Nehkonti Adams, Noelle B. Patterson, Lindsey S. Garver, Ashley Lindstrom, Nimfa Teneza-Mora, M Bittaye, Lorraine Soisson, Carter L. Diggs, Mimi Wong, Harini Ganeshan, Ilin Chuang, Sandra Inoue, Adrian V. S. Hill, Christopher A. Duplessis, Jun Huang, K. Monique Hollis-Perry, Santina Maiolatesi, Kelli Bankard, Sidhartha Chaudhury
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256980 (2021)
PLoS ONE
PLoS ONE
BackgroundA DNA-prime/human adenovirus serotype 5 (HuAd5) boost vaccine encodingPlasmodium falciparum(Pf) circumsporozoite protein (PfCSP) and Pf apical membrane antigen-1 (PfAMA1), elicited protection in 4/15 (27%) of subjects against controlled hum
Autor:
Jun Huang, Anita Manoj, Matthew B. Laurens, Peter F. Billingsley, Arnel Belmonte, Mimi Wong, Ivelese Guzman, Martha Sedegah, Warfighter Ii Study Team, B. Kim Lee Sim, Thomas L. Richie, Judith E. Epstein, Tooba Murshedkar, Sharina Reyes, Harini Ganeshan, Stephen L. Hoffman, Lindsey S Garver Baldwin, Anusha Gunasekera, Kirsten E. Lyke, Sumana Chakravarty, Eric R. James, W Preston Church, Alexandra Singer, Eileen Villasante, Amelia Ozemoya, Glenna Banania, Maria Belmonte, Anatalio Reyes, Andrea A. Berry
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 73(7)
Background A live-attenuated Plasmodium falciparum sporozoite (SPZ) vaccine (PfSPZ Vaccine) has shown up to 100% protection against controlled human malaria infection (CHMI) using homologous parasites (same P. falciparum strain as in the vaccine). Us
Autor:
Judith E. Epstein, James E. Moon, Martha Sedegah, Silas A. Davidson, Patrick S. Twomey, Santina Maiolatesi, Jo Glenna Banania, Harini Ganeshan, Maria Belmonte, Sandra Inoue, Michele D. Spring, Megan Dowler, Joanne M. Lumsden, Lindsey S. Garver, Nimfa Teneza-Mora, Michael R. Hollingdale, Cindy Tamminga, Thomas L. Richie, Bradley Hickey, Rachel Velasco, Mariusz Wojnarski, Steve Abot, Sidhartha Chaudhury, Mimi Wong, Yolanda Alcorta, Sharina Reyes, Eileen Villasante, Jun Huang, Carlos S. Vasquez, Alexandra Singer, Anatalio Reyes, Alicia Simmons, Arnel Belmonte, Ivelese Guzman
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233840 (2020)
PLoS ONE
PLoS ONE
BackgroundImmunization with radiation-attenuated sporozoites (RAS) by mosquito bite provides >90% sterile protection against Plasmodium falciparum (Pf) malaria in humans. RAS invade hepatocytes but do not replicate. CD8+ T cells recognizing parasite-
Autor:
Peter F. Billingsley, Mary Carrington, Judith E. Epstein, Donna Tosh, Martha Sedegah, Amy Tillman, Natasha Kc, Minglin Li, Shon Remich, B. Kim Lee Sim, Elizabeth Saverino, Jun Huang, Arnel Belmonte, Richard C. Ruck, Kevin Hauns, Tao Li, Abraham G. Eappen, Debbie Padilla, Alexandra Singer, Anita Manoj, Robin Nielsen, Adam Ruben, Maria Belmonte, Lindsey S. Garver, Kara A. Moser, Silas A. Davidson, Sumana Chakravarty, Eric R. James, Harini Ganeshan, Jessica Case, Eileen Villasante, Thomas L. Richie, Tooba Murshedkar, Sharina Reyes, Stephen L. Hoffman, Joana C. Silva, April Stafford, James E. Moon, Patrick S. Twomey, Yonas Abebe, Esteban Abot, Susan Cicatelli, Jason A. Regules, Carlos S. Vasquez, Bradley Hickey, Kristopher M. Paolino, Anusha Gunasekera
Publikováno v:
JCI Insight. 2
BACKGROUND: A radiation-attenuated Plasmodium falciparum (Pf) sporozoite (SPZ) malaria vaccine, PfSPZ Vaccine, protected 6 of 6 subjects (100%) against homologous Pf (same strain as in the vaccine) controlled human malaria infection (CHMI) 3 weeks af
Autor:
Anita Kumar, Lolita Bebris, Susan F. Leitman, Bradley Hickey, Thomas C. Luke, Lucy M. L. Goh, Thomas B. Nutman, Mara P. Berzins, Joanne M. Lumsden, Ruobing Wang, Stephen L. Hoffman, Martha Sedegah, Daniel Freilich, Patricia de la Vega, Sharina Reyes, Esteban Abot, Gary T. Brice, Thomas L. Richie, Judith E. Epstein, Yupin Charoenvit, Daniel J. Carucci, Joao C. Aguiar, Michael R. Hollingdale, Denise L. Doolan, Harini Ganeshan, John B. Sacci
Publikováno v:
Malaria Journal
Background In this phase 1 clinical trial, healthy adult, malaria-naïve subjects were immunized with radiation-attenuated Plasmodium falciparum sporozoites (PfRAS) by mosquito bite and then underwent controlled human malaria infection (CHMI). The Pf