Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Shari R, Atilano"'
Autor:
Rodrigo Donato Costa, Farid José Thomaz Neto, M. Tarek Moustafa, Shari R. Atilano, Marilyn Chwa, Javier Cáceres-del-Carpi, Mohamed Hamid Mohamed, M. Cristina Kenney, Baruch D. Kuppermann
Publikováno v:
International Journal of Retina and Vitreous, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Purpose The present study tests the hypothesis that mitochondrial genes have retrograde signaling capacity that influences the expression of nuclear genes related to angiogenesis pathways. Cytoplasmic hybrid (cybrid) in vitro cell lines with
Externí odkaz:
https://doaj.org/article/45036aa2efb947bea20f5bdab0f2bd3c
Autor:
Kevin Schneider, Marilyn Chwa, Shari R. Atilano, Sonali Nashine, Nitin Udar, David S. Boyer, S. Michal Jazwinski, Michael V. Miceli, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 10, Pp 675-689 (2022)
Abstract Activation of the Simulator of Interferon Genes (STING) system by mitochondrial (mt) DNA can upregulate type 1 interferon genes and enhance immune responses to combat bacterial and viral infections. In cancers, the tumor‐derived DNA activa
Externí odkaz:
https://doaj.org/article/09bf357e9bfd42d796eda35f47c0bc9b
Autor:
Shari R. Atilano, Sina Abedi, Narcisa V. Ianopol, Mithalesh K. Singh, J Lucas Norman, Deepika Malik, Payam Falatoonzadeh, Marilyn Chwa, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
Cells, Vol 11, Iss 17, p 2655 (2022)
Mitochondrial (mt) DNA can be classified into haplogroups, which represent populations with different geographic origins. Individuals of maternal African backgrounds (L haplogroup) are more prone to develop specific diseases compared those with mater
Externí odkaz:
https://doaj.org/article/6a9ff33f61e44626ae55f0c5cdf9fcde
Autor:
Nasim Salimiaghdam, Lata Singh, Mithalesh K. Singh, Marilyn Chwa, Shari R. Atilano, Zahra Mohtashami, Anthony B. Nesburn, Baruch D. Kuppermann, Stephanie Y. Lu, M. Cristina Kenney
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 675 (2022)
We assessed the potential negative effects of bacteriostatic and bactericidal antibiotics on the AMD cybrid cell lines (K, U and J haplogroups). AMD cybrid cells were created and cultured in 96-well plates and treated with tetracycline (TETRA) and ci
Externí odkaz:
https://doaj.org/article/a23239b1136c4a09a66c438dc36b7bd3
Autor:
Shari R Atilano, Nitin Udar, Timothy A Satalich, Viraat Udar, Marilyn Chwa, M Cristina Kenney
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0246114 (2021)
PurposeMitochondrial (mt) DNA damage is associated with age-related macular degeneration (AMD) and other human aging diseases. This study was designed to quantify and characterize mtDNA low-frequency heteroplasmy single nucleotide polymorphisms (SNPs
Externí odkaz:
https://doaj.org/article/35dabe7f52a0467a930d0acb2e3c19c2
Autor:
Lata Singh, Nasim Salimiaghdam, Kevin Schneider, Angele Nalbandian, Marilyn Chwa, Shari R Atilano, Andrea Bao, M Cristina Kenney
Publikováno v:
BMJ Open Ophthalmology, Vol 5, Iss 1 (2020)
Background We aim to determine the possible adverse effects of ciprofloxacin (CPFX) and tetracycline (TETRA), as examples of bactericidal and bacteriostatic agents, respectively, on cultured human retinal pigment epithelial cells (ARPE-19).Methods Ce
Externí odkaz:
https://doaj.org/article/b225632cc6f7451290919d020cd4be45
Autor:
Sina Abedi, Gregory Yung, Shari R. Atilano, Kunal Thaker, Steven Chang, Marilyn Chwa, Kevin Schneider, Nitin Udar, Daniela Bota, M. Cristina Kenney
Publikováno v:
PeerJ, Vol 8, p e9908 (2020)
Background Drug therapy yields different results depending on its recipient population. Cisplatin, a commonly used chemotherapeutic agent, causes different levels of resistance and side effects for different patients, but the mechanism(s) are present
Externí odkaz:
https://doaj.org/article/ef7b066f4c99462ba14fb3f9dd0f107a
Autor:
Shari R Atilano, Daniel H Lee, Paula S Fukuhara, Marilyn Chwa, Anthony B Nesburn, Nitin Udar, Cristina Kenney
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 14, Iss 1, Pp 62-70 (2019)
Purpose: To compare the levels of gene expression for enzymes involved in production and elimination of reactive oxygen/nitrogen species (ROS/RNS) in normal human corneal cells (NL cells) with those in human corneal cells with keratoconus (KC cells)
Externí odkaz:
https://doaj.org/article/6ad195d8ae534db09f9ff1c9f6e66a31
Autor:
Zixuan Shao, Marilyn Chwa, Shari R. Atilano, John Park, Hampar Karageozian, Vicken Karageozian, M. Cristina Kenney
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 38:513-526
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fc7868a8872e004787212fcf4d13e3
https://doi.org/10.1089/jop.2022.0015
https://doi.org/10.1089/jop.2022.0015
Autor:
Tej H. Patel, Lucas Norman, Steven Chang, Sina Abedi, Catherine Liu, Marilyn Chwa, Shari R. Atilano, Kunal Thaker, Stephanie Lu, S. Michal Jazwinski, Michael V. Miceli, Nitin Udar, Daniela Bota, M. Cristina Kenney
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Cisplatin, a powerful antitumor agent, causes formation of DNA adducts, and activation of apoptotic pathways. Presently, cisplatin resistance develops in up to 70% of patients but the underlying molecular mechanism(s) are unclear and ther
Externí odkaz:
https://doaj.org/article/5ec2b421a256417c8358fc231cbeb719