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Autor:
Timothy J. Panella, Debbie Graham, Shari L Kretzschmer, Matt Mayo, Stephen K. Williamson, Michael Bastasch
Publikováno v:
Investigational New Drugs. 20:339-342
More active agents are needed in the treatment of metastatic non-small cell lung cancer. Pyrazoloacridine (PZA) is a 9-methoxy acridine compound containing a reducible 5-nitro substituent. Although the mechanism of action of PZA is unknown, the acrid