Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shari, Meyers"'
Autor:
Dawn E. Quelle, Michael D. Henry, Steven R. Grossman, J. Nathan Davis, Shari Meyers, David K. Meyerholz, Joseph J. Cullen, Kokou D. Zamba, Songhai Chen, Xiaoyun Tang, Xuefeng Zhang, Seema Paliwal, J. Matthew Barnes, Viviane Palhares Muniz
Pancreatic ductal adenocarcinoma (PDAC) is an incurable, highly metastatic disease that is largely resistant to existing treatments. A better understanding of the genetic basis of PDAC metastasis should facilitate development of improved therapies. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af3e80f03f2ca5eb99738ef4a5c2e78
https://doi.org/10.1158/1541-7786.c.6542334
https://doi.org/10.1158/1541-7786.c.6542334
Autor:
Thomas Yong, J. Nathan Davis, James A. Cardelli, Shari Meyers, Katie Fennell, Adam H. Greer, Marcie Fowler, Floyd Galiano, Yara W. Moustafa, Shu-Wing Ng, Ross S. Berkowitz
Publikováno v:
Journal of Cellular Physiology. 228:2350-2364
Core binding factor (CBF) is a heterodimeric transcription factor containing one of three DNA-binding proteins of the Runt-related transcription factor family (RUNX1-3) and the non-DNA-binding protein, CBFβ. RUNX1 and CBFβ are the most common targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25aac11f1e59aeb411180876990a8e72
https://doi.org/10.1002/jcp.24406
https://doi.org/10.1002/jcp.24406
Publikováno v:
Journal of Cellular Biochemistry. 112:2340-2351
The Notch receptor pathway provides a paradigm for juxtacrine signaling pathways and controls stem cell function, developmental cell fate decisions, and cellular differentiation. The Notch pathway is constitutively activated in human cancers by chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96526bace3cbc938262ddc8456b512cb
https://doi.org/10.1002/jcb.23157
https://doi.org/10.1002/jcb.23157
Autor:
Scott W. Hiebert, Shiva Gautam, K. Scott Luce, Tiffany C. Ellis, Brenda J. Chyla, Jeffrey L. Franklin, Andre J. Ouelette, Laura L. McGhee, Joseph M. Amann, Robert H. Whitehead, Robert J. Coffey, Andres Martinez, M. Kay Washington, Mary Ann Thompson, Amy Moore, Shari Meyers, Dana King, Joyce E. Ohm
Publikováno v:
Molecular and Cellular Biology. 25:9576-9585
Two members of the MTG/ETO family of transcriptional corepressors, MTG8 and MTG16, are disrupted by chromosomal translocations in up to 15% of acute myeloid leukemia cases. The third family member, MTGR1, was identified as a factor that associates wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06624fb92d0694e87265630c94aae556
https://doi.org/10.1128/mcb.25.21.9576-9585.2005
https://doi.org/10.1128/mcb.25.21.9576-9585.2005
Autor:
Laura McGhee, Liza Elliott, Avedis Kazanjian, Josh Bryan, H. Leighton Grimes, Shari Meyers, J. Nathan Davis
Publikováno v:
Journal of Cellular Biochemistry. 89:1005-1018
Gfi-1 and Gfi-1B can repress transcription and play important roles in hematopoietic cell survival and differentiation. Although these proteins are known to bind DNA through a C-terminal zinc-finger domain and may require an N-terminal SNAG domain (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a191575d81ab06e1b4bda1aeabd94bf3
https://doi.org/10.1002/jcb.10548
https://doi.org/10.1002/jcb.10548
Publikováno v:
Gene. 303:1-10
Cloning and characterization of the 8;21 chromosomal breakpoint identified AML1 on chromosome 21 and ETO (MTG8) on chromosome 8, and the resultant chimeric gene product, AML-1/ETO. The ETO gene family now includes three human members encoding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba7b17d8557171bacdc03a4cf7b8d2d
https://doi.org/10.1016/s0378-1119(02)01172-1
https://doi.org/10.1016/s0378-1119(02)01172-1
Autor:
James R. Downing, Hironori Harada, Shari Meyers, Noel Lenny, John Nip, Bart Lutterbach, Scott W. Hiebert, David K. Strom, Joseph M. Amann
Publikováno v:
Molecular and Cellular Biology. 21:6470-6483
t(8;21) and t(16;21) create two fusion proteins, AML-1-ETO and AML-1-MTG16, respectively, which fuse the AML-1 DNA binding domain to putative transcriptional corepressors, ETO and MTG16. Here, we show that distinct domains of ETO contact the mSin3A a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48178774536cda3a111ce64a7cc2de1
https://doi.org/10.1128/mcb.21.19.6470-6483.2001
https://doi.org/10.1128/mcb.21.19.6470-6483.2001
Publikováno v:
Journal of Virology. 75:2174-2184
Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell tumors in mice. TBLV is highly related to mouse mammary tumor virus (MMTV) except that TBLV long terminal repeats (LTRs) have a deletion of negative regulatory elements and a triplicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947904c1b9c09a1b34b48a4e084d8b4a
https://doi.org/10.1128/jvi.75.5.2174-2184.2001
https://doi.org/10.1128/jvi.75.5.2174-2184.2001
Publikováno v:
Oncogene. 19:3584-3597
ETO (MTG8) was first described due to its involvement in the (8;21) translocation frequently observed in acute myeloid leukemias. In the t(8;21) the AML1 gene on chromosome 21 is fused to ETO on chromosome 8. The resultant hybrid protein is comprised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6201d368cc7b1b9aad87411d037cc819
https://doi.org/10.1038/sj.onc.1203689
https://doi.org/10.1038/sj.onc.1203689
Autor:
Shari Meyers, Scott W. Hiebert
Publikováno v:
Journal of Cellular Biochemistry. 79:93-98
The nuclear matrix plays an important role in the functional organization of the nucleus in part by locally concentrating regulatory factors involved in nucleic acid metabolism. A number of nuclear regulatory proteins initially identified due to thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a22a203f7997cc31c701b19aa0c15b11
https://doi.org/10.1002/1097-4644(2000)79:35+<93::aid-jcb1131>3.0.co
https://doi.org/10.1002/1097-4644(2000)79:35+<93::aid-jcb1131>3.0.co