Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shardul Bhilocha"'
Autor:
Daniel L. Worthley, Rocio Lopez, Gail West, Guntram A. Grassl, Genevieve Doyon, Shardul Bhilocha, Florian Rieder, Dina Dejanovic, Satya Kurada, Ren Mao, Sara El Ouali, Claudio Fiocchi, Shuai Zhao, Paul L. Fox, Anja Schirbel, Michael Cruise, Peng Yao, Tammy Sadler, Carol A. de la Motte
Publikováno v:
Mucosal immunology
Background: Intestinal fibrosis leading to strictures remains a significant clinical problem in inflammatory bowel diseases (IBD). The role of bacterial components in activating intestinal mesenchymal cells and driving fibrogenesis is largely unexplo
Autor:
Cody C. McMillan, Christopher P. Phenix, Brady G. Vigliarolo, Morshed A. Chowdhury, Shardul Bhilocha, Ingeborg Zehbe, Ignace Adolfo Moya
Publikováno v:
Journal of Medicinal Chemistry. 57:6092-6104
Cathepsin B (CTB) is a cysteine protease believed to be an important therapeutic target or biomarker for several diseases including aggressive cancer, arthritis, and parasitic infections. The development of probes capable of assessing CTB activity in
Autor:
Tammy Sadler, Shardul Bhilocha, Carol A. de la Motte, Banu Gopalan, Eleni Stylianou, Sean P. Kessler, Florian Rieder, Claudio Fiocchi, Gail West
Publikováno v:
The American Journal of Pathology. 179:2660-2673
In addition to mesenchymal cells, endothelial cells may contribute to fibrosis through the process of endothelial-to-mesenchymal transition (EndoMT). We investigated whether human intestinal microvascular endothelial cells (HIMEC) undergo EndoMT and
Autor:
Wenlan Wang, Han Yuan, Monika Pandya, Hans-Georg Wisniewski, Carol A. de la Motte, Ripal Amin, Mary K. Cowman, Shardul Bhilocha, Jaclyn LoBello, Anastasia Shytuhina, Mihir Tank
Publikováno v:
Analytical Biochemistry. 417:41-49
Agarose and polyacrylamide gel electrophoresis systems for the molecular mass-dependent separation of hyaluronan (HA) in the size range of approximately 5–500 kDa have been investigated. For agarose-based systems, the suitability of different agaro
Autor:
Michael Cruise, Ren Mao, Florian Rieder, Sean P. Kessler, Gail West, Shardul Bhilocha, Shuai Zhao, Dina Dejanovic, Claudio Fiocchi, Anja Schirbel, Satya Kurada, Carol A. de la Motte
Publikováno v:
Gastroenterology. 154:S-130
Autor:
Sparkle Russell-Puleri, Mary K. Cowman, Jaclyn LoBello, Jovan Mijovic, Cherry C. Chen, Wei Jing, Shardul Bhilocha, Han Yuan, Monika Pandya, Dianne Ramkishun, Eraldi Skendaj
Publikováno v:
Analytical biochemistry. 417(1)
The molecular mass of the polysaccharide hyaluronan (HA) is an important determinant of its biological activity and physicochemical properties. One method currently used for the analysis of the molecular mass distribution of an HA sample is gel elect
Inflammation-induced endothelial-to-mesenchymal transition: a novel mechanism of intestinal fibrosis
Autor:
Florian, Rieder, Sean P, Kessler, Gail A, West, Shardul, Bhilocha, Carol, de la Motte, Tammy M, Sadler, Banu, Gopalan, Eleni, Stylianou, Claudio, Fiocchi
Publikováno v:
The American journal of pathology. 179(5)
In addition to mesenchymal cells, endothelial cells may contribute to fibrosis through the process of endothelial-to-mesenchymal transition (EndoMT). We investigated whether human intestinal microvascular endothelial cells (HIMEC) undergo EndoMT and
Autor:
Zhufeng Ouyang, Tammy Sadler, Florian Rieder, Gail West, Eleni Stylianou, Peng Yao, Claudio Fiocchi, Shardul Bhilocha, Anja Schirbel, Carol A. de la Motte, Paul L. Fox
Publikováno v:
Inflammatory Bowel Diseases. 19:S17