Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shari Orlanski"'
Autor:
Efrat Katsman, Shari Orlanski, Filippo Martignano, Ilana Fox-Fisher, Ruth Shemer, Yuval Dor, Aviad Zick, Amir Eden, Iacopo Petrini, Silvestro G. Conticello, Benjamin P. Berman
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-25 (2022)
Abstract The Oxford Nanopore (ONT) platform provides portable and rapid genome sequencing, and its ability to natively profile DNA methylation without complex sample processing is attractive for point-of-care real-time sequencing. We recently demonst
Externí odkaz:
https://doaj.org/article/cc3c7d79da7946259dbc5e08c1d4faf7
Autor:
Melissa Popowski, Troy D. Templeton, Bum-Kyu Lee, Catherine Rhee, He Li, Cathrine Miner, Joseph D. Dekker, Shari Orlanski, Yehudit Bergman, Vishwanath R. Iyer, Carol F. Webb, Haley Tucker
Publikováno v:
Stem Cell Reports, Vol 2, Iss 1, Pp 26-35 (2014)
We show here that singular loss of the Bright/Arid3A transcription factor leads to reprograming of mouse embryonic fibroblasts (MEFs) and enhancement of standard four-factor (4F) reprogramming. Bright-deficient MEFs bypass senescence and, under stand
Externí odkaz:
https://doaj.org/article/4a81e6e80a0c47439d7ef2ef89fe7aa7
Autor:
Guy Ludwig, Deborah Nejman, Merav Hecht, Shari Orlanski, Monther Abu-Remaileh, Ofra Yanuka, Oded Sandler, Amichai Marx, Douglas Roberts, Nissim Benvenisty, Yehudit Bergman, Monica Mendelsohn, Howard Cedar
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96090 (2014)
Both mouse and human embryonic stem cells can be differentiated in vitro to produce a variety of somatic cell types. Using a new developmental tracing approach, we show that these cells are subject to massive aberrant CpG island de novo methylation t
Externí odkaz:
https://doaj.org/article/c8df0bbd1e724ee988f1669e3fd17f6b
Autor:
Efrat Katsman, Shari Orlanski, Filippo Martignano, Ilana Fox-Fisher, Ruth Shemer, Yuval Dor, Aviad Zick, Amir Eden, Iacopo Petrini, Silvestro G. Conticello, Benjamin P. Berman
DNA methylation (5mC) is a promising biomarker for detecting circulating tumor DNA (ctDNA), providing information on a cell9s genomic regulation, developmental lineage, and molecular age. Sequencing assays for detecting ctDNA methylation involve pre-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55b5a835a8cf5f9412e965874976ddb
https://doi.org/10.1101/2021.10.18.464684
https://doi.org/10.1101/2021.10.18.464684
Autor:
Sarah Harrison, Shane G. Poplawski, Shari Orlanski, Melvin Wei, Brandi Atteberry, Benjamin P. Berman, Terry Kelly
Publikováno v:
Journal of Clinical Oncology. 40:e15014-e15014
e15014 Background: Nucleosomes are the repeating unit of chromatin that contain important signals for proper genomic function and transcriptional activity. Upon cell death, chromatin is fragmented, and nucleosomes are released into circulation and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe38411a6c0e9c057a51a3cbc081201f
https://doi.org/10.1200/jco.2022.40.16_suppl.e15014
https://doi.org/10.1200/jco.2022.40.16_suppl.e15014
Autor:
Yuval Tabach, Michal Gropp, Ofra Yanuka, Tamar Kahan, Merav Hecht, Amalia Tabib, Ilana Keshet, Shari Orlanski, Nissim Benvenisty, Howard Cedar
Publikováno v:
The International Journal of Developmental Biology. 61:285-292
Fragile X syndrome is the most frequent cause of inherited intellectual disability. The primary molecular defect in this disease is the expansion of a CGG repeat in the 5' region of the fragile X mental retardation1 (FMR1) gene, leading to de novo me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e46bad58e1063f86a3c4ddd3d4a36b9
https://doi.org/10.1387/ijdb.170022hc
https://doi.org/10.1387/ijdb.170022hc
Autor:
Carol F. Webb, Catherine Rhee, Bum Kyu Lee, Troy D. Templeton, Melissa Popowski, He Li, Haley O. Tucker, Shari Orlanski, Cathrine A. Miner, Vishwanath R. Iyer, Joseph D. Dekker, Yehudit Bergman
Publikováno v:
Stem Cell Reports, Vol 2, Iss 1, Pp 26-35 (2014)
Stem Cell Reports
Stem Cell Reports
Summary We show here that singular loss of the Bright/Arid3A transcription factor leads to reprograming of mouse embryonic fibroblasts (MEFs) and enhancement of standard four-factor (4F) reprogramming. Bright-deficient MEFs bypass senescence and, und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f54ce74a46ade29607ff8b46515a36c
https://doi.org/10.1016/j.stemcr.2013.12.002
https://doi.org/10.1016/j.stemcr.2013.12.002
Autor:
Klaus Rajewsky, Rena Levin-Klein, Yael Skversky, Yitzhak Reizel, Howard Cedar, Verena Labi, Adam Spiro, Yehudit Bergman, Sergei B. Koralov, Michal Lichtenstein, Shari Orlanski
Significance Even though DNA methylation is known to be correlated with gene repression, it has never been demonstrated that this modification must indeed be removed from a gene in order for it to become activated during cell differentiation in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86629866e0b6a1e0aaecfdb6522eed74
https://europepmc.org/articles/PMC4983829/
https://europepmc.org/articles/PMC4983829/
Publikováno v:
Current Pharmaceutical Design. 14:184-196
During embryogenesis there is an exquisite orchestration of cellular division, movement, differentiation, and death. Cell death is one of the most important aspects of organization of the developing embryo, as alteration in timing, level, or pattern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e538f4d4a1daf133edcf92798a2611
https://doi.org/10.2174/138161208783378789
https://doi.org/10.2174/138161208783378789